SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OLT_A_SAMA501_0 (OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE)	1tbu	PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1 (Saccharomyces cerevisiae)	5 / 12	THR A 78 ASP A 75 GLY A 74 ILE A 71 PHE A 108	None	1.35A	1oltA-1tbuA: undetectable	1oltA-1tbuA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SJ0_X_DXCX75_0 (CYTOCHROME C7)	1tbu	PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1 (Saccharomyces cerevisiae)	4 / 7	ILE A 112 PHE A 108 LYS A 40 GLY A 42	None	1.18A	3sj0X-1tbuA: undetectable	3sj0X-1tbuA: 17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R38_B_RBFB201_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	1tbu	PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1 (Saccharomyces cerevisiae)	4 / 8	THR A 40 ILE A 14 VAL A 18 LEU A 17	None	1.01A	4r38B-1tbuA: undetectable	4r38B-1tbuA: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_A_SAMA401_0 (PAVINE N-METHYLTRANSFERASE)	1tbu	PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1 (Saccharomyces cerevisiae)	5 / 12	GLY A 90 ASN A 86 THR A 56 VAL A 116 ALA A 115	None	1.06A	5kocA-1tbuA: undetectable	5kocA-1tbuA: 18.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OLT_A_SAMA501_0","OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE","1tbu","PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1","Saccharomyces cerevisiae",5,"THR A  78;ASP A  75;GLY A  74;ILE A  71;PHE A 108","None","1.35A","1oltA-1tbuA:undetectable","1oltA-1tbuA:16.74"],["3SJ0_X_DXCX75_0","CYTOCHROME C7","1tbu","PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1","Saccharomyces cerevisiae",4,"ILE A 112;PHE A 108;LYS A  40;GLY A  42","None","1.18A","3sj0X-1tbuA:undetectable","3sj0X-1tbuA:17.17"],["4R38_B_RBFB201_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","1tbu","PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1","Saccharomyces cerevisiae",4,"THR A  40;ILE A  14;VAL A  18;LEU A  17","None","1.01A","4r38B-1tbuA:undetectable","4r38B-1tbuA:18.00"],["5KOC_A_SAMA401_0","PAVINE N-METHYLTRANSFERASE","1tbu","PEROXISOMAL ACYL-COENZYME A THIOESTER HYDROLASE 1","Saccharomyces cerevisiae",5,"GLY A  90;ASN A  86;THR A  56;VAL A 116;ALA A 115","None","1.06A","5kocA-1tbuA:undetectable","5kocA-1tbuA:18.42"]]