SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t3i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOM_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 11 ALA A 188
GLU A 190
LEU A 159
PHE A 162
LEU A 166
 None
 1.14A 1jomA-1t3iA:
undetectable		 1jomA-1t3iA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 GLU A 273
SER A  89
GLU A 245
GLU A 249
 None
 1.03A 1knyA-1t3iA:
0.0
1knyB-1t3iA:
0.0		 1knyA-1t3iA:
20.88
1knyB-1t3iA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 4 SER A  38
LEU A 298
TYR A 391
GLY A 229
 None
 1.31A 1liiA-1t3iA:
undetectable		 1liiA-1t3iA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 12 SER A 385
PHE A 345
LEU A 321
LEU A 390
LEU A  32
 2OS  A 602 ( 3.9A)
None
None
None
None
 1.40A 1p33C-1t3iA:
2.9		 1p33C-1t3iA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 HIS A 212
PRO A 211
SER A 179
THR A 373
 None
 1.22A 1p7lC-1t3iA:
undetectable		 1p7lC-1t3iA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 HIS A 212
PRO A 211
SER A 179
THR A 373
 None
 1.21A 1p7lD-1t3iA:
undetectable		 1p7lD-1t3iA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 HIS A 212
PRO A 211
SER A 179
THR A 373
 None
 1.21A 1rg9A-1t3iA:
undetectable		 1rg9A-1t3iA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 HIS A 212
PRO A 211
SER A 179
THR A 373
 None
 1.22A 1rg9C-1t3iA:
undetectable		 1rg9C-1t3iA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 HIS A 212
PRO A 211
SER A 179
THR A 373
 None
 1.21A 1rg9D-1t3iA:
undetectable		 1rg9D-1t3iA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 7 PHE A 240
LEU A 291
THR A  96
TYR A  95
 None
 1.16A 1rmtB-1t3iA:
3.5		 1rmtB-1t3iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 PHE A 240
LEU A 291
THR A  96
TYR A  95
 None
 1.10A 1rmtD-1t3iA:
3.5		 1rmtD-1t3iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 12 GLY A 143
ALA A 144
ASP A 119
GLY A 111
PRO A 134
 None
 0.99A 2b7zA-1t3iA:
undetectable		 2b7zA-1t3iA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 12 ILE A  85
ALA A 210
ALA A  99
LEU A 203
ILE A 103
 None
None
PLP  A 600 (-3.9A)
None
None
 1.04A 2h79A-1t3iA:
undetectable		 2h79A-1t3iA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 12 THR A 409
SER A 405
ASN A  25
ALA A 388
VAL A  30
 None
 1.29A 2nniA-1t3iA:
0.0		 2nniA-1t3iA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 9 ALA A 102
SER A 228
LEU A 291
VAL A  77
ILE A 238
 None
PLP  A 600 (-2.5A)
None
None
None
 1.34A 3claA-1t3iA:
0.0		 3claA-1t3iA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 12 ILE A  85
ALA A 210
ALA A  99
LEU A 203
ILE A 103
 None
None
PLP  A 600 (-3.9A)
None
None
 1.03A 3gwsX-1t3iA:
undetectable		 3gwsX-1t3iA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 6 VAL A  30
SER A 405
LEU A 329
ILE A 410
LEU A  32
 None
 1.45A 3kk6A-1t3iA:
undetectable		 3kk6A-1t3iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 6 PHE A  17
ASN A 394
PHE A 392
ALA A  10
 None
 1.13A 3t3sB-1t3iA:
undetectable		 3t3sB-1t3iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 7 PHE A  17
ASN A 394
PHE A 392
ALA A  10
 None
 1.05A 3t3sC-1t3iA:
undetectable		 3t3sC-1t3iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 PHE A  17
ASN A 394
PHE A 392
ALA A  10
 None
 1.08A 3t3sE-1t3iA:
undetectable		 3t3sE-1t3iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 7 PHE A  17
ASN A 394
PHE A 392
ALA A  10
 None
 1.06A 4ejgA-1t3iA:
0.0		 4ejgA-1t3iA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 12 ILE A 366
TYR A 393
PHE A  17
LEU A 298
HIS A 212
 None
 1.26A 4j03A-1t3iA:
undetectable		 4j03A-1t3iA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 11 GLY A 292
ALA A  82
VAL A 295
MET A 232
ILE A 238
 None
 1.39A 4j4vA-1t3iA:
undetectable		 4j4vA-1t3iA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 11 GLY A 292
ALA A  82
VAL A 295
MET A 232
ILE A 238
 None
 1.48A 4j4vD-1t3iA:
0.0
4j4vE-1t3iA:
undetectable		 4j4vD-1t3iA:
20.41
4j4vE-1t3iA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 11 GLY A 292
ARG A  78
ALA A  82
VAL A 295
MET A 232
 None
 1.50A 4j4vD-1t3iA:
0.0
4j4vE-1t3iA:
undetectable		 4j4vD-1t3iA:
20.41
4j4vE-1t3iA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 8 ALA A 340
VAL A 185
GLY A 331
VAL A 176
ILE A 178
 None
None
None
PLP  A 600 (-4.9A)
None
 1.43A 4ll3A-1t3iA:
undetectable		 4ll3A-1t3iA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 GLY A 237
ARG A  97
GLY A 239
GLU A 101
 None
 1.27A 4z2eB-1t3iA:
undetectable
4z2eC-1t3iA:
undetectable		 4z2eB-1t3iA:
21.91
4z2eC-1t3iA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 ARG A  97
GLY A 239
GLU A 101
SER A  38
 None
 1.28A 4z3oA-1t3iA:
undetectable
4z3oB-1t3iA:
undetectable		 4z3oA-1t3iA:
20.32
4z3oB-1t3iA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 7 ILE A 191
PHE A 157
VAL A 173
ILE A 122
 None
 0.98A 4zzbC-1t3iA:
undetectable
4zzbD-1t3iA:
undetectable		 4zzbC-1t3iA:
22.65
4zzbD-1t3iA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 SER A  38
ARG A  97
GLY A 239
GLU A 101
 None
 0.97A 5cdqA-1t3iA:
0.8
5cdqB-1t3iA:
0.4
5cdqC-1t3iA:
0.1		 5cdqA-1t3iA:
22.37
5cdqB-1t3iA:
18.81
5cdqC-1t3iA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 SER A  38
ARG A  97
GLY A 239
GLU A 101
 None
 0.98A 5cdqR-1t3iA:
0.9
5cdqS-1t3iA:
0.6
5cdqT-1t3iA:
1.1		 5cdqR-1t3iA:
22.37
5cdqS-1t3iA:
18.81
5cdqT-1t3iA:
22.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		6 / 8 ALA A  36
HIS A 128
ASN A 180
LYS A 231
ARG A 367
ARG A 387
 GOL  A 603 (-3.5A)
PLP  A 600 ( 3.6A)
GOL  A 603 ( 3.8A)
PLP  A 600 (-1.2A)
GOL  A 603 (-4.4A)
GOL  A 603 (-2.8A)
 0.37A 5db5A-1t3iA:
58.8
5db5B-1t3iA:
59.3		 5db5A-1t3iA:
48.19
5db5B-1t3iA:
48.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 SER A 209
ALA A 210
HIS A 177
LEU A 225
 None
 1.30A 5dzkb-1t3iA:
undetectable
5dzkp-1t3iA:
undetectable		 5dzkb-1t3iA:
18.37
5dzkp-1t3iA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 SER A 209
ALA A 210
HIS A 177
LEU A 225
 None
 1.35A 5dzkc-1t3iA:
undetectable
5dzkq-1t3iA:
undetectable		 5dzkc-1t3iA:
18.37
5dzkq-1t3iA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 5 SER A 209
ALA A 210
HIS A 177
LEU A 225
 None
 1.35A 5dzkf-1t3iA:
undetectable
5dzkt-1t3iA:
undetectable		 5dzkf-1t3iA:
18.37
5dzkt-1t3iA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 6 SER A 209
ALA A 210
HIS A 177
LEU A 225
 None
 1.30A 5dzkg-1t3iA:
undetectable
5dzku-1t3iA:
undetectable		 5dzkg-1t3iA:
18.37
5dzku-1t3iA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 8 ALA A 388
LEU A 406
LEU A 403
LEU A 329
LEU A 327
 None
 1.32A 5jqbA-1t3iA:
undetectable
5jqbB-1t3iA:
0.0		 5jqbA-1t3iA:
22.65
5jqbB-1t3iA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		5 / 10 ALA A  73
GLU A  75
LYS A  47
ALA A 293
GLY A 292
 None
 1.20A 5lf3V-1t3iA:
undetectable
5lf3W-1t3iA:
undetectable		 5lf3V-1t3iA:
21.60
5lf3W-1t3iA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		3 / 3 HIS A 230
SER A  38
LYS A  40
 PLP  A 600 (-4.0A)
None
None
 1.06A 5os7A-1t3iA:
undetectable		 5os7A-1t3iA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		4 / 8 HIS A 212
PRO A 211
SER A 179
THR A 373
 None
 1.16A 5t8sB-1t3iA:
undetectable		 5t8sB-1t3iA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		3 / 3 LEU A 342
ASN A 346
LEU A 321
 None
 0.70A 6exiA-1t3iA:
2.1		 6exiA-1t3iA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		3 / 3 HIS A 230
SER A  38
LYS A  40
 PLP  A 600 (-4.0A)
None
None
 1.06A 6gmdB-1t3iA:
undetectable		 6gmdB-1t3iA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1t3i PROBABLE CYSTEINE
DESULFURASE
(Synechocystis
sp.) 		3 / 3 ASP A 152
LEU A 151
ARG A 328
 None
2OS  A 602 (-4.9A)
2OS  A 602 (-4.1A)
 0.89A 7dfrA-1t3iA:
undetectable		 7dfrA-1t3iA:
18.98