SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 8 PHE 1  69
VAL 1  54
VAL 1  93
VAL 1  65
 None
 0.81A 1iwiA-1t6t1:
undetectable		 1iwiA-1t6t1:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 8 PHE 1  69
VAL 1  54
VAL 1  93
VAL 1  65
 None
 0.79A 1t86A-1t6t1:
undetectable		 1t86A-1t6t1:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 8 MET 1  82
ARG 1  98
LEU 1  58
VAL 1  54
 None
 0.99A 2bdmA-1t6t1:
undetectable		 2bdmA-1t6t1:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 6 LEU 1   8
ILE 1 106
ILE 1  78
MET 1  82
 None
 0.90A 2xkwB-1t6t1:
undetectable		 2xkwB-1t6t1:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 8 PHE 1  69
VAL 1  54
VAL 1  93
VAL 1  65
 None
 0.80A 2zujA-1t6t1:
undetectable		 2zujA-1t6t1:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		3 / 3 ASP 1  53
ARG 1  50
ASP 1  45
 None
 0.80A 4fp9A-1t6t1:
undetectable		 4fp9A-1t6t1:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		3 / 3 ASP 1  53
ARG 1  50
ASP 1  45
 None
 0.76A 4fp9C-1t6t1:
undetectable		 4fp9C-1t6t1:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		3 / 3 ASP 1  53
ARG 1  50
ASP 1  45
 None
 0.76A 4fp9F-1t6t1:
undetectable		 4fp9F-1t6t1:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 8 PHE 1  69
VAL 1  54
VAL 1  93
VAL 1  65
 None
 0.82A 4l4bA-1t6t1:
undetectable		 4l4bA-1t6t1:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		3 / 3 ASP 1  56
LYS 1  49
LEU 1  46
 None
 1.05A 4ptjA-1t6t1:
3.7		 4ptjA-1t6t1:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		5 / 11 GLU 1 110
ALA 1  34
LEU 1  35
LEU 1  68
LEU 1  15
 None
 1.13A 4wg0I-1t6t1:
undetectable
4wg0J-1t6t1:
undetectable
4wg0K-1t6t1:
undetectable		 4wg0I-1t6t1:
10.17
4wg0J-1t6t1:
10.17
4wg0K-1t6t1:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 7 TYR 1  51
GLY 1  48
SER 1  47
LEU 1  46
 None
 1.21A 5bphB-1t6t1:
4.0		 5bphB-1t6t1:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1t6t PUTATIVE PROTEIN
(Aquifex
aeolicus) 		4 / 8 PHE 1  69
VAL 1  54
VAL 1  93
VAL 1  65
 None
 0.81A 6cp4A-1t6t1:
undetectable		 6cp4A-1t6t1:
14.49