SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 8 GLY A 238
GLU A 235
PHE A 362
HIS A 360
 None
 0.95A 1ax9A-1tdkA:
undetectable		 1ax9A-1tdkA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 8 GLY A 239
GLU A 235
PHE A 362
HIS A 360
 None
 0.85A 1ax9A-1tdkA:
undetectable		 1ax9A-1tdkA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 12 ILE A 408
TYR A 357
VAL A 393
ILE A 327
SER A 415
 None
 1.20A 1fm4A-1tdkA:
undetectable		 1fm4A-1tdkA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 12 GLU A 167
TYR A 180
TYR A 188
GLY A 193
TYR A 183
 None
 1.08A 1httB-1tdkA:
2.9		 1httB-1tdkA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 12 PHE A  11
SER A 216
PHE A 438
TYR A 180
ILE A 176
 None
 1.17A 1kglA-1tdkA:
undetectable		 1kglA-1tdkA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 6 GLU A  93
LEU A  91
ARG A 232
PHE A 233
 None
 1.01A 1s8fB-1tdkA:
undetectable		 1s8fB-1tdkA:
15.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		7 / 7 ARG A  90
ASN A 208
HIS A 223
PHE A 227
TYR A 372
ILE A 430
TRP A 465
 LVG  A 491 (-3.5A)
LVG  A 487 (-3.9A)
LVG  A 487 (-2.5A)
LVG  A 487 (-3.9A)
LVG  A 491 ( 4.9A)
FAD  A 488 (-4.7A)
None
 0.23A 1tdnA-1tdkA:
64.2		 1tdnA-1tdkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 ARG A  90
HIS A 223
PHE A 227
ILE A 374
 LVG  A 491 (-3.5A)
LVG  A 487 (-2.5A)
LVG  A 487 (-3.9A)
LVG  A 491 ( 4.6A)
 0.91A 1tdnA-1tdkA:
64.2		 1tdnA-1tdkA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 ASN A 208
HIS A 223
PHE A 227
TYR A 356
 LVG  A 487 (-3.9A)
LVG  A 487 (-2.5A)
LVG  A 487 (-3.9A)
None
 1.41A 1tdnA-1tdkA:
64.2		 1tdnA-1tdkA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 12 LEU A 190
GLY A 198
ASP A 210
GLY A 204
TYR A 213
 None
 1.13A 1zz1C-1tdkA:
undetectable		 1zz1C-1tdkA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 GLY A 238
GLU A 235
PHE A 362
HIS A 360
 None
 0.90A 2ackA-1tdkA:
undetectable		 2ackA-1tdkA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 GLY A 239
GLU A 235
PHE A 362
HIS A 360
 None
 0.81A 2ackA-1tdkA:
undetectable		 2ackA-1tdkA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 LYS A 124
GLY A 198
PRO A 197
 None
 1.01A 2hreB-1tdkA:
undetectable		 2hreB-1tdkA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 MET A 207
TYR A 157
HIS A 223
GLY A 204
ILE A 203
 None
None
LVG  A 487 (-2.5A)
None
None
 1.48A 2zm7A-1tdkA:
0.0		 2zm7A-1tdkA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 MET A 207
TYR A 157
HIS A 223
GLY A 204
ILE A 203
 None
None
LVG  A 487 (-2.5A)
None
None
 1.49A 2zm8A-1tdkA:
0.0		 2zm8A-1tdkA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA512_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 MET A 207
TYR A 157
SER A 220
GLY A 204
ILE A 203
 None
 1.46A 2zm8A-1tdkA:
0.0		 2zm8A-1tdkA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 GLN A 114
PHE A 112
TYR A 356
 None
 0.94A 3ucjB-1tdkA:
undetectable		 3ucjB-1tdkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 GLN A 114
PHE A 112
TYR A 356
 None
 0.95A 3ucjA-1tdkA:
undetectable		 3ucjA-1tdkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 THR A 431
VAL A 319
GLU A 219
 None
 0.68A 3v4tA-1tdkA:
undetectable
3v4tD-1tdkA:
undetectable		 3v4tA-1tdkA:
22.10
3v4tD-1tdkA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 GLY A  45
ALA A 476
GLY A 473
VAL A  38
VAL A  51
 None
 1.22A 4c5lA-1tdkA:
3.0		 4c5lA-1tdkA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 GLY A  45
ALA A 476
GLY A 473
VAL A  38
VAL A  51
 None
 1.22A 4c5lD-1tdkA:
undetectable		 4c5lD-1tdkA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 GLY A  45
ALA A 476
GLY A 473
VAL A  38
VAL A  51
 None
 1.19A 4c5nB-1tdkA:
undetectable		 4c5nB-1tdkA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 GLY A  45
ALA A 476
GLY A 473
VAL A  38
VAL A  51
 None
 1.24A 4c5nD-1tdkA:
undetectable		 4c5nD-1tdkA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 LYS A 311
LYS A 312
PRO A 309
 None
 0.95A 4dv1L-1tdkA:
undetectable		 4dv1L-1tdkA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 PHE A 112
VAL A  98
ILE A 102
 None
 0.61A 4emaA-1tdkA:
undetectable		 4emaA-1tdkA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		3 / 3 LYS A 145
PRO A 146
SER A 147
 None
 0.36A 4k50I-1tdkA:
undetectable		 4k50I-1tdkA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 8 ALA A 455
GLY A 473
ALA A  48
GLY A  45
 None
 0.68A 4zjzA-1tdkA:
undetectable		 4zjzA-1tdkA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 VAL A 215
PHE A  11
ASN A   5
GLU A 209
ILE A 203
 None
 1.46A 4zvmA-1tdkA:
3.2
4zvmB-1tdkA:
3.5		 4zvmA-1tdkA:
17.58
4zvmB-1tdkA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 ALA A  49
ARG A  67
GLY A  70
THR A  74
 None
None
FAD  A 488 (-2.8A)
None
 0.91A 5bs8A-1tdkA:
undetectable
5bs8C-1tdkA:
undetectable
5bs8D-1tdkA:
undetectable		 5bs8A-1tdkA:
23.45
5bs8C-1tdkA:
23.45
5bs8D-1tdkA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 7 ALA A  49
ARG A  67
GLY A  70
THR A  74
 None
None
FAD  A 488 (-2.8A)
None
 0.91A 5bs8A-1tdkA:
undetectable
5bs8B-1tdkA:
undetectable
5bs8C-1tdkA:
undetectable		 5bs8A-1tdkA:
23.45
5bs8B-1tdkA:
20.45
5bs8C-1tdkA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 6 ALA A  49
ARG A  67
GLY A  70
THR A  74
 None
None
FAD  A 488 (-2.8A)
None
 0.93A 5btgA-1tdkA:
undetectable
5btgB-1tdkA:
1.8
5btgC-1tdkA:
0.0		 5btgA-1tdkA:
23.45
5btgB-1tdkA:
20.45
5btgC-1tdkA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 12 PHE A  11
SER A 216
PHE A 438
TYR A 180
ILE A 176
 None
 1.36A 5ljbA-1tdkA:
undetectable		 5ljbA-1tdkA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		4 / 5 ILE A 264
PHE A 304
ARG A 301
THR A 295
 None
None
None
FAD  A 488 ( 4.7A)
 1.26A 5z84N-1tdkA:
0.0
5z84W-1tdkA:
undetectable		 5z84N-1tdkA:
20.19
5z84W-1tdkA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 10 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.96A 6ebpD-1tdkA:
undetectable		 6ebpD-1tdkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.94A 6ebzA-1tdkA:
undetectable		 6ebzA-1tdkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.92A 6ebzB-1tdkA:
undetectable		 6ebzB-1tdkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.97A 6ebzC-1tdkA:
undetectable		 6ebzC-1tdkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.92A 6ebzD-1tdkA:
undetectable		 6ebzD-1tdkA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.90A 6gp2A-1tdkA:
undetectable		 6gp2A-1tdkA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1tdk L-AMINO ACID OXIDASE
(Gloydius
halys) 		5 / 11 PHE A 381
LEU A 384
ASP A 385
ILE A 327
ILE A 392
 None
 0.91A 6gp2B-1tdkA:
undetectable		 6gp2B-1tdkA:
11.63