SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1td6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 5 LEU A  88
VAL A  91
LEU A  95
GLN A  98
 None
 0.70A 1fbmE-1td6A:
undetectable		 1fbmE-1td6A:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 8 LEU A 145
PHE A 162
LEU A 129
ALA A 165
 None
 0.76A 1fiqC-1td6A:
undetectable		 1fiqC-1td6A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		3 / 3 LEU A  88
VAL A  91
LEU A  95
 None
 0.51A 1mz9B-1td6A:
undetectable		 1mz9B-1td6A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 7 ILE A 197
LEU A 236
PHE A   8
LEU A  71
 None
 0.95A 3adxA-1td6A:
undetectable		 3adxA-1td6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 8 LEU A 145
PHE A 162
LEU A 129
ALA A 165
 None
 0.81A 3uniB-1td6A:
undetectable		 3uniB-1td6A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		3 / 3 GLY A  37
THR A  41
ASN A  36
 None
 0.73A 3v4tD-1td6A:
undetectable		 3v4tD-1td6A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 8 GLU A 273
PHE A 207
ILE A 211
VAL A   9
 None
 0.98A 4dx7B-1td6A:
undetectable		 4dx7B-1td6A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		4 / 7 ILE A 197
ILE A 232
PHE A 160
LEU A 210
 None
 0.80A 5fukA-1td6A:
0.0
5fukB-1td6A:
0.5		 5fukA-1td6A:
21.36
5fukB-1td6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1td6 HYPOTHETICAL PROTEIN
MG237 HOMOLOG
(Mycoplasma
pneumoniae) 		5 / 12 LEU A 145
PHE A 160
LEU A  15
ILE A 169
LEU A 236
 None
 1.20A 5y2tA-1td6A:
undetectable		 5y2tA-1td6A:
undetectable