SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.83A 1a7yA-1tf1A:
undetectable		 1a7yA-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.83A 1a7yB-1tf1A:
undetectable		 1a7yB-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 THR A 120
GLU A 125
THR A 100
HIS A  67
 None
 1.34A 1d4fA-1tf1A:
undetectable		 1d4fA-1tf1A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 THR A 120
GLU A 125
THR A 100
HIS A  67
 None
 1.34A 1d4fC-1tf1A:
undetectable		 1d4fC-1tf1A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 THR A 120
GLU A 125
THR A 100
HIS A  67
 None
 1.41A 1d4fD-1tf1A:
undetectable		 1d4fD-1tf1A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 MET A  11
LEU A  14
SER A  15
 None
 0.61A 1ee2A-1tf1A:
undetectable		 1ee2A-1tf1A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.86A 1i3wE-1tf1A:
undetectable		 1i3wE-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.84A 1i3wE-1tf1A:
undetectable		 1i3wE-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.79A 1i3wF-1tf1A:
undetectable		 1i3wF-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.87A 1i3wG-1tf1A:
undetectable		 1i3wG-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.83A 1i3wG-1tf1A:
undetectable		 1i3wG-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.85A 1i3wH-1tf1A:
undetectable		 1i3wH-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.81A 1mnvD-1tf1A:
undetectable		 1mnvD-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.74A 1mnvD-1tf1A:
undetectable		 1mnvD-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.87A 1ovfB-1tf1A:
undetectable		 1ovfB-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.80A 1qfiA-1tf1A:
undetectable		 1qfiA-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 10 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 0.96A 1sdtA-1tf1A:
undetectable		 1sdtA-1tf1A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 PRO A  65
ILE A 133
GLY A  72
ALA A  68
ALA A  35
 None
 1.17A 1sg9C-1tf1A:
undetectable		 1sg9C-1tf1A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.85A 1unjF-1tf1A:
undetectable		 1unjF-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.83A 1unjF-1tf1A:
undetectable		 1unjF-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.85A 1unjR-1tf1A:
undetectable		 1unjR-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A  99
THR A 100
PRO A  98
 None
 0.83A 1unjR-1tf1A:
undetectable		 1unjR-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 ILE A  36
ALA A 147
LEU A  75
ALA A  74
LEU A  14
 None
 1.14A 1xdkA-1tf1A:
undetectable		 1xdkA-1tf1A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 7 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 1.11A 2aojB-1tf1A:
undetectable		 2aojB-1tf1A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 8 ASP A 122
LEU A 130
LEU A  64
LEU A  44
 None
 0.92A 2bfpC-1tf1A:
undetectable		 2bfpC-1tf1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 8 ASP A 122
LEU A 130
LEU A  64
LEU A  44
 None
 0.94A 2bfpD-1tf1A:
undetectable		 2bfpD-1tf1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 ALA A  74
GLY A  70
GLY A  61
LEU A  44
LEU A  60
 None
 1.08A 2hw2A-1tf1A:
undetectable		 2hw2A-1tf1A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 0.93A 2r5pA-1tf1A:
undetectable		 2r5pA-1tf1A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 0.93A 2r5pC-1tf1A:
undetectable		 2r5pC-1tf1A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 9 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 1.14A 3d1yB-1tf1A:
undetectable		 3d1yB-1tf1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 GLN A 113
THR A 120
GLU A 125
THR A 100
 None
 1.45A 3glqA-1tf1A:
undetectable		 3glqA-1tf1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 THR A 120
GLU A 125
THR A 100
HIS A  67
 None
 1.15A 3glqA-1tf1A:
undetectable		 3glqA-1tf1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 THR A 120
GLU A 125
THR A 100
HIS A  67
 None
 1.24A 3glqB-1tf1A:
undetectable		 3glqB-1tf1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 LEU A 108
GLN A 113
LEU A 111
GLU A 112
 None
 1.08A 3h5gA-1tf1A:
undetectable
3h5gB-1tf1A:
undetectable		 3h5gA-1tf1A:
13.74
3h5gB-1tf1A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 5 THR A 120
GLU A 125
THR A 100
HIS A  67
 None
 1.27A 3n58A-1tf1A:
undetectable		 3n58A-1tf1A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		4 / 7 ILE A 137
LEU A 180
ALA A 146
ALA A  17
 None
 0.77A 4g77A-1tf1A:
undetectable		 4g77A-1tf1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
PRO A  98
THR A  99
 None
 0.81A 4hivD-1tf1A:
undetectable		 4hivD-1tf1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 LEU A 111
GLU A 124
GLY A  70
ALA A  74
PHE A 162
 None
 1.17A 4hytA-1tf1A:
undetectable		 4hytA-1tf1A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 LEU A 111
GLU A 124
GLY A  70
ALA A  74
PHE A 162
 None
 1.17A 4hytC-1tf1A:
undetectable		 4hytC-1tf1A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 LEU A 111
GLU A 124
GLY A  70
ALA A  74
PHE A 162
 None
 1.30A 4xe5A-1tf1A:
undetectable		 4xe5A-1tf1A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 11 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 1.05A 5kr2B-1tf1A:
undetectable		 5kr2B-1tf1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 9 LEU A 180
GLY A  46
ILE A  45
VAL A  16
ILE A 176
 None
 1.05A 5kr2D-1tf1A:
undetectable		 5kr2D-1tf1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 8 VAL A  13
ILE A 176
ALA A 173
VAL A 144
VAL A 145
 None
 1.44A 5l94A-1tf1A:
undetectable		 5l94A-1tf1A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		3 / 3 THR A 100
THR A  91
LEU A  76
 None
 0.70A 5m66D-1tf1A:
undetectable		 5m66D-1tf1A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 12 ALA A  71
ILE A  45
GLY A  46
THR A  31
LEU A  66
 None
 1.00A 5nfjA-1tf1A:
undetectable		 5nfjA-1tf1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 11 SER A 135
TYR A 138
GLY A 181
ALA A 184
VAL A  13
 None
 1.30A 6hu9A-1tf1A:
undetectable
6hu9E-1tf1A:
undetectable
6hu9I-1tf1A:
undetectable		 6hu9A-1tf1A:
18.33
6hu9E-1tf1A:
22.49
6hu9I-1tf1A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1tf1 NEGATIVE REGULATOR
OF ALLANTOIN AND
GLYOXYLATE
UTILIZATION OPERONS
(Escherichia
coli) 		5 / 10 SER A 135
TYR A 138
GLY A 181
ALA A 184
VAL A  13
 None
 1.29A 6hu9L-1tf1A:
0.0
6hu9P-1tf1A:
0.0
6hu9T-1tf1A:
0.0		 6hu9L-1tf1A:
18.33
6hu9P-1tf1A:
22.49
6hu9T-1tf1A:
15.66