SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1t9f PROTEIN 1D10
(Caenorhabditis
elegans) 		4 / 8 ILE A  94
ASP A  92
ILE A  88
GLY A  85
 None
 0.77A 4ac9C-1t9fA:
undetectable		 4ac9C-1t9fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1t9f PROTEIN 1D10
(Caenorhabditis
elegans) 		4 / 8 ILE A  94
ASP A  92
ILE A  88
GLY A  85
 None
 0.73A 4acaC-1t9fA:
undetectable		 4acaC-1t9fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1t9f PROTEIN 1D10
(Caenorhabditis
elegans) 		4 / 8 ILE A  94
ASP A  92
ILE A  88
GLY A  85
 None
 0.76A 4acbC-1t9fA:
undetectable		 4acbC-1t9fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1t9f PROTEIN 1D10
(Caenorhabditis
elegans) 		4 / 6 GLY A 187
GLY A 188
ASN A  36
ILE A 185
 None
 0.97A 4fglD-1t9fA:
undetectable		 4fglD-1t9fA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1t9f PROTEIN 1D10
(Caenorhabditis
elegans) 		4 / 6 PHE A 124
SER A 107
HIS A 155
LEU A 105
 None
 1.36A 5dzka-1t9fA:
undetectable
5dzko-1t9fA:
undetectable		 5dzka-1t9fA:
19.66
5dzko-1t9fA:
1.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1t9f PROTEIN 1D10
(Caenorhabditis
elegans) 		4 / 8 SER A 163
ALA A  61
ASP A  39
SER A  41
 None
 1.12A 5l5fY-1t9fA:
undetectable
5l5fZ-1t9fA:
undetectable		 5l5fY-1t9fA:
20.78
5l5fZ-1t9fA:
22.76