SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tcs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMK_A_H4BA1427_1 (PHENYLALANINE-4-HYDR OXYLASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	VAL A 232 LEU A 195 SER A 193 LEU A 241 GLU A 160	None None NDP A 280 (-2.8A) None NDP A 280 ( 2.7A)	1.36A	1mmkA-1tcsA: undetectable	1mmkA-1tcsA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MMT_A_H4BA1426_1 (PHENYLALANINE-4-HYDR OXYLASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	VAL A 232 LEU A 195 SER A 193 LEU A 241 GLU A 160	None None NDP A 280 (-2.8A) None NDP A 280 ( 2.7A)	1.38A	1mmtA-1tcsA: undetectable	1mmtA-1tcsA: 22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1MRG_A_ADNA300_1 (ALPHA-MOMORCHARIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	7 / 9	ILE A 71 PHE A 83 GLY A 109 TYR A 111 ILE A 155 GLU A 160 ARG A 163	NDP A 280 (-4.5A) NDP A 280 ( 4.8A) NDP A 280 (-3.9A) NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.30A	1mrgA-1tcsA: 40.5	1mrgA-1tcsA: 63.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1MRJ_A_ADNA300_1 (ALPHA-TRICHOSANTHIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	7 / 8	ILE A 71 GLY A 109 TYR A 111 ILE A 155 SER A 159 GLU A 160 ARG A 163	NDP A 280 (-4.5A) NDP A 280 (-3.9A) NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 (-3.3A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.11A	1mrjA-1tcsA: 43.9	1mrjA-1tcsA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SDU_B_MK1B902_1 (PROTEASE RETROPEPSIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	LEU A 215 ALA A 230 GLY A 207 VAL A 213 ILE A 225	None	1.02A	1sduA-1tcsA: undetectable	1sduA-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_1 (RETINOIC ACID RECEPTOR, BETA)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 139 LEU A 154 ILE A 155 PHE A 83 LEU A 105	None None NDP A 280 (-3.9A) NDP A 280 ( 4.8A) None	1.01A	1xdkF-1tcsA: undetectable	1xdkF-1tcsA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_3 (POL POLYPROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.92A	2avvE-1tcsA: undetectable	2avvE-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BU8_A_TF4A1379_1 (PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 8	LEU A 154 ILE A 50 ILE A 71 ILE A 64	None None NDP A 280 (-4.5A) None	0.79A	2bu8A-1tcsA: undetectable	2bu8A-1tcsA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F80_B_017B301_1 (POL POLYPROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.88A	2f80A-1tcsA: undetectable	2f80A-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F80_B_017B301_2 (POL POLYPROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.90A	2f80B-1tcsA: undetectable	2f80B-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8G_B_017B401_1 (POL POLYPROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.92A	2f8gA-1tcsA: undetectable	2f8gA-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HS2_A_017A201_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.96A	2hs2A-1tcsA: undetectable	2hs2A-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HS2_A_017A201_2 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.96A	2hs2B-1tcsA: undetectable	2hs2B-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M9Q_B_BEZB251_0 (SERINE PROTEASE INHIBITOR SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 9	ILE A 71 PHE A 17 VAL A 62 ALA A 48 LEU A 21	NDP A 280 (-4.5A) None None None None	1.15A	2m9qA-1tcsA: undetectable	2m9qA-1tcsA: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNI_A_MTKA501_2 (CYTOCHROME P450 2C8)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 8	ILE A 155 ILE A 167 ILE A 125 ASN A 110	NDP A 280 (-3.9A) None None None	0.71A	2nniA-1tcsA: undetectable	2nniA-1tcsA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYM_A_1UNA1001_1 (PROTEASE RETROPEPSIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.93A	2pymA-1tcsA: undetectable	2pymA-1tcsA: 16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYM_A_1UNA1001_2 (PROTEASE RETROPEPSIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.92A	2pymB-1tcsA: undetectable	2pymB-1tcsA: 16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYN_A_1UNA1001_1 (PROTEASE RETROPEPSIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.94A	2pynA-1tcsA: undetectable	2pynA-1tcsA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYN_A_1UNA1001_2 (PROTEASE RETROPEPSIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.94A	2pynB-1tcsA: undetectable	2pynB-1tcsA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q63_A_1UNA1001_3 (PROTEASE RETROPEPSIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.95A	2q63B-1tcsA: undetectable	2q63B-1tcsA: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CYW_A_017A201_2 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.89A	3cywB-1tcsA: undetectable	3cywB-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1X_A_ROCA201_2 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.94A	3d1xB-1tcsA: undetectable	3d1xB-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL1_A_DR7A100_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	1.00A	3el1A-1tcsA: undetectable	3el1A-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK6_B_HCZB800_1 (GLUTAMATE RECEPTOR 2)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 10	LEU A 127 ILE A 171 SER A 11 LYS A 173 GLY A 172	None	1.24A	3ik6B-1tcsA: undetectable 3ik6E-1tcsA: undetectable	3ik6B-1tcsA: 22.73 3ik6E-1tcsA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILU_E_HFZE800_1 (GLUTAMATE RECEPTOR 2)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	ILE A 171 SER A 11 LYS A 173 GLY A 172 LEU A 127	None	1.27A	3iluB-1tcsA: 0.0 3iluE-1tcsA: 0.0	3iluB-1tcsA: 22.73 3iluE-1tcsA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JVY_B_017B401_2 (GAG-POL POLYPROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.93A	3jvyB-1tcsA: undetectable	3jvyB-1tcsA: 17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_D_ROCD201_3 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.96A	3k4vD-1tcsA: undetectable	3k4vD-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LZS_A_017A200_1 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.94A	3lzsA-1tcsA: undetectable	3lzsA-1tcsA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_A_ROCA101_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	6 / 12	LEU A 215 GLY A 231 ALA A 230 ASP A 229 ILE A 34 ILE A 225	None	1.16A	3ndtA-1tcsA: undetectable	3ndtA-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_A_ROCA101_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	6 / 12	LEU A 215 GLY A 231 ALA A 230 ASP A 229 VAL A 213 ILE A 225	None	1.21A	3ndtA-1tcsA: undetectable	3ndtA-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_D_ROCD100_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.97A	3ndtC-1tcsA: undetectable	3ndtC-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_A_ROCA101_2 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.98A	3nduB-1tcsA: undetectable	3nduB-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_D_ROCD100_2 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.96A	3nduD-1tcsA: undetectable	3nduD-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU6_B_478B401_2 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 10	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	1.02A	3nu6B-1tcsA: undetectable	3nu6B-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXV_B_478B200_1 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 9	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.95A	3oxvA-1tcsA: undetectable	3oxvA-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_A_DR7A100_2 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	LEU A 215 ALA A 230 ASP A 229 VAL A 213 ILE A 225	None	1.16A	3oxxB-1tcsA: undetectable	3oxxB-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_C_DR7C100_1 (HIV-1 PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.92A	3oxxC-1tcsA: undetectable	3oxxC-1tcsA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWM_B_017B402_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.93A	3pwmA-1tcsA: undetectable	3pwmA-1tcsA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWR_A_ROCA401_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.94A	3pwrA-1tcsA: undetectable	3pwrA-1tcsA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWR_A_ROCA401_3 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.97A	3pwrB-1tcsA: undetectable	3pwrB-1tcsA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_B_ROCB801_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.95A	3tkgA-1tcsA: undetectable	3tkgA-1tcsA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_B_ROCB801_2 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.93A	3tkgB-1tcsA: undetectable	3tkgB-1tcsA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKW_B_017B401_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.91A	3tkwA-1tcsA: undetectable	3tkwA-1tcsA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	6 / 12	LEU A 215 GLY A 231 ALA A 230 ASP A 229 VAL A 213 ILE A 225	None	1.29A	3tl9A-1tcsA: undetectable	3tl9A-1tcsA: 17.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3U6T_A_KANA4699_1 (RIBOSOME INACTIVATING PROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	9 / 10	TYR A 70 ILE A 71 GLU A 85 SER A 108 ASN A 110 TYR A 111 ILE A 155 GLU A 160 ARG A 163	NDP A 280 ( 4.7A) NDP A 280 (-4.5A) None None None NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.60A	3u6tA-1tcsA: 40.5	3u6tA-1tcsA: 64.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQB_A_FK5A114_1 (UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 8	PHE A 209 VAL A 233 ILE A 237 TYR A 164	None	0.86A	3uqbA-1tcsA: undetectable	3uqbA-1tcsA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H1N_A_CGEA505_1 (CYTOCHROME P450 2B4)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	ILE A 50 ILE A 18 ILE A 64 LEU A 25 ALA A 161	None	0.97A	4h1nA-1tcsA: undetectable	4h1nA-1tcsA: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H1N_A_CGEA505_1 (CYTOCHROME P450 2B4)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	ILE A 50 ILE A 64 LEU A 25 ALA A 162 ALA A 161	None	0.74A	4h1nA-1tcsA: undetectable	4h1nA-1tcsA: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HLA_A_017A200_1 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.86A	4hlaA-1tcsA: undetectable	4hlaA-1tcsA: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HLA_A_017A200_2 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.83A	4hlaB-1tcsA: undetectable	4hlaB-1tcsA: 15.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4JTP_A_ASCA802_0 (RRNA N-GLYCOSIDASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 5	TYR A 70 ILE A 71 ASN A 110 TYR A 111 ILE A 155	NDP A 280 ( 4.7A) NDP A 280 (-4.5A) None NDP A 280 ( 3.7A) NDP A 280 (-3.9A)	0.31A	4jtpA-1tcsA: 40.4	4jtpA-1tcsA: 64.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_B_STRB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	6 / 12	LEU A 215 ASN A 236 ILE A 237 GLY A 231 ALA A 230 ALA A 202	None	1.45A	4nkxB-1tcsA: undetectable	4nkxB-1tcsA: 19.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4O0O_A_URFA303_1 (RRNA N-GLYCOSIDASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 5	TYR A 70 ASN A 110 TYR A 111 ILE A 155 ARG A 163	NDP A 280 ( 4.7A) None NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.6A)	0.35A	4o0oA-1tcsA: 40.4	4o0oA-1tcsA: 64.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QB9_E_PARE500_1 (ENHANCED INTRACELLULAR SURVIVAL PROTEIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	SER A 61 LEU A 52 THR A 53 SER A 3 ASP A 57	None	1.47A	4qb9E-1tcsA: undetectable	4qb9E-1tcsA: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	3 / 3	ASN A 84 PHE A 82 TYR A 74	None	0.89A	4u15A-1tcsA: undetectable	4u15A-1tcsA: 22.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YP2_B_NCAB302_0 (RIBOSOME-INACTIVATIN G PROTEIN MOMORDIN I)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	7 / 9	ILE A 71 PHE A 83 GLY A 109 TYR A 111 ILE A 155 GLU A 160 ARG A 163	NDP A 280 (-4.5A) NDP A 280 ( 4.8A) NDP A 280 (-3.9A) NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.23A	4yp2B-1tcsA: 40.4	4yp2B-1tcsA: 65.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4YP2_B_NCAB302_0 (RIBOSOME-INACTIVATIN G PROTEIN MOMORDIN I)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	7 / 9	TYR A 70 ILE A 71 PHE A 83 GLY A 109 ILE A 155 GLU A 160 ARG A 163	NDP A 280 ( 4.7A) NDP A 280 (-4.5A) NDP A 280 ( 4.8A) NDP A 280 (-3.9A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.61A	4yp2B-1tcsA: 40.4	4yp2B-1tcsA: 65.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C8T_B_SAMB605_0 (GUANINE-N7 METHYLTRANSFERASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 11	GLY A 77 ASP A 78 ALA A 99 PHE A 96 TYR A 74	None	1.32A	5c8tB-1tcsA: 0.0	5c8tB-1tcsA: 19.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CF9_B_NCAB302_0 (RIBOSOME-INACTIVATIN G PROTEIN MOMORDIN I)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	7 / 9	ILE A 71 PHE A 83 GLY A 109 TYR A 111 ILE A 155 GLU A 160 ARG A 163	NDP A 280 (-4.5A) NDP A 280 ( 4.8A) NDP A 280 (-3.9A) NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.19A	5cf9B-1tcsA: 40.6	5cf9B-1tcsA: 65.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CF9_B_NCAB302_0 (RIBOSOME-INACTIVATIN G PROTEIN MOMORDIN I)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	7 / 9	TYR A 70 ILE A 71 PHE A 83 GLY A 109 ILE A 155 GLU A 160 ARG A 163	NDP A 280 ( 4.7A) NDP A 280 (-4.5A) NDP A 280 ( 4.8A) NDP A 280 (-3.9A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.57A	5cf9B-1tcsA: 40.6	5cf9B-1tcsA: 65.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC0_A_RBFA303_2 (RIBOFLAVIN TRANSPORTER RIBU)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	3 / 3	LYS A 173 LEU A 132 ILE A 18	None	0.76A	5kc0A-1tcsA: undetectable	5kc0A-1tcsA: 24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC4_A_RBFA201_2 (RIBOFLAVIN TRANSPORTER RIBU)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	3 / 3	LYS A 173 LEU A 132 ILE A 18	None	0.70A	5kc4A-1tcsA: undetectable	5kc4A-1tcsA: 24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_D_ACTD803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 4	GLU A 123 PRO A 181 ILE A 185 LEU A 183	None	1.33A	5m45D-1tcsA: 0.0	5m45D-1tcsA: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M45_G_ACTG803_0 (ACETONE CARBOXYLASE ALPHA SUBUNIT)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 4	GLU A 123 PRO A 181 ILE A 185 LEU A 183	None	1.31A	5m45G-1tcsA: 0.0	5m45G-1tcsA: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 4	VAL A 233 LEU A 31 ASN A 227 ASP A 229	None	1.04A	5vcyA-1tcsA: undetectable	5vcyA-1tcsA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_A_PCFA1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 7	LEU A 52 LEU A 127 ILE A 50 LEU A 21 ILE A 167	None	1.39A	5vkqA-1tcsA: undetectable 5vkqB-1tcsA: undetectable	5vkqA-1tcsA: 8.96 5vkqB-1tcsA: 8.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5Z3J_A_NCAA302_0 (ABRIN A-CHAIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 6	TYR A 70 ILE A 155 GLU A 160 ARG A 163	NDP A 280 ( 4.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.67A	5z3jA-1tcsA: 34.4	5z3jA-1tcsA: 34.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5Z3J_A_NCAA302_0 (ABRIN A-CHAIN)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	4 / 6	TYR A 111 ILE A 155 GLU A 160 ARG A 163	NDP A 280 ( 3.7A) NDP A 280 (-3.9A) NDP A 280 ( 2.7A) NDP A 280 ( 2.6A)	0.18A	5z3jA-1tcsA: 34.4	5z3jA-1tcsA: 34.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Z_D_9CRD501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	ALA A 135 ALA A 150 ILE A 155 LEU A 132 ALA A 131	None None NDP A 280 (-3.9A) None None	1.11A	6a5zD-1tcsA: undetectable	6a5zD-1tcsA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC608_1 (ALPHA-AMYLASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	3 / 3	TYR A 70 ALA A 162 LEU A 239	NDP A 280 ( 4.7A) None None	0.68A	6ag0C-1tcsA: undetectable	6ag0C-1tcsA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DGX_A_017A101_0 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.96A	6dgxA-1tcsA: undetectable	6dgxA-1tcsA: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DH6_A_017A104_0 (PROTEASE)	1tcs	TRICHOSANTHIN (Trichosanthes kirilowii)	5 / 12	LEU A 215 GLY A 231 ALA A 230 VAL A 213 ILE A 225	None	0.99A	6dh6A-1tcsA: undetectable	6dh6A-1tcsA: 16.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MMK_A_H4BA1427_1","PHENYLALANINE-4-HYDROXYLASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"VAL A 232;LEU A 195;SER A 193;LEU A 241;GLU A 160","None;None;NDP A 280 (-2.8A);None;NDP A 280 ( 2.7A)","1.36A","1mmkA-1tcsA:undetectable","1mmkA-1tcsA:22.15"],["1MMT_A_H4BA1426_1","PHENYLALANINE-4-HYDROXYLASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"VAL A 232;LEU A 195;SER A 193;LEU A 241;GLU A 160","None;None;NDP A 280 (-2.8A);None;NDP A 280 ( 2.7A)","1.38A","1mmtA-1tcsA:undetectable","1mmtA-1tcsA:22.15"],["1MRG_A_ADNA300_1","ALPHA-MOMORCHARIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",7,"ILE A  71;PHE A  83;GLY A 109;TYR A 111;ILE A 155;GLU A 160;ARG A 163","NDP A 280 (-4.5A);NDP A 280 ( 4.8A);NDP A 280 (-3.9A);NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.30A","1mrgA-1tcsA:40.5","1mrgA-1tcsA:63.97"],["1MRJ_A_ADNA300_1","ALPHA-TRICHOSANTHIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",7,"ILE A  71;GLY A 109;TYR A 111;ILE A 155;SER A 159;GLU A 160;ARG A 163","NDP A 280 (-4.5A);NDP A 280 (-3.9A);NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 (-3.3A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.11A","1mrjA-1tcsA:43.9","1mrjA-1tcsA:100.00"],["1SDU_B_MK1B902_1","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;ALA A 230;GLY A 207;VAL A 213;ILE A 225","None","1.02A","1sduA-1tcsA:undetectable","1sduA-1tcsA:16.87"],["1XDK_F_9CRF1600_1","RETINOIC ACID RECEPTOR, BETA","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 139;LEU A 154;ILE A 155;PHE A  83;LEU A 105","None;None;NDP A 280 (-3.9A);NDP A 280 ( 4.8A);None","1.01A","1xdkF-1tcsA:undetectable","1xdkF-1tcsA:21.38"],["2AVV_E_MK1E902_3","POL POLYPROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.92A","2avvE-1tcsA:undetectable","2avvE-1tcsA:16.87"],["2BU8_A_TF4A1379_1","PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"LEU A 154;ILE A  50;ILE A  71;ILE A  64","None;None;NDP A 280 (-4.5A);None","0.79A","2bu8A-1tcsA:undetectable","2bu8A-1tcsA:19.05"],["2F80_B_017B301_1","POL POLYPROTEIN;POL POLYPROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.88A","2f80A-1tcsA:undetectable","2f80A-1tcsA:16.87"],["2F80_B_017B301_2","POL POLYPROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.90A","2f80B-1tcsA:undetectable","2f80B-1tcsA:16.87"],["2F8G_B_017B401_1","POL POLYPROTEIN;POL POLYPROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.92A","2f8gA-1tcsA:undetectable","2f8gA-1tcsA:16.87"],["2HS2_A_017A201_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.96A","2hs2A-1tcsA:undetectable","2hs2A-1tcsA:16.87"],["2HS2_A_017A201_2","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.96A","2hs2B-1tcsA:undetectable","2hs2B-1tcsA:16.87"],["2M9Q_B_BEZB251_0","SERINE PROTEASE INHIBITOR;SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"ILE A  71;PHE A  17;VAL A  62;ALA A  48;LEU A  21","NDP A 280 (-4.5A);None;None;None;None","1.15A","2m9qA-1tcsA:undetectable","2m9qA-1tcsA:19.56"],["2NNI_A_MTKA501_2","CYTOCHROME P450 2C8","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"ILE A 155;ILE A 167;ILE A 125;ASN A 110","NDP A 280 (-3.9A);None;None;None","0.71A","2nniA-1tcsA:undetectable","2nniA-1tcsA:18.52"],["2PYM_A_1UNA1001_1","PROTEASE RETROPEPSIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.93A","2pymA-1tcsA:undetectable","2pymA-1tcsA:16.05"],["2PYM_A_1UNA1001_2","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.92A","2pymB-1tcsA:undetectable","2pymB-1tcsA:16.05"],["2PYN_A_1UNA1001_1","PROTEASE RETROPEPSIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.94A","2pynA-1tcsA:undetectable","2pynA-1tcsA:15.98"],["2PYN_A_1UNA1001_2","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.94A","2pynB-1tcsA:undetectable","2pynB-1tcsA:15.98"],["2Q63_A_1UNA1001_3","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.95A","2q63B-1tcsA:undetectable","2q63B-1tcsA:15.64"],["3CYW_A_017A201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.89A","3cywB-1tcsA:undetectable","3cywB-1tcsA:16.87"],["3D1X_A_ROCA201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.94A","3d1xB-1tcsA:undetectable","3d1xB-1tcsA:16.87"],["3EL1_A_DR7A100_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","1.00A","3el1A-1tcsA:undetectable","3el1A-1tcsA:16.87"],["3IK6_B_HCZB800_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 127;ILE A 171;SER A  11;LYS A 173;GLY A 172","None","1.24A","3ik6B-1tcsA:undetectable;3ik6E-1tcsA:undetectable","3ik6B-1tcsA:22.73;3ik6E-1tcsA:22.73"],["3ILU_E_HFZE800_1","GLUTAMATE RECEPTOR 2;GLUTAMATE RECEPTOR 2","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"ILE A 171;SER A  11;LYS A 173;GLY A 172;LEU A 127","None","1.27A","3iluB-1tcsA:0.0;3iluE-1tcsA:0.0","3iluB-1tcsA:22.73;3iluE-1tcsA:22.73"],["3JVY_B_017B401_2","GAG-POL POLYPROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.93A","3jvyB-1tcsA:undetectable","3jvyB-1tcsA:17.28"],["3K4V_D_ROCD201_3","HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.96A","3k4vD-1tcsA:undetectable","3k4vD-1tcsA:16.87"],["3LZS_A_017A200_1","HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.94A","3lzsA-1tcsA:undetectable","3lzsA-1tcsA:15.98"],["3NDT_A_ROCA101_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",6,"LEU A 215;GLY A 231;ALA A 230;ASP A 229;ILE A  34;ILE A 225","None","1.16A","3ndtA-1tcsA:undetectable","3ndtA-1tcsA:16.87"],["3NDT_A_ROCA101_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",6,"LEU A 215;GLY A 231;ALA A 230;ASP A 229;VAL A 213;ILE A 225","None","1.21A","3ndtA-1tcsA:undetectable","3ndtA-1tcsA:16.87"],["3NDT_D_ROCD100_1","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.97A","3ndtC-1tcsA:undetectable","3ndtC-1tcsA:16.87"],["3NDU_A_ROCA101_2","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.98A","3nduB-1tcsA:undetectable","3nduB-1tcsA:16.87"],["3NDU_D_ROCD100_2","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.96A","3nduD-1tcsA:undetectable","3nduD-1tcsA:16.87"],["3NU6_B_478B401_2","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","1.02A","3nu6B-1tcsA:undetectable","3nu6B-1tcsA:16.87"],["3OXV_B_478B200_1","HIV-1 PROTEASE;HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.95A","3oxvA-1tcsA:undetectable","3oxvA-1tcsA:16.87"],["3OXX_A_DR7A100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;ALA A 230;ASP A 229;VAL A 213;ILE A 225","None","1.16A","3oxxB-1tcsA:undetectable","3oxxB-1tcsA:16.87"],["3OXX_C_DR7C100_1","HIV-1 PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.92A","3oxxC-1tcsA:undetectable","3oxxC-1tcsA:16.87"],["3PWM_B_017B402_1","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.93A","3pwmA-1tcsA:undetectable","3pwmA-1tcsA:18.11"],["3PWR_A_ROCA401_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.94A","3pwrA-1tcsA:undetectable","3pwrA-1tcsA:18.11"],["3PWR_A_ROCA401_3","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.97A","3pwrB-1tcsA:undetectable","3pwrB-1tcsA:18.11"],["3TKG_B_ROCB801_1","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.95A","3tkgA-1tcsA:undetectable","3tkgA-1tcsA:17.84"],["3TKG_B_ROCB801_2","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.93A","3tkgB-1tcsA:undetectable","3tkgB-1tcsA:17.84"],["3TKW_B_017B401_1","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.91A","3tkwA-1tcsA:undetectable","3tkwA-1tcsA:17.84"],["3TL9_A_ROCA401_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",6,"LEU A 215;GLY A 231;ALA A 230;ASP A 229;VAL A 213;ILE A 225","None","1.29A","3tl9A-1tcsA:undetectable","3tl9A-1tcsA:17.84"],["3U6T_A_KANA4699_1","RIBOSOME INACTIVATING PROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",9,"TYR A  70;ILE A  71;GLU A  85;SER A 108;ASN A 110;TYR A 111;ILE A 155;GLU A 160;ARG A 163","NDP A 280 ( 4.7A);NDP A 280 (-4.5A);None;None;None;NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.60A","3u6tA-1tcsA:40.5","3u6tA-1tcsA:64.23"],["3UQB_A_FK5A114_1","UBIQUITIN-LIKE PROTEIN SMT3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"PHE A 209;VAL A 233;ILE A 237;TYR A 164","None","0.86A","3uqbA-1tcsA:undetectable","3uqbA-1tcsA:19.14"],["4H1N_A_CGEA505_1","CYTOCHROME P450 2B4","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"ILE A  50;ILE A  18;ILE A  64;LEU A  25;ALA A 161","None","0.97A","4h1nA-1tcsA:undetectable","4h1nA-1tcsA:18.31"],["4H1N_A_CGEA505_1","CYTOCHROME P450 2B4","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"ILE A  50;ILE A  64;LEU A  25;ALA A 162;ALA A 161","None","0.74A","4h1nA-1tcsA:undetectable","4h1nA-1tcsA:18.31"],["4HLA_A_017A200_1","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.86A","4hlaA-1tcsA:undetectable","4hlaA-1tcsA:15.64"],["4HLA_A_017A200_2","PROTEASE;PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.83A","4hlaB-1tcsA:undetectable","4hlaB-1tcsA:15.64"],["4JTP_A_ASCA802_0","RRNA N-GLYCOSIDASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"TYR A  70;ILE A  71;ASN A 110;TYR A 111;ILE A 155","NDP A 280 ( 4.7A);NDP A 280 (-4.5A);None;NDP A 280 ( 3.7A);NDP A 280 (-3.9A)","0.31A","4jtpA-1tcsA:40.4","4jtpA-1tcsA:64.23"],["4NKX_B_STRB601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",6,"LEU A 215;ASN A 236;ILE A 237;GLY A 231;ALA A 230;ALA A 202","None","1.45A","4nkxB-1tcsA:undetectable","4nkxB-1tcsA:19.18"],["4O0O_A_URFA303_1","RRNA N-GLYCOSIDASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"TYR A  70;ASN A 110;TYR A 111;ILE A 155;ARG A 163","NDP A 280 ( 4.7A);None;NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.6A)","0.35A","4o0oA-1tcsA:40.4","4o0oA-1tcsA:64.23"],["4QB9_E_PARE500_1","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"SER A  61;LEU A  52;THR A  53;SER A   3;ASP A  57","None","1.47A","4qb9E-1tcsA:undetectable","4qb9E-1tcsA:20.54"],["4U15_A_0HKA2001_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",3,"ASN A  84;PHE A  82;TYR A  74","None","0.89A","4u15A-1tcsA:undetectable","4u15A-1tcsA:22.20"],["4YP2_B_NCAB302_0","RIBOSOME-INACTIVATING PROTEIN MOMORDIN I","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",7,"ILE A  71;PHE A  83;GLY A 109;TYR A 111;ILE A 155;GLU A 160;ARG A 163","NDP A 280 (-4.5A);NDP A 280 ( 4.8A);NDP A 280 (-3.9A);NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.23A","4yp2B-1tcsA:40.4","4yp2B-1tcsA:65.04"],["4YP2_B_NCAB302_0","RIBOSOME-INACTIVATING PROTEIN MOMORDIN I","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",7,"TYR A  70;ILE A  71;PHE A  83;GLY A 109;ILE A 155;GLU A 160;ARG A 163","NDP A 280 ( 4.7A);NDP A 280 (-4.5A);NDP A 280 ( 4.8A);NDP A 280 (-3.9A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.61A","4yp2B-1tcsA:40.4","4yp2B-1tcsA:65.04"],["5C8T_B_SAMB605_0","GUANINE-N7 METHYLTRANSFERASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"GLY A  77;ASP A  78;ALA A  99;PHE A  96;TYR A  74","None","1.32A","5c8tB-1tcsA:0.0","5c8tB-1tcsA:19.76"],["5CF9_B_NCAB302_0","RIBOSOME-INACTIVATING PROTEIN MOMORDIN I","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",7,"ILE A  71;PHE A  83;GLY A 109;TYR A 111;ILE A 155;GLU A 160;ARG A 163","NDP A 280 (-4.5A);NDP A 280 ( 4.8A);NDP A 280 (-3.9A);NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.19A","5cf9B-1tcsA:40.6","5cf9B-1tcsA:65.04"],["5CF9_B_NCAB302_0","RIBOSOME-INACTIVATING PROTEIN MOMORDIN I","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",7,"TYR A  70;ILE A  71;PHE A  83;GLY A 109;ILE A 155;GLU A 160;ARG A 163","NDP A 280 ( 4.7A);NDP A 280 (-4.5A);NDP A 280 ( 4.8A);NDP A 280 (-3.9A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.57A","5cf9B-1tcsA:40.6","5cf9B-1tcsA:65.04"],["5KC0_A_RBFA303_2","RIBOFLAVIN TRANSPORTER RIBU","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",3,"LYS A 173;LEU A 132;ILE A  18","None","0.76A","5kc0A-1tcsA:undetectable","5kc0A-1tcsA:24.80"],["5KC4_A_RBFA201_2","RIBOFLAVIN TRANSPORTER RIBU","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",3,"LYS A 173;LEU A 132;ILE A  18","None","0.70A","5kc4A-1tcsA:undetectable","5kc4A-1tcsA:24.80"],["5M45_D_ACTD803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"GLU A 123;PRO A 181;ILE A 185;LEU A 183","None","1.33A","5m45D-1tcsA:0.0","5m45D-1tcsA:15.48"],["5M45_G_ACTG803_0","ACETONE CARBOXYLASE ALPHA SUBUNIT","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"GLU A 123;PRO A 181;ILE A 185;LEU A 183","None","1.31A","5m45G-1tcsA:0.0","5m45G-1tcsA:15.48"],["5VCY_A_DB8A401_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"VAL A 233;LEU A  31;ASN A 227;ASP A 229","None","1.04A","5vcyA-1tcsA:undetectable","5vcyA-1tcsA:19.75"],["5VKQ_A_PCFA1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A  52;LEU A 127;ILE A  50;LEU A  21;ILE A 167","None","1.39A","5vkqA-1tcsA:undetectable;5vkqB-1tcsA:undetectable","5vkqA-1tcsA:8.96;5vkqB-1tcsA:8.96"],["5Z3J_A_NCAA302_0","ABRIN A-CHAIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"TYR A  70;ILE A 155;GLU A 160;ARG A 163","NDP A 280 ( 4.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.67A","5z3jA-1tcsA:34.4","5z3jA-1tcsA:34.19"],["5Z3J_A_NCAA302_0","ABRIN A-CHAIN","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",4,"TYR A 111;ILE A 155;GLU A 160;ARG A 163","NDP A 280 ( 3.7A);NDP A 280 (-3.9A);NDP A 280 ( 2.7A);NDP A 280 ( 2.6A)","0.18A","5z3jA-1tcsA:34.4","5z3jA-1tcsA:34.19"],["6A5Z_D_9CRD501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"ALA A 135;ALA A 150;ILE A 155;LEU A 132;ALA A 131","None;None;NDP A 280 (-3.9A);None;None","1.11A","6a5zD-1tcsA:undetectable","6a5zD-1tcsA:18.52"],["6AG0_C_ACRC608_1","ALPHA-AMYLASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",3,"TYR A  70;ALA A 162;LEU A 239","NDP A 280 ( 4.7A);None;None","0.68A","6ag0C-1tcsA:undetectable","6ag0C-1tcsA:15.98"],["6DGX_A_017A101_0","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.96A","6dgxA-1tcsA:undetectable","6dgxA-1tcsA:15.04"],["6DH6_A_017A104_0","PROTEASE","1tcs","TRICHOSANTHIN","Trichosanthes kirilowii",5,"LEU A 215;GLY A 231;ALA A 230;VAL A 213;ILE A 225","None","0.99A","6dh6A-1tcsA:undetectable","6dh6A-1tcsA:16.37"]]