SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1te2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		3 / 3 VAL A  57
VAL A  76
TRP A  61
 None
 0.94A 1bdwA-1te2A:
undetectable
1bdwB-1te2A:
undetectable		 1bdwA-1te2A:
8.77
1bdwB-1te2A:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		4 / 8 ALA A 100
GLU A  99
LEU A  93
LEU A 171
 None
 0.90A 1ereE-1te2A:
undetectable		 1ereE-1te2A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		4 / 8 ALA A 100
GLU A  99
LEU A  93
LEU A 171
 None
 0.90A 1ereF-1te2A:
undetectable		 1ereF-1te2A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		4 / 4 LEU A 113
SER A 147
ASP A  15
ASP A  20
 None
PGA  A 711 ( 4.8A)
PGA  A 711 ( 3.6A)
None
 1.47A 2br4B-1te2A:
3.3		 2br4B-1te2A:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		3 / 3 ARG A 201
ASP A 173
ASN A 176
 None
CA  A 702 (-2.9A)
None
 0.67A 2zzmA-1te2A:
2.1		 2zzmA-1te2A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		5 / 12 GLY A  51
ILE A  54
VAL A  76
ASP A  55
MET A 121
 PGA  A 711 (-3.3A)
None
None
None
None
 1.07A 4a81A-1te2A:
undetectable		 4a81A-1te2A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		4 / 6 ALA A 158
LEU A 155
VAL A 153
GLU A 172
 None
None
None
PGA  A 711 ( 4.4A)
 0.91A 4g24A-1te2A:
2.3		 4g24A-1te2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		4 / 8 LEU A 215
VAL A 207
VAL A 191
LEU A 220
 None
 1.01A 4puoC-1te2A:
undetectable		 4puoC-1te2A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		5 / 8 LEU A 161
VAL A 163
ILE A   7
ALA A  10
LEU A 109
 None
 1.18A 4qrcA-1te2A:
undetectable		 4qrcA-1te2A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		3 / 3 ASP A  13
LEU A  50
GLY A  51
 PGA  A 711 ( 2.4A)
None
PGA  A 711 (-3.3A)
 0.48A 4xmfA-1te2A:
undetectable		 4xmfA-1te2A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE
(Escherichia
coli) 		4 / 4 ASP A 173
ILE A  19
PRO A  92
LEU A  94
 CA  A 702 (-2.9A)
None
None
None
 1.10A 6mkeA-1te2A:
undetectable		 6mkeA-1te2A:
13.79