SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		3 / 3 ASP A  69
LYS A  48
ARG A  51
 None
 1.11A 1ra8A-1t9iA:
undetectable		 1ra8A-1t9iA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		4 / 6 LEU A  91
LEU A  88
LEU A  78
LEU A  58
 None
 0.86A 2ab2A-1t9iA:
undetectable		 2ab2A-1t9iA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  91
LEU A  88
PHE A  87
LEU A  84
VAL A  45
 None
 1.11A 2pnjA-1t9iA:
undetectable		 2pnjA-1t9iA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		5 / 11 LEU A  78
GLN A  44
ILE A  62
PHE A  87
LEU A  13
 None
 1.18A 2q6hA-1t9iA:
undetectable		 2q6hA-1t9iA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		5 / 11 LEU A  78
GLN A  44
ILE A  62
PHE A  87
LEU A  13
 None
 1.18A 2qeiA-1t9iA:
undetectable		 2qeiA-1t9iA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		4 / 7 LEU A  13
LEU A  10
PHE A   9
LEU A  58
 None
 0.97A 2vq5B-1t9iA:
undetectable		 2vq5B-1t9iA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_1
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		4 / 7 SER A 118
LYS A  34
PHE A  35
HIS A  37
 None
 1.28A 5dlvB-1t9iA:
0.0		 5dlvB-1t9iA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLW_A_5D5A905_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A  84
PHE A   9
PHE A  43
VAL A  64
TYR A  76
 None
 1.26A 5dlwA-1t9iA:
0.0		 5dlwA-1t9iA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1t9i DNA ENDONUCLEASE
I-CREI
(Chlamydomonas
reinhardtii) 		4 / 4 GLN A  92
THR A  89
GLU A 110
LEU A  41
 None
 1.45A 5m66A-1t9iA:
undetectable		 5m66A-1t9iA:
16.95