SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		3 / 3 TRP A  82
ARG A  76
THR A  59
 None
 0.95A 1df7A-1t61A:
undetectable		 1df7A-1t61A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		5 / 10 GLY A 162
LEU A  83
GLN A  13
THR A  49
GLY A  48
 None
 1.33A 1kvlA-1t61A:
undetectable		 1kvlA-1t61A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 7 GLN A  37
PHE A  62
ARG A  76
GLU A  40
 None
 1.15A 1t9wA-1t61A:
undetectable		 1t9wA-1t61A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 8 MET A 145
LEU A  47
GLY A  48
LEU A 165
 None
 0.85A 1ya4A-1t61A:
undetectable		 1ya4A-1t61A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 6 GLU A 175
TYR A  81
ASP A  78
PHE A  62
 None
None
CL  A 810 (-4.9A)
None
 1.49A 2a3bB-1t61A:
undetectable		 2a3bB-1t61A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 8 ARG A  10
PRO A  18
GLY A  30
SER A  32
 None
 1.09A 3tzfB-1t61A:
undetectable		 3tzfB-1t61A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 5 GLU A 152
GLY A 150
TYR A  79
GLU A 175
 None
 1.47A 3w9tA-1t61A:
undetectable		 3w9tA-1t61A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 5 GLU A 152
GLY A 150
TYR A  79
GLU A 175
 None
 1.47A 3w9tC-1t61A:
undetectable		 3w9tC-1t61A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 5 GLU A 152
GLY A 150
TYR A  79
GLU A 175
 None
 1.47A 3w9tD-1t61A:
undetectable		 3w9tD-1t61A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 5 GLU A 152
GLY A 150
TYR A  79
GLU A 175
 None
 1.47A 3w9tG-1t61A:
undetectable		 3w9tG-1t61A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_1
(TUBULIN BETA-2B
CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		5 / 9 VAL A  36
ASP A  78
TYR A  35
PHE A 173
LEU A  33
 None
CL  A 810 (-4.9A)
None
None
None
 1.45A 5j2tB-1t61A:
undetectable		 5j2tB-1t61A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 5 PRO A  22
GLY A  23
THR A  24
LYS A  25
 None
 1.10A 5x23A-1t61A:
undetectable		 5x23A-1t61A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 6 PRO A  22
GLY A  23
THR A  24
LYS A  25
 None
 1.00A 5x24A-1t61A:
undetectable		 5x24A-1t61A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 6 PRO A  22
GLY A  23
THR A  24
LYS A  25
 None
 1.12A 5xxiA-1t61A:
undetectable		 5xxiA-1t61A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 1t61 TYPE IV COLLAGEN
(Bos
taurus) 		4 / 7 SER A 154
HIS A 146
GLY A 153
LEU A  47
 None
 1.11A 6btxA-1t61A:
undetectable		 6btxA-1t61A:
19.09