SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 8 LEU A 141
PHE A 138
ASN A 136
LEU A 123
 None
 0.93A 1e7cA-1t71A:
undetectable		 1e7cA-1t71A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 5 HIS A 233
GLU A 235
ALA A 217
SER A 222
 None
 1.02A 1errA-1t71A:
undetectable
1errB-1t71A:
0.0		 1errA-1t71A:
21.52
1errB-1t71A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 8 THR A 182
VAL A 246
GLY A 245
ILE A  39
 None
 0.78A 2a1mB-1t71A:
undetectable		 2a1mB-1t71A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 12 ILE A 145
PHE A 172
ASN A 122
THR A 121
LEU A  93
 None
 1.10A 2rlcA-1t71A:
0.0		 2rlcA-1t71A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 12 LEU A 124
ASN A 122
LEU A  93
GLY A 107
THR A  73
 None
 1.05A 2yhdA-1t71A:
undetectable		 2yhdA-1t71A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 6 SER A  52
TYR A  56
LEU A  53
LEU A  59
 None
 1.03A 3f33A-1t71A:
undetectable		 3f33A-1t71A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 9 PHE A 138
ILE A 179
ALA A 159
THR A 182
VAL A 155
 None
 1.04A 3me6D-1t71A:
undetectable		 3me6D-1t71A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 5 THR A 178
ILE A 154
PHE A 248
LEU A 152
 None
 1.43A 3tf1A-1t71A:
undetectable		 3tf1A-1t71A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		3 / 3 THR A 134
THR A 135
PHE A 138
 None
 0.84A 5cxvA-1t71A:
undetectable		 5cxvA-1t71A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 12 HIS A 185
ASP A  12
ASN A  44
LEU A  51
HIS A 158
 FE  A 301 (-3.5A)
FE  A 301 (-3.2A)
FE  A 301 (-2.7A)
None
FE  A 302 (-3.5A)
 1.32A 5dv4A-1t71A:
5.0		 5dv4A-1t71A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 12 LEU A 130
HIS A 185
ASP A  12
ASN A  44
LEU A  51
 None
FE  A 301 (-3.5A)
FE  A 301 (-3.2A)
FE  A 301 (-2.7A)
None
 1.45A 5dv4A-1t71A:
5.0		 5dv4A-1t71A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 12 ARG A  19
VAL A  40
LEU A  89
VAL A  83
GLY A  50
 None
 1.29A 5i8fA-1t71A:
0.0		 5i8fA-1t71A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 8 LYS A 255
SER A 198
THR A 194
ILE A 179
 None
 1.07A 5jhdE-1t71A:
undetectable
5jhdG-1t71A:
undetectable		 5jhdE-1t71A:
23.39
5jhdG-1t71A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 7 ASN A  71
HIS A  72
GLY A 216
ASN A  44
 FE  A 302 (-2.8A)
None
None
FE  A 301 (-2.7A)
 0.62A 5x7pA-1t71A:
undetectable		 5x7pA-1t71A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 7 HIS A  72
ASP A  12
GLY A 216
ASN A  44
 None
FE  A 301 (-3.2A)
None
FE  A 301 (-2.7A)
 1.03A 5x7pA-1t71A:
undetectable		 5x7pA-1t71A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		5 / 12 LEU A  26
PHE A   7
LEU A 191
ILE A 263
LEU A 152
 None
 1.19A 5y2tA-1t71A:
undetectable		 5y2tA-1t71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 1t71 PHOSPHATASE
(Mycoplasma
pneumoniae) 		4 / 7 GLY A 205
HIS A  72
ASN A  44
GLY A 216
 None
None
FE  A 301 (-2.7A)
None
 0.96A 6n7fA-1t71A:
undetectable		 6n7fA-1t71A:
14.12