SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 107
GLY A 109
TYR A 111
VAL A   6
 SO4  A 192 (-3.5A)
SO4  A 192 (-3.1A)
None
None
 0.89A 1dbbH-1t35A:
undetectable
1dbbL-1t35A:
undetectable		 1dbbH-1t35A:
22.32
1dbbL-1t35A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		4 / 8 PHE A 101
GLY A 131
LEU A 172
PHE A   7
 None
 0.87A 1gsfC-1t35A:
undetectable		 1gsfC-1t35A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		4 / 6 HIS A 164
ILE A 130
ALA A  98
VAL A 117
 None
 1.04A 1hk1A-1t35A:
undetectable		 1hk1A-1t35A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		3 / 3 THR A 110
LEU A 114
VAL A 117
 SO4  A 192 (-3.6A)
None
None
 0.32A 1mz9E-1t35A:
undetectable		 1mz9E-1t35A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		4 / 8 VAL A   6
GLY A  58
THR A  59
ALA A  60
 None
 0.82A 2a1hA-1t35A:
undetectable
2a1hB-1t35A:
undetectable		 2a1hA-1t35A:
19.60
2a1hB-1t35A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		3 / 3 SER A  41
GLY A  44
GLY A   9
 None
None
SO4  A 192 (-3.2A)
 0.57A 3bogA-1t35A:
undetectable
3bogC-1t35A:
undetectable		 3bogA-1t35A:
undetectable
3bogC-1t35A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		5 / 8 GLY A  47
ALA A  50
ASP A  51
GLY A  26
LEU A  25
 None
 1.37A 3em6A-1t35A:
undetectable		 3em6A-1t35A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		5 / 8 GLY A  47
ASP A  51
GLY A  26
LEU A  25
VAL A  37
 None
 1.40A 3em6A-1t35A:
undetectable		 3em6A-1t35A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		3 / 3 TYR A  38
ARG A  42
SER A  41
 None
 1.09A 4dr2I-1t35A:
undetectable
4dr2J-1t35A:
undetectable		 4dr2I-1t35A:
17.80
4dr2J-1t35A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		4 / 8 LEU A  78
GLU A  80
MET A  94
ALA A  98
 None
 0.83A 4rjdA-1t35A:
undetectable
4rjdB-1t35A:
undetectable		 4rjdA-1t35A:
15.26
4rjdB-1t35A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		5 / 11 ALA A  52
ALA A  50
GLY A  57
GLY A  58
ALA A  30
 None
 1.02A 5lf3K-1t35A:
undetectable
5lf3L-1t35A:
undetectable		 5lf3K-1t35A:
21.60
5lf3L-1t35A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1t35 HYPOTHETICAL PROTEIN
YVDD, PUTATIVE
LYSINE DECARBOXYLASE
(Bacillus
subtilis) 		5 / 11 ALA A  52
ALA A  50
GLY A  57
GLY A  58
ALA A  30
 None
 1.02A 5lf3Y-1t35A:
undetectable
5lf3Z-1t35A:
undetectable		 5lf3Y-1t35A:
21.60
5lf3Z-1t35A:
22.67