SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		4 / 6 VAL B 161
ASN B  69
ILE A  28
ASN A  27
 None
 0.84A 1e06A-1tbaB:
1.9		 1e06A-1tbaB:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		4 / 7 ALA B 113
ILE B 103
ILE A  28
ASP A  29
 None
 1.02A 1yc5A-1tbaB:
undetectable		 1yc5A-1tbaB:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		4 / 5 ALA B 113
ILE B 103
ILE A  28
ASP A  29
 None
 0.99A 2h4jA-1tbaB:
undetectable		 2h4jA-1tbaB:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		5 / 12 PHE B 207
LEU A  68
ASP A  19
GLY A  57
ILE A  56
 None
 1.28A 2ycjA-1tbaB:
undetectable		 2ycjA-1tbaB:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1tba TRANSCRIPTION
INITIATION FACTOR
TFIID
(Saccharomyces
cerevisiae) 		4 / 7 THR B 112
VAL B 122
THR B 124
VAL B  71
 None
 0.34A 3em0B-1tbaB:
undetectable		 3em0B-1tbaB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
(Drosophila
melanogaster) 		3 / 3 ASN A  55
MET A  67
PHE A  25
 None
 1.09A 3g4lD-1tbaA:
undetectable		 3g4lD-1tbaA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		4 / 8 GLY A  57
ILE B 194
PHE A  25
PHE A  48
 None
 0.93A 3ko0K-1tbaA:
undetectable
3ko0S-1tbaA:
undetectable		 3ko0K-1tbaA:
21.69
3ko0S-1tbaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1tba TRANSCRIPTION
INITIATION FACTOR
TFIID
(Saccharomyces
cerevisiae) 		4 / 8 ILE B 146
LEU B 114
LEU B  82
PHE B 148
 None
 1.01A 4r38B-1tbaB:
undetectable		 4r38B-1tbaB:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 1tba TRANSCRIPTION
INITIATION FACTOR
TFIID
(Saccharomyces
cerevisiae) 		3 / 3 ARG B 220
GLN B 219
GLU B 129
 None
 0.91A 4tvtA-1tbaB:
0.0		 4tvtA-1tbaB:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		3 / 3 ARG B 107
LYS B 110
ARG A  53
 None
 1.01A 6c06D-1tbaB:
undetectable		 6c06D-1tbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1tba TRANSCRIPTION
INITIATION FACTOR
IID 230K CHAIN
TRANSCRIPTION
INITIATION FACTOR
TFIID
(Drosophila
melanogaster;
Saccharomyces
cerevisiae) 		4 / 8 GLN B  68
THR B 215
VAL B 161
LEU A  52
 None
 0.87A 6czmD-1tbaB:
undetectable
6czmF-1tbaB:
undetectable		 6czmD-1tbaB:
20.11
6czmF-1tbaB:
20.11