SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1td0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSF_B_PZIB802_0 (GLUTAMATE RECEPTOR 2)	1td0	HEAD DECORATION PROTEIN (Escherichia virus Lambda)	3 / 3	SER A 109 ASP A 19 ASN A 18	None	1.01A	3lsfB-1td0A: undetectable 3lsfE-1td0A: undetectable	3lsfB-1td0A: 20.48 3lsfE-1td0A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSF_E_PZIE802_0 (GLUTAMATE RECEPTOR 2)	1td0	HEAD DECORATION PROTEIN (Escherichia virus Lambda)	3 / 3	ASP A 19 ASN A 18 SER A 109	None	1.00A	3lsfB-1td0A: undetectable 3lsfE-1td0A: undetectable	3lsfB-1td0A: 20.48 3lsfE-1td0A: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_D_ACTD201_0 (RETINOL-BINDING PROTEIN 2)	1td0	HEAD DECORATION PROTEIN (Escherichia virus Lambda)	3 / 3	ASP A 95 HIS A 97 LYS A 99	None	0.94A	4qzuD-1td0A: undetectable	4qzuD-1td0A: 15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZSF_A_6T0A910_0 (TOLL-LIKE RECEPTOR 7)	1td0	HEAD DECORATION PROTEIN (Escherichia virus Lambda)	4 / 7	THR A 82 ILE A 88 THR A 85 PHE A 103	None	0.99A	5zsfA-1td0A: 0.0 5zsfB-1td0A: 0.0	5zsfA-1td0A: 17.59 5zsfB-1td0A: 17.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LSF_B_PZIB802_0","GLUTAMATE RECEPTOR 2","1td0","HEAD DECORATION PROTEIN","Escherichia virus Lambda",3,"SER A 109;ASP A  19;ASN A  18","None","1.01A","3lsfB-1td0A:undetectable;3lsfE-1td0A:undetectable","3lsfB-1td0A:20.48;3lsfE-1td0A:20.48"],["3LSF_E_PZIE802_0","GLUTAMATE RECEPTOR 2","1td0","HEAD DECORATION PROTEIN","Escherichia virus Lambda",3,"ASP A  19;ASN A  18;SER A 109","None","1.00A","3lsfB-1td0A:undetectable;3lsfE-1td0A:undetectable","3lsfB-1td0A:20.48;3lsfE-1td0A:20.48"],["4QZU_D_ACTD201_0","RETINOL-BINDING PROTEIN 2","1td0","HEAD DECORATION PROTEIN","Escherichia virus Lambda",3,"ASP A  95;HIS A  97;LYS A  99","None","0.94A","4qzuD-1td0A:undetectable","4qzuD-1td0A:15.89"],["5ZSF_A_6T0A910_0","TOLL-LIKE RECEPTOR 7","1td0","HEAD DECORATION PROTEIN","Escherichia virus Lambda",4,"THR A  82;ILE A  88;THR A  85;PHE A 103","None","0.99A","5zsfA-1td0A:0.0;5zsfB-1td0A:0.0","5zsfA-1td0A:17.59;5zsfB-1td0A:17.59"]]