SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1te5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  16
PHE A  18
GLN A  66
ILE A  79
LEU A 208
 None
 1.20A 1dhfB-1te5A:
undetectable		 1dhfB-1te5A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 4 VAL A 245
TRP A 180
TRP A 244
 None
 1.39A 1gmkA-1te5A:
undetectable
1gmkB-1te5A:
undetectable		 1gmkA-1te5A:
7.88
1gmkB-1te5A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  54
ASP A  35
GLY A  28
PRO A  32
 None
 0.93A 2aohA-1te5A:
undetectable		 2aohA-1te5A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 244
GLN A 239
TRP A 248
 None
 1.15A 2vqyA-1te5A:
undetectable		 2vqyA-1te5A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 248
VAL A 252
TRP A 180
 None
 0.99A 2xdcC-1te5A:
undetectable
2xdcD-1te5A:
undetectable		 2xdcC-1te5A:
7.88
2xdcD-1te5A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 248
VAL A 252
TRP A 180
 None
 1.05A 2xdcE-1te5A:
undetectable
2xdcF-1te5A:
undetectable		 2xdcE-1te5A:
7.88
2xdcF-1te5A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 248
VAL A 252
TRP A 180
 None
 0.99A 2y5mE-1te5A:
undetectable
2y5mF-1te5A:
undetectable		 2y5mE-1te5A:
7.88
2y5mF-1te5A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 248
VAL A 252
TRP A 180
 None
 0.98A 2y6nC-1te5A:
undetectable
2y6nD-1te5A:
undetectable		 2y6nC-1te5A:
7.88
2y6nD-1te5A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 248
VAL A 252
TRP A 180
 None
 0.97A 2y6nE-1te5A:
undetectable
2y6nF-1te5A:
undetectable		 2y6nE-1te5A:
7.88
2y6nF-1te5A:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 PHE A 134
TYR A  42
GLU A 147
ASP A 179
GLY A 100
 None
 1.30A 4qb9F-1te5A:
undetectable		 4qb9F-1te5A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 184
ARG A 166
ASP A 163
ILE A 159
 None
 1.13A 5a06B-1te5A:
undetectable		 5a06B-1te5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 221
THR A 193
ARG A 195
 None
 0.74A 5b2sB-1te5A:
undetectable		 5b2sB-1te5A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 221
THR A 193
ARG A 195
 None
 0.78A 5b2tB-1te5A:
undetectable		 5b2tB-1te5A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 SER A  72
GLU A  73
GLY A  38
GLY A  77
 None
 0.83A 5cdnA-1te5A:
undetectable
5cdnB-1te5A:
undetectable		 5cdnA-1te5A:
19.57
5cdnB-1te5A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 SER A  72
GLU A  73
GLY A  38
GLY A  77
 None
 0.85A 5cdnR-1te5A:
undetectable
5cdnS-1te5A:
undetectable		 5cdnR-1te5A:
19.57
5cdnS-1te5A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 1te5 CONSERVED
HYPOTHETICAL PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 ASN A 109
SER A 187
SER A 186
 None
 0.76A 5gsnA-1te5A:
undetectable		 5gsnA-1te5A:
22.25