SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1t9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HLW_B_CE3B302_2 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	1t9m	PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE (Pseudomonas aeruginosa)	3 / 3	CYH A 175 PRO A 172 ASP A 84	None SO4 A 352 (-3.8A) None	0.97A	3hlwB-1t9mA: undetectable	3hlwB-1t9mA: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OS7_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	1t9m	PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE (Pseudomonas aeruginosa)	3 / 3	HIS A 82 SER A 85 LYS A 87	None FMN A 250 (-3.5A) FMN A 250 (-2.7A)	1.32A	5os7A-1t9mA: 1.2	5os7A-1t9mA: 19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GMD_B_ACTB402_0 (CASEIN KINASE II SUBUNIT ALPHA)	1t9m	PROBABLE PYRIDOXAMINE 5'-PHOSPHATE OXIDASE (Pseudomonas aeruginosa)	3 / 3	HIS A 82 SER A 85 LYS A 87	None FMN A 250 (-3.5A) FMN A 250 (-2.7A)	1.32A	6gmdB-1t9mA: 1.4	6gmdB-1t9mA: 19.48