SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIN_A_TFPA154_1 (CALMODULIN)	1t62	CONSERVED HYPOTHETICAL PROTEIN (Enterococcus faecalis)	4 / 7	GLU A1127 LEU A1128 MET A1139 LEU A1141	None	1.01A	1linA-1t62A: undetectable	1linA-1t62A: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAA_D_DMED999_1 (ACETYLCHOLINESTERASE)	1t62	CONSERVED HYPOTHETICAL PROTEIN (Enterococcus faecalis)	4 / 8	GLY A1029 GLU A1119 TRP A1026 HIS A1120	None	1.08A	1maaD-1t62A: undetectable	1maaD-1t62A: 14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PK4_A_ACAA100_1 (HUMAN PLASMINOGEN KRINGLE 4)	1t62	CONSERVED HYPOTHETICAL PROTEIN (Enterococcus faecalis)	4 / 7	ASP A1072 ASP A1024 TRP A1026 PHE A1028	None	1.32A	2pk4A-1t62A: undetectable	2pk4A-1t62A: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KIV_A_ACAA100_1 (APOLIPOPROTEIN)	1t62	CONSERVED HYPOTHETICAL PROTEIN (Enterococcus faecalis)	4 / 7	ASP A1072 ASP A1024 TRP A1026 PHE A1028	None	1.33A	3kivA-1t62A: 0.0	3kivA-1t62A: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JVL_A_ESTA702_1 (ESTROGEN SULFOTRANSFERASE)	1t62	CONSERVED HYPOTHETICAL PROTEIN (Enterococcus faecalis)	4 / 9	PHE A1124 HIS A1120 PHE A1102 ILE A1092	None	1.37A	4jvlA-1t62A: 0.0	4jvlA-1t62A: 20.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LIN_A_TFPA154_1","CALMODULIN","1t62","CONSERVED HYPOTHETICAL PROTEIN","Enterococcus faecalis",4,"GLU A1127;LEU A1128;MET A1139;LEU A1141","None","1.01A","1linA-1t62A:undetectable","1linA-1t62A:21.21"],["1MAA_D_DMED999_1","ACETYLCHOLINESTERASE","1t62","CONSERVED HYPOTHETICAL PROTEIN","Enterococcus faecalis",4,"GLY A1029;GLU A1119;TRP A1026;HIS A1120","None","1.08A","1maaD-1t62A:undetectable","1maaD-1t62A:14.13"],["2PK4_A_ACAA100_1","HUMAN PLASMINOGEN KRINGLE 4","1t62","CONSERVED HYPOTHETICAL PROTEIN","Enterococcus faecalis",4,"ASP A1072;ASP A1024;TRP A1026;PHE A1028","None","1.32A","2pk4A-1t62A:undetectable","2pk4A-1t62A:19.85"],["3KIV_A_ACAA100_1","APOLIPOPROTEIN","1t62","CONSERVED HYPOTHETICAL PROTEIN","Enterococcus faecalis",4,"ASP A1072;ASP A1024;TRP A1026;PHE A1028","None","1.33A","3kivA-1t62A:0.0","3kivA-1t62A:20.86"],["4JVL_A_ESTA702_1","ESTROGEN SULFOTRANSFERASE","1t62","CONSERVED HYPOTHETICAL PROTEIN","Enterococcus faecalis",4,"PHE A1124;HIS A1120;PHE A1102;ILE A1092","None","1.37A","4jvlA-1t62A:0.0","4jvlA-1t62A:20.14"]]