SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t6n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		4 / 5 GLU A  55
THR A 103
LEU A 107
LEU A 104
 None
 1.23A 1u18B-1t6nA:
undetectable		 1u18B-1t6nA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		4 / 8 GLY A  46
ILE A  80
PHE A  99
PHE A 227
 None
 0.99A 3ko0B-1t6nA:
undetectable
3ko0J-1t6nA:
0.0		 3ko0B-1t6nA:
18.18
3ko0J-1t6nA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		4 / 8 GLY A  46
ILE A  80
PHE A  99
PHE A 227
 None
 0.95A 3ko0K-1t6nA:
0.0
3ko0S-1t6nA:
0.0		 3ko0K-1t6nA:
18.18
3ko0S-1t6nA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		3 / 3 LEU A 187
MET A 217
ASP A 196
 None
 0.82A 4j7xB-1t6nA:
undetectable		 4j7xB-1t6nA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		5 / 12 MET A 140
VAL A 143
VAL A 100
LEU A 104
VAL A 170
 None
 1.33A 4m11C-1t6nA:
undetectable		 4m11C-1t6nA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		4 / 5 LEU A 231
CYH A  87
CYH A  75
ASP A 196
 None
 1.22A 5mafA-1t6nA:
undetectable		 5mafA-1t6nA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 1t6n PROBABLE
ATP-DEPENDENT RNA
HELICASE
(Homo
sapiens) 		4 / 6 PRO A 246
LEU A 195
PHE A 227
LEU A 231
 None
 1.18A 5tl8A-1t6nA:
undetectable		 5tl8A-1t6nA:
18.34