SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		3 / 3 THR A 211
LEU A 215
LEU A 222
 None
 0.59A 1mz9C-1t98A:
undetectable		 1mz9C-1t98A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 12 ALA A 139
ILE A 236
VAL A 164
ALA A 165
PHE A 168
 None
 0.72A 1uduB-1t98A:
1.0		 1uduB-1t98A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 12 ALA A 140
ASP A 141
VAL A 132
VAL A 253
ILE A 236
 None
 1.01A 2f8gA-1t98A:
undetectable		 2f8gA-1t98A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 12 MET A 178
LEU A 208
LEU A 207
GLY A 213
LEU A 215
 None
 1.27A 2j7xA-1t98A:
undetectable		 2j7xA-1t98A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		3 / 3 LEU A 123
MET A 127
MET A 178
 None
 0.77A 2vavF-1t98A:
undetectable		 2vavF-1t98A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		6 / 12 LEU A  24
ALA A  77
ILE A  78
LEU A  87
LEU A  86
MET A  47
 None
 1.44A 3adxB-1t98A:
undetectable		 3adxB-1t98A:
27.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		4 / 8 PHE A 168
VAL A 253
LEU A 160
ALA A 165
 None
 0.93A 3ax7A-1t98A:
2.8		 3ax7A-1t98A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		4 / 7 PHE A 168
VAL A 253
LEU A 160
ALA A 165
 None
 0.98A 3uniA-1t98A:
0.0		 3uniA-1t98A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		4 / 5 ILE A 171
GLN A 128
ILE A 131
GLU A 135
 None
 1.21A 4a99D-1t98A:
undetectable		 4a99D-1t98A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 12 MET A 178
LEU A 208
LEU A 207
GLY A 213
LEU A 215
 None
 1.26A 4j26A-1t98A:
undetectable		 4j26A-1t98A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 9 ALA A 143
ALA A 139
LEU A 136
LEU A 246
VAL A 249
 None
 1.30A 4or0A-1t98A:
2.4		 4or0A-1t98A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 12 SER A 209
GLN A 183
GLY A 213
THR A 214
GLN A 181
 None
 1.42A 5oj0A-1t98A:
undetectable		 5oj0A-1t98A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		5 / 12 VAL A 156
ASP A 148
HIS A 151
ALA A 143
ARG A 138
 None
 1.33A 5syfB-1t98A:
undetectable		 5syfB-1t98A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		4 / 5 THR A 174
ARG A 124
GLN A 219
ASP A 227
 None
 1.49A 6ectA-1t98A:
undetectable		 6ectA-1t98A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		4 / 5 THR A 174
ARG A 124
GLN A 219
ASP A 227
 None
 1.29A 6ecxA-1t98A:
undetectable		 6ecxA-1t98A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1t98 CHROMOSOME PARTITION
PROTEIN MUKF
(Escherichia
coli) 		4 / 6 VAL A  82
ASN A  75
ILE A  78
GLU A  49
 None
 0.98A 6h7uA-1t98A:
2.3		 6h7uA-1t98A:
20.40