SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		4 / 8 ILE A 489
PHE A 490
VAL A 507
SER A 470
 None
 1.14A 1kb9A-1t3gA:
undetectable
1kb9C-1t3gA:
undetectable
1kb9D-1t3gA:
undetectable
1kb9E-1t3gA:
0.0		 1kb9A-1t3gA:
17.36
1kb9C-1t3gA:
19.05
1kb9D-1t3gA:
21.09
1kb9E-1t3gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		3 / 3 SER A 410
VAL A 507
LEU A 473
 None
 0.70A 1yajG-1t3gA:
undetectable		 1yajG-1t3gA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		5 / 11 VAL A 507
LEU A 534
LEU A 527
TYR A 481
MET A 477
 None
 1.25A 2a15A-1t3gA:
undetectable		 2a15A-1t3gA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		4 / 5 PHE A 429
ILE A 510
GLY A 541
CYH A 544
 None
 1.26A 3r0lD-1t3gA:
undetectable		 3r0lD-1t3gA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		5 / 12 ILE A 448
TRP A 552
PHE A 551
ALA A 430
LEU A 431
 None
 1.11A 4o1zB-1t3gA:
undetectable		 4o1zB-1t3gA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		4 / 8 ILE A 510
LEU A 431
ILE A 474
THR A 478
 None
 0.84A 5uihA-1t3gA:
2.1		 5uihA-1t3gA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1t3g X-LINKED
INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1
(Homo
sapiens) 		4 / 6 LEU A 434
LYS A 440
GLU A 439
LEU A 446
 None
 1.36A 5xooA-1t3gA:
undetectable		 5xooA-1t3gA:
21.48