SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 188
GLU A 192
TRP A 195
THR A 106
 None
 1.32A 1qvuA-1texA:
0.3		 1qvuA-1texA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ILE A  86
PHE A  38
ARG A 129
LEU A 116
 None
 0.90A 3ablN-1texA:
undetectable
3ablW-1texA:
undetectable		 3ablN-1texA:
18.62
3ablW-1texA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ILE A  86
PHE A  38
ARG A 129
LEU A 116
 None
 0.89A 3abmN-1texA:
undetectable
3abmW-1texA:
undetectable		 3abmN-1texA:
18.62
3abmW-1texA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 PRO A 117
LEU A 116
ARG A 112
 None
 0.85A 3aqiB-1texA:
undetectable		 3aqiB-1texA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ASP A 130
SER A 126
GLY A 121
ASP A 118
 None
 1.40A 3w9tB-1texA:
undetectable		 3w9tB-1texA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ASP A 130
SER A 126
GLY A 121
ASP A 118
 None
 1.40A 3w9tC-1texA:
undetectable		 3w9tC-1texA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ASP A 130
SER A 126
GLY A 121
ASP A 118
 None
 1.40A 3w9tD-1texA:
undetectable		 3w9tD-1texA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A   9
LEU A  11
THR A 106
TRP A 103
 None
 1.24A 4do3A-1texA:
undetectable		 4do3A-1texA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ARG A  26
VAL A 222
LEU A 229
VAL A  96
GLY A  99
 None
 1.41A 5i8fA-1texA:
0.0		 5i8fA-1texA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 GLN A 105
THR A 106
LEU A 138
LEU A  11
 TRE  A 501 (-4.6A)
None
None
None
 1.32A 5m5kB-1texA:
undetectable		 5m5kB-1texA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 VAL A 132
LEU A   9
LEU A 138
LEU A 124
 None
 1.08A 6f6sA-1texA:
undetectable
6f6sB-1texA:
undetectable		 6f6sA-1texA:
15.52
6f6sB-1texA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 1tex STF0
SULFOTRANSFERASE
(Mycolicibacteriu
m
smegmatis) 		4 / 4 PRO A 136
LEU A   9
VAL A 131
ARG A 129
 None
 1.37A 6fgdA-1texA:
2.4		 6fgdA-1texA:
21.03