SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_A_ECLA1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	1t3k	DUAL-SPECIFICITY TYROSINE PHOSPHATASE (Arabidopsis thaliana)	4 / 7	ILE A 55 LEU A 58 ILE A 7 ALA A 25	None	0.57A	6b5vA-1t3kA: undetectable 6b5vC-1t3kA: undetectable	6b5vA-1t3kA: 18.79 6b5vC-1t3kA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_B_ECLB1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	1t3k	DUAL-SPECIFICITY TYROSINE PHOSPHATASE (Arabidopsis thaliana)	4 / 7	ALA A 25 ILE A 55 LEU A 58 ILE A 7	None	0.59A	6b5vA-1t3kA: undetectable 6b5vB-1t3kA: undetectable	6b5vA-1t3kA: 18.79 6b5vB-1t3kA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_C_ECLC1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	1t3k	DUAL-SPECIFICITY TYROSINE PHOSPHATASE (Arabidopsis thaliana)	4 / 7	ILE A 55 LEU A 58 ILE A 7 ALA A 25	None	0.57A	6b5vC-1t3kA: undetectable 6b5vD-1t3kA: undetectable	6b5vC-1t3kA: 18.79 6b5vD-1t3kA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_D_ECLD1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	1t3k	DUAL-SPECIFICITY TYROSINE PHOSPHATASE (Arabidopsis thaliana)	4 / 7	ALA A 25 ILE A 55 LEU A 58 ILE A 7	None	0.57A	6b5vB-1t3kA: undetectable 6b5vD-1t3kA: undetectable	6b5vB-1t3kA: 18.79 6b5vD-1t3kA: 18.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["6B5V_A_ECLA1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","1t3k","DUAL-SPECIFICITY TYROSINE PHOSPHATASE","Arabidopsis thaliana",4,"ILE A  55;LEU A  58;ILE A   7;ALA A  25","None","0.57A","6b5vA-1t3kA:undetectable;6b5vC-1t3kA:undetectable","6b5vA-1t3kA:18.79;6b5vC-1t3kA:18.79"],["6B5V_B_ECLB1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","1t3k","DUAL-SPECIFICITY TYROSINE PHOSPHATASE","Arabidopsis thaliana",4,"ALA A  25;ILE A  55;LEU A  58;ILE A   7","None","0.59A","6b5vA-1t3kA:undetectable;6b5vB-1t3kA:undetectable","6b5vA-1t3kA:18.79;6b5vB-1t3kA:18.79"],["6B5V_C_ECLC1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","1t3k","DUAL-SPECIFICITY TYROSINE PHOSPHATASE","Arabidopsis thaliana",4,"ILE A  55;LEU A  58;ILE A   7;ALA A  25","None","0.57A","6b5vC-1t3kA:undetectable;6b5vD-1t3kA:undetectable","6b5vC-1t3kA:18.79;6b5vD-1t3kA:18.79"],["6B5V_D_ECLD1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","1t3k","DUAL-SPECIFICITY TYROSINE PHOSPHATASE","Arabidopsis thaliana",4,"ALA A  25;ILE A  55;LEU A  58;ILE A   7","None","0.57A","6b5vB-1t3kA:undetectable;6b5vD-1t3kA:undetectable","6b5vB-1t3kA:18.79;6b5vD-1t3kA:18.79"]]