SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t92'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_C_SAMC301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1t92	GENERAL SECRETION PATHWAY PROTEIN G (Klebsiella pneumoniae)	5 / 12	LEU A 89 LEU A 43 GLY A 63 ALA A 66 ALA A 70	None	1.18A	2bm9C-1t92A: undetectable	2bm9C-1t92A: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9N_A_CAMA1419_0 (CYTOCHROME P450)	1t92	GENERAL SECRETION PATHWAY PROTEIN G (Klebsiella pneumoniae)	4 / 8	LEU A 67 LEU A 64 GLY A 63 VAL A 109	None	0.79A	4c9nA-1t92A: undetectable	4c9nA-1t92A: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNY_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	1t92	GENERAL SECRETION PATHWAY PROTEIN G (Klebsiella pneumoniae)	5 / 12	ASP A 125 LEU A 67 LEU A 43 SER A 122 LEU A 64	None	1.18A	5hnyB-1t92A: undetectable	5hnyB-1t92A: 12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_1 (TUBULIN BETA CHAIN)	1t92	GENERAL SECRETION PATHWAY PROTEIN G (Klebsiella pneumoniae)	5 / 12	ASP A 125 LEU A 67 SER A 122 LEU A 64 GLN A 62	None	1.22A	6ew0F-1t92A: undetectable	6ew0F-1t92A: 24.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BM9_C_SAMC301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1t92","GENERAL SECRETION PATHWAY PROTEIN G","Klebsiella pneumoniae",5,"LEU A  89;LEU A  43;GLY A  63;ALA A  66;ALA A  70","None","1.18A","2bm9C-1t92A:undetectable","2bm9C-1t92A:17.72"],["4C9N_A_CAMA1419_0","CYTOCHROME P450","1t92","GENERAL SECRETION PATHWAY PROTEIN G","Klebsiella pneumoniae",4,"LEU A  67;LEU A  64;GLY A  63;VAL A 109","None","0.79A","4c9nA-1t92A:undetectable","4c9nA-1t92A:13.60"],["5HNY_B_TA1B601_1","TUBULIN BETA-2B CHAIN","1t92","GENERAL SECRETION PATHWAY PROTEIN G","Klebsiella pneumoniae",5,"ASP A 125;LEU A  67;LEU A  43;SER A 122;LEU A  64","None","1.18A","5hnyB-1t92A:undetectable","5hnyB-1t92A:12.44"],["6EW0_F_TA1F502_1","TUBULIN BETA CHAIN","1t92","GENERAL SECRETION PATHWAY PROTEIN G","Klebsiella pneumoniae",5,"ASP A 125;LEU A  67;SER A 122;LEU A  64;GLN A  62","None","1.22A","6ew0F-1t92A:undetectable","6ew0F-1t92A:24.27"]]