SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 1tdq AGGRECAN CORE
PROTEIN
TENASCIN-R
(Rattus
norvegicus) 		4 / 6 LEU A 186
ILE B 103
ARG B  85
TYR A 162
 None
 1.12A 1db1A-1tdqA:
undetectable		 1db1A-1tdqA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 1tdq AGGRECAN CORE
PROTEIN
(Rattus
norvegicus) 		5 / 8 ILE B  41
ILE B  60
ILE B 103
ARG B  65
ASN B  63
 None
 1.24A 2nniA-1tdqB:
undetectable		 2nniA-1tdqB:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1tdq AGGRECAN CORE
PROTEIN
(Rattus
norvegicus) 		4 / 6 GLN B  80
PHE B  81
LEU B  62
PHE B  71
 None
 1.17A 3ablP-1tdqB:
undetectable
3ablW-1tdqB:
undetectable		 3ablP-1tdqB:
14.23
3ablW-1tdqB:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		3 / 3 ARG A  69
GLU A  71
THR A  88
 None
 0.90A 3v4tA-1tdqA:
0.0		 3v4tA-1tdqA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		5 / 6 PHE A  90
ALA A  20
PRO A  66
LEU A  64
THR A  18
 None
 1.42A 4dtzA-1tdqA:
undetectable		 4dtzA-1tdqA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		4 / 5 GLU A 113
THR A 149
HIS A 137
LEU A 153
 None
 1.15A 5axaA-1tdqA:
undetectable		 5axaA-1tdqA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		4 / 5 GLU A 113
THR A 149
HIS A 137
LEU A 153
 None
 1.22A 5axaC-1tdqA:
undetectable		 5axaC-1tdqA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1tdq TENASCIN-R
AGGRECAN CORE
PROTEIN
(Rattus
norvegicus;
Rattus
norvegicus) 		3 / 3 ASP B 112
GLU B  82
SER A 129
 CA  B 127 (-2.9A)
None
None
 0.76A 5bw4B-1tdqB:
undetectable		 5bw4B-1tdqB:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		5 / 9 VAL A 164
LEU A 112
THR A 151
THR A 152
TRP A 114
 None
 1.47A 5jn8C-1tdqA:
undetectable		 5jn8C-1tdqA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		5 / 12 GLY A 163
ASN A 181
ALA A 178
VAL A 126
TYR A 128
 None
 1.28A 5kbwB-1tdqA:
undetectable		 5kbwB-1tdqA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		5 / 10 VAL A 164
LEU A 112
THR A 151
THR A 152
TRP A 114
 None
 1.47A 5ku6B-1tdqA:
undetectable		 5ku6B-1tdqA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		5 / 9 VAL A 164
LEU A 112
THR A 151
THR A 152
TRP A 114
 None
 1.49A 5ku6C-1tdqA:
undetectable		 5ku6C-1tdqA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 1tdq TENASCIN-R
(Rattus
norvegicus) 		4 / 8 THR A  49
TYR A  38
TRP A  24
LEU A  52
 None
 1.31A 6cnjD-1tdqA:
1.5
6cnjE-1tdqA:
2.5		 6cnjD-1tdqA:
15.23
6cnjE-1tdqA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tdq AGGRECAN CORE
PROTEIN
(Rattus
norvegicus) 		4 / 6 GLN B  80
PHE B  81
LEU B  62
PHE B  71
 None
 1.19A 6nmpC-1tdqB:
undetectable
6nmpJ-1tdqB:
undetectable		 6nmpC-1tdqB:
14.23
6nmpJ-1tdqB:
18.10