SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1taq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.13A 1dz4A-1taqA:
undetectable		 1dz4A-1taqA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.13A 1dz4B-1taqA:
undetectable		 1dz4B-1taqA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 ASP A 120
ASP A 251
ASP A 144
 None
 0.66A 1eizA-1taqA:
undetectable		 1eizA-1taqA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 ASP A 120
ASP A 251
ASP A 144
 None
 0.67A 1ej0A-1taqA:
undetectable		 1ej0A-1taqA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 LEU A  98
LEU A 273
LEU A  52
LEU A  55
 None
 0.91A 1errA-1taqA:
undetectable		 1errA-1taqA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 9 LEU A  30
VAL A  44
GLY A  46
ALA A  48
SER A  50
 None
 1.18A 1pxxB-1taqA:
undetectable		 1pxxB-1taqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 10 LEU A  30
VAL A  44
GLY A  46
ALA A  48
SER A  50
 None
 1.18A 1pxxD-1taqA:
undetectable		 1pxxD-1taqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 VAL A  44
ALA A  43
HIS A  28
 None
 0.73A 1q23C-1taqA:
undetectable		 1q23C-1taqA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 VAL A  44
ALA A  43
HIS A  28
 None
 0.68A 1q23L-1taqA:
undetectable		 1q23L-1taqA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 5 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.16A 1t88B-1taqA:
0.0		 1t88B-1taqA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 TYR A 696
ARG A 617
GLN A 613
 None
 1.00A 1tw4A-1taqA:
undetectable		 1tw4A-1taqA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 GLU A 401
GLU A 397
LEU A 351
 None
 0.75A 1v8bA-1taqA:
3.3		 1v8bA-1taqA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 GLU A 401
GLU A 397
LEU A 351
 None
 0.71A 1v8bB-1taqA:
3.3		 1v8bB-1taqA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LEU A 574
PHE A 564
ARG A 595
 None
 0.61A 1xdkB-1taqA:
undetectable		 1xdkB-1taqA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LEU A 574
PHE A 564
ARG A 595
 None
 0.61A 1xdkF-1taqA:
undetectable		 1xdkF-1taqA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 7 GLU A 713
TRP A 706
MET A 747
GLY A 714
 None
 1.28A 2hs1B-1taqA:
undetectable		 2hs1B-1taqA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 5 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.16A 2m56A-1taqA:
0.0		 2m56A-1taqA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 9 GLY A 198
THR A 203
ALA A 204
LEU A 208
THR A 186
 None
 1.24A 2npnA-1taqA:
undetectable		 2npnA-1taqA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LEU A 549
PRO A 548
LEU A 552
 None
 0.52A 2po5B-1taqA:
2.8		 2po5B-1taqA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LEU A 549
PRO A 548
LEU A 552
 None
 0.59A 2po7B-1taqA:
2.4		 2po7B-1taqA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LYS A 127
ARG A 152
VAL A 136
 None
 1.11A 2r2vC-1taqA:
0.5
2r2vD-1taqA:
0.3		 2r2vC-1taqA:
7.16
2r2vD-1taqA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LYS A 531
ARG A 476
VAL A 474
 None
 0.88A 2r2vC-1taqA:
0.5
2r2vD-1taqA:
0.3		 2r2vC-1taqA:
7.16
2r2vD-1taqA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.20A 2zawA-1taqA:
0.0		 2zawA-1taqA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 PRO A 548
LEU A 552
ARG A 563
 None
 0.77A 3aqiA-1taqA:
4.0		 3aqiA-1taqA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 PRO A 548
LEU A 552
ARG A 563
 None
 0.79A 3aqiB-1taqA:
undetectable		 3aqiB-1taqA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 ASP A 144
HIS A  20
HIS A  21
ASP A  67
 None
None
ZN  A 900 (-4.5A)
None
 1.04A 3c0zC-1taqA:
undetectable		 3c0zC-1taqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 ASP A 120
ASP A 251
ASP A 144
 None
 0.70A 3douA-1taqA:
undetectable		 3douA-1taqA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 7 LEU A 367
ARG A 435
PRO A 301
GLY A 304
 None
 1.02A 3hcrB-1taqA:
4.0		 3hcrB-1taqA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 GLY A 597
LEU A 459
LEU A 456
ILE A 546
 None
 0.76A 3nbqB-1taqA:
undetectable		 3nbqB-1taqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 GLY A 597
LEU A 459
LEU A 456
ILE A 546
 None
 0.74A 3nbqC-1taqA:
undetectable		 3nbqC-1taqA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LYS A 762
ARG A 726
ASP A 372
 None
 1.37A 3o7wA-1taqA:
undetectable		 3o7wA-1taqA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 GLU A 434
LEU A 379
LEU A 412
 None
 0.69A 3ohtA-1taqA:
3.8		 3ohtA-1taqA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 GLU A 434
LEU A 379
LEU A 412
 None
 0.70A 3ohtB-1taqA:
3.9		 3ohtB-1taqA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 THR A  35
SER A  36
ARG A  37
 None
 0.50A 3phnA-1taqA:
undetectable		 3phnA-1taqA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.14A 3wrhE-1taqA:
0.0		 3wrhE-1taqA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 7 SER A 242
ASP A 244
GLY A 187
THR A 186
 None
 0.96A 4ac9C-1taqA:
undetectable		 4ac9C-1taqA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.15A 4g3rB-1taqA:
0.0		 4g3rB-1taqA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 5 PHE A 564
LEU A 560
VAL A 449
VAL A 783
 None
 1.16A 4l49A-1taqA:
0.0		 4l49A-1taqA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 12 HIS A 639
VAL A 631
GLY A 624
ASP A 625
PHE A 700
 None
 1.30A 4mubA-1taqA:
undetectable		 4mubA-1taqA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 7 LEU A 581
MET A 779
MET A 765
LEU A 574
 None
 1.03A 4okwA-1taqA:
undetectable		 4okwA-1taqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 PRO A 579
PHE A 598
LEU A 781
LEU A 560
 None
 0.93A 4qopC-1taqA:
undetectable		 4qopC-1taqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 12 LEU A 622
MET A 751
GLY A 755
ALA A 757
LEU A 760
 None
 1.18A 4rrwA-1taqA:
undetectable		 4rrwA-1taqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 12 LEU A 622
MET A 751
GLY A 755
ALA A 757
LEU A 760
 None
 1.18A 4rrwB-1taqA:
1.3		 4rrwB-1taqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		6 / 12 LEU A  30
VAL A  44
GLY A  46
ALA A  48
SER A  50
LEU A  51
 None
 1.22A 4rrxA-1taqA:
undetectable		 4rrxA-1taqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		6 / 12 LEU A  30
VAL A  44
GLY A  46
ALA A  48
SER A  50
LEU A  51
 None
 1.22A 4rrxB-1taqA:
2.0		 4rrxB-1taqA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 12 LEU A 622
MET A 751
GLY A 755
ALA A 757
LEU A 760
 None
 1.18A 4rrzA-1taqA:
undetectable		 4rrzA-1taqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 12 LEU A 622
MET A 751
GLY A 755
ALA A 757
LEU A 760
 None
 1.18A 4rrzB-1taqA:
1.3		 4rrzB-1taqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA303_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 4 LEU A 294
VAL A 332
GLU A 296
ARG A 334
 None
 1.36A 4ww7A-1taqA:
0.0		 4ww7A-1taqA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 6 TYR A  45
GLY A 279
SER A 280
LEU A 281
 None
 1.24A 5bphA-1taqA:
undetectable		 5bphA-1taqA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 4 TYR A  45
GLY A 279
SER A 280
LEU A 281
 None
 1.26A 5bphC-1taqA:
undetectable		 5bphC-1taqA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 LEU A 470
GLU A 530
LEU A 533
LEU A 484
 None
 1.23A 5dxeA-1taqA:
undetectable		 5dxeA-1taqA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 ILE A  63
ALA A 118
VAL A 121
HIS A  20
 None
 0.74A 5ecnD-1taqA:
undetectable		 5ecnD-1taqA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		6 / 12 LEU A  30
VAL A  44
GLY A  46
ALA A  48
SER A  50
LEU A  51
 None
 1.36A 5ikqB-1taqA:
undetectable		 5ikqB-1taqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 12 ALA A  97
VAL A  44
GLY A  46
ALA A  48
SER A  50
 None
 0.99A 5jw1A-1taqA:
1.3		 5jw1A-1taqA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		5 / 8 VAL A 103
ILE A  99
ALA A  23
VAL A  17
VAL A  64
 None
 1.28A 5l94A-1taqA:
undetectable		 5l94A-1taqA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		3 / 3 LEU A 813
ALA A 814
LEU A 723
 None
 0.53A 5uunB-1taqA:
undetectable		 5uunB-1taqA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 LEU A 470
GLU A 530
LEU A 533
LEU A 484
 None
 1.22A 6cbzA-1taqA:
undetectable		 6cbzA-1taqA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1taq TAQ DNA POLYMERASE
(Thermus
aquaticus) 		4 / 8 LEU A 311
LEU A 321
LEU A 351
GLY A 350
 None
 0.93A 6ce2A-1taqA:
undetectable		 6ce2A-1taqA:
8.70