SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t4b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 10 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 0.93A 1d4yA-1t4bA:
undetectable		 1d4yA-1t4bA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ARG A 361
ARG A 360
ILE A  95
 None
 0.64A 1uobA-1t4bA:
undetectable		 1uobA-1t4bA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 6 ILE A 280
VAL A 153
VAL A 118
ILE A 108
 None
 0.79A 1uwhB-1t4bA:
undetectable		 1uwhB-1t4bA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 11 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 0.98A 2o4pA-1t4bA:
undetectable		 2o4pA-1t4bA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 SER A 275
TYR A 161
HIS A 274
 None
 0.69A 2r2vD-1t4bA:
undetectable		 2r2vD-1t4bA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 GLY A   5
LEU A 366
ILE A  30
LEU A  85
TYR A  82
 None
 1.29A 3g9eA-1t4bA:
undetectable		 3g9eA-1t4bA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 10 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 0.96A 3lzvA-1t4bA:
undetectable		 3lzvA-1t4bA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 10 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 1.01A 3oxwC-1t4bA:
undetectable		 3oxwC-1t4bA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 7 ILE A  69
TYR A  77
THR A  78
ILE A  81
 None
 0.99A 3p50B-1t4bA:
undetectable		 3p50B-1t4bA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 7 ILE A  69
TYR A  77
THR A  78
ILE A  81
 None
 0.98A 3p50C-1t4bA:
undetectable		 3p50C-1t4bA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 7 ILE A  69
TYR A  77
THR A  78
ILE A  81
 None
 0.97A 3p50D-1t4bA:
0.0		 3p50D-1t4bA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 7 ILE A  69
TYR A  77
THR A  78
ILE A  81
 None
 0.94A 3p50E-1t4bA:
undetectable		 3p50E-1t4bA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE A 288
LEU A 147
GLY A 146
VAL A 304
VAL A 329
 None
 1.01A 4c9lA-1t4bA:
undetectable		 4c9lA-1t4bA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE A 288
LEU A 147
GLY A 146
VAL A 304
VAL A 329
 None
 1.01A 4c9lB-1t4bA:
undetectable		 4c9lB-1t4bA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE A 288
LEU A 147
GLY A 146
VAL A 304
VAL A 329
 None
 1.00A 4c9oA-1t4bA:
undetectable		 4c9oA-1t4bA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 ILE A 288
LEU A 147
GLY A 146
VAL A 304
VAL A 329
 None
 0.99A 4c9oB-1t4bA:
undetectable		 4c9oB-1t4bA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ARG A  20
THR A 326
TRP A 301
 None
 0.86A 4d7hA-1t4bA:
undetectable		 4d7hA-1t4bA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 8 ILE A  95
TRP A 353
GLY A 133
ASN A 115
 None
 0.89A 4fgjA-1t4bA:
3.5
4fgjB-1t4bA:
3.5		 4fgjA-1t4bA:
22.50
4fgjB-1t4bA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 8 SER A 143
LEU A 152
ALA A 149
LEU A 147
 None
 0.94A 4ikjA-1t4bA:
undetectable
4ikjB-1t4bA:
undetectable		 4ikjA-1t4bA:
19.18
4ikjB-1t4bA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 8 LEU A 152
ALA A 149
LEU A 147
SER A 143
 None
 0.92A 4ikkA-1t4bA:
undetectable
4ikkB-1t4bA:
undetectable		 4ikkA-1t4bA:
19.18
4ikkB-1t4bA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 8 SER A 143
LEU A 152
ALA A 149
LEU A 147
 None
 0.88A 4iklA-1t4bA:
undetectable
4iklB-1t4bA:
undetectable		 4iklA-1t4bA:
19.18
4iklB-1t4bA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 5 LEU A 123
GLY A 122
ILE A 110
GLN A 365
 None
 1.12A 4ma8C-1t4bA:
undetectable		 4ma8C-1t4bA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 6 PHE A 130
MET A 362
ARG A  86
ARG A 128
 None
 1.23A 4mk4B-1t4bA:
2.7		 4mk4B-1t4bA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 MET A 140
LEU A 144
GLY A 146
LEU A 342
THR A 249
 None
 1.09A 4p6xA-1t4bA:
undetectable		 4p6xA-1t4bA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 9 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 1.02A 4q1wA-1t4bA:
undetectable		 4q1wA-1t4bA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ARG A  20
THR A 326
TRP A 301
 None
 0.90A 4ug5A-1t4bA:
undetectable		 4ug5A-1t4bA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ARG A  20
THR A 326
TRP A 301
 None
 0.84A 4uglA-1t4bA:
undetectable		 4uglA-1t4bA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ASN A 307
LEU A 295
PHE A 345
 None
 0.79A 5dsgA-1t4bA:
undetectable		 5dsgA-1t4bA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ARG A  20
THR A 326
TRP A 301
 None
 0.84A 5g6cA-1t4bA:
undetectable		 5g6cA-1t4bA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 GLY A 168
GLY A 167
GLN A 350
 None
 0.41A 5imsA-1t4bA:
4.3		 5imsA-1t4bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ASP A 154
ASN A 250
GLN A 246
 None
 0.65A 5k7uA-1t4bA:
undetectable		 5k7uA-1t4bA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 6 GLU A 357
ARG A  20
LEU A  17
ARG A 360
 None
 1.15A 5l6eA-1t4bA:
undetectable
5l6eB-1t4bA:
undetectable		 5l6eA-1t4bA:
21.62
5l6eB-1t4bA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 ALA A  98
GLN A  73
THR A  78
 None
 0.69A 5n0oA-1t4bA:
undetectable		 5n0oA-1t4bA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 4 GLN A  39
GLN A  42
PRO A  45
ALA A  43
 None
 0.98A 5odcA-1t4bA:
2.2
5odcG-1t4bA:
2.3		 5odcA-1t4bA:
19.42
5odcG-1t4bA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG704_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 5 PRO A  45
ALA A  43
GLN A  39
GLN A  42
 None
 0.97A 5odcA-1t4bA:
2.2
5odcG-1t4bA:
2.3		 5odcA-1t4bA:
19.42
5odcG-1t4bA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 VAL A 268
TYR A 161
GLN A 162
 None
 0.60A 5qgkA-1t4bA:
0.0		 5qgkA-1t4bA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 VAL A 268
TYR A 161
GLN A 162
 None
 0.58A 5qgrA-1t4bA:
0.0		 5qgrA-1t4bA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 VAL A 268
TYR A 161
GLN A 162
 None
 0.58A 5qgtA-1t4bA:
0.0		 5qgtA-1t4bA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		4 / 7 LEU A  66
ALA A  62
ILE A  81
LEU A  85
 None
 0.81A 5te8C-1t4bA:
undetectable		 5te8C-1t4bA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 GLU A 174
HIS A 171
ARG A 267
 None
 0.82A 5uunA-1t4bA:
undetectable		 5uunA-1t4bA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		3 / 3 MET A 142
ASP A 112
ARG A  20
 None
 1.12A 5z6kA-1t4bA:
undetectable		 5z6kA-1t4bA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 0.96A 6dgxA-1t4bA:
undetectable		 6dgxA-1t4bA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 0.99A 6dh6A-1t4bA:
undetectable		 6dh6A-1t4bA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 1t4b ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE
(Escherichia
coli) 		5 / 12 LEU A 351
ALA A  97
ASP A  96
GLY A   8
VAL A  16
 None
 0.96A 6dilA-1t4bA:
undetectable		 6dilA-1t4bA:
13.29