SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tfp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 115
SER A 117
THR A 119
 None
 0.44A 1dvxA-1tfpA:
19.9		 1dvxA-1tfpA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.44A 1dvxB-1tfpA:
19.3		 1dvxB-1tfpA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 5 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.44A 1eta1-1tfpA:
18.8		 1eta1-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 5 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.45A 1eta2-1tfpA:
17.9		 1eta2-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 6 MET A  13
LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.50A 1etb1-1tfpA:
19.5		 1etb1-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 6 LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
 None
 0.49A 1etb2-1tfpA:
18.8		 1etb2-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.49A 1f86B-1tfpA:
19.0		 1f86B-1tfpA:
77.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		7 / 11 LEU A  17
GLU A  54
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.65A 1ictA-1tfpA:
19.5
1ictC-1tfpA:
19.5		 1ictA-1tfpA:
73.85
1ictC-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 11 LYS A  15
LEU A  17
GLU A  54
LEU A 110
SER A 117
VAL A 121
 None
 0.91A 1ictA-1tfpA:
19.5
1ictC-1tfpA:
19.5		 1ictA-1tfpA:
73.85
1ictC-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.78A 1ictB-1tfpA:
19.2		 1ictB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.77A 1ictB-1tfpA:
19.2		 1ictB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LEU A  17
THR A 106
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.52A 1ictD-1tfpA:
19.5		 1ictD-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 10 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.49A 1ie4A-1tfpA:
19.4
1ie4C-1tfpA:
19.2		 1ie4A-1tfpA:
76.92
1ie4C-1tfpA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 10 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.57A 1ie4A-1tfpA:
19.4
1ie4C-1tfpA:
19.2		 1ie4A-1tfpA:
76.92
1ie4C-1tfpA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 8 LYS A  15
GLU A  54
ALA A 108
LEU A 110
 None
 0.52A 1ie4B-1tfpA:
19.4
1ie4D-1tfpA:
19.4		 1ie4B-1tfpA:
76.92
1ie4D-1tfpA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 8 LYS A  15
GLU A  54
ALA A 108
THR A 119
 None
 0.69A 1ie4B-1tfpA:
19.4
1ie4D-1tfpA:
19.4		 1ie4B-1tfpA:
76.92
1ie4D-1tfpA:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 7 LYS A  15
LEU A  17
GLU A  54
ALA A 108
 None
 0.23A 1sn0B-1tfpA:
18.8
1sn0D-1tfpA:
19.0		 1sn0B-1tfpA:
62.31
1sn0D-1tfpA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 9 MET A  13
LYS A  15
LEU A  17
GLU A  54
ALA A 108
 None
 0.36A 1sn0A-1tfpA:
18.6
1sn0C-1tfpA:
18.4		 1sn0A-1tfpA:
62.31
1sn0C-1tfpA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 6 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
VAL A 121
 None
 0.37A 1sn5A-1tfpA:
18.7		 1sn5A-1tfpA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		8 / 8 MET A  13
LYS A  15
LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.42A 1sn5C-1tfpA:
18.4		 1sn5C-1tfpA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 12 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
VAL A 121
 None
 0.35A 1sn5B-1tfpA:
18.9
1sn5D-1tfpA:
19.1		 1sn5B-1tfpA:
62.31
1sn5D-1tfpA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 12 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
VAL A 121
 None
 0.39A 1sn5B-1tfpA:
18.9
1sn5D-1tfpA:
19.1		 1sn5B-1tfpA:
62.31
1sn5D-1tfpA:
62.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		3 / 3 LEU A  17
LEU A 110
SER A 117
 None
 0.49A 1tlmA-1tfpA:
18.8		 1tlmA-1tfpA:
74.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 4 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.94A 1tt6A-1tfpA:
19.1		 1tt6A-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.69A 1tt6B-1tfpA:
19.8		 1tt6B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 5 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 1.02A 1tt6B-1tfpA:
19.8		 1tt6B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.47A 1tyrA-1tfpA:
18.7		 1tyrA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		7 / 7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
VAL A 121
 None
 0.62A 1tyrB-1tfpA:
18.0		 1tyrB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 11 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.69A 1tz8A-1tfpA:
19.2
1tz8B-1tfpA:
19.4		 1tz8A-1tfpA:
73.85
1tz8B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 11 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.77A 1tz8A-1tfpA:
19.2
1tz8B-1tfpA:
19.4		 1tz8A-1tfpA:
73.85
1tz8B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.47A 1tz8C-1tfpA:
19.6
1tz8D-1tfpA:
19.7		 1tz8C-1tfpA:
73.85
1tz8D-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.86A 1tz8C-1tfpA:
19.6
1tz8D-1tfpA:
19.7		 1tz8C-1tfpA:
73.85
1tz8D-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 4 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.55A 1tz8D-1tfpA:
19.7		 1tz8D-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.36A 2roxA-1tfpA:
19.4		 2roxA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 6 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
THR A 119
 None
 0.62A 2roxB-1tfpA:
18.8		 2roxB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.50A 3cfqA-1tfpA:
19.7		 3cfqA-1tfpA:
77.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.67A 3cfqA-1tfpA:
19.7		 3cfqA-1tfpA:
77.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.53A 3cfqA-1tfpA:
19.7
3cfqB-1tfpA:
19.0		 3cfqA-1tfpA:
77.97
3cfqB-1tfpA:
77.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 7 LEU A  17
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.34A 3d2tA-1tfpA:
19.8		 3d2tA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.93A 3d2tA-1tfpA:
19.8		 3d2tA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.42A 3d2tB-1tfpA:
18.7		 3d2tB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
ALA A 108
LEU A 110
THR A 119
 None
 0.96A 3d2tB-1tfpA:
18.7		 3d2tB-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 11 ALA A 109
VAL A  71
ILE A  55
LEU A  58
THR A 118
 None
 1.22A 3fl9C-1tfpA:
undetectable		 3fl9C-1tfpA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 9 ALA A 109
VAL A  71
ILE A  55
LEU A  58
THR A 118
 None
 1.22A 3fl9H-1tfpA:
undetectable		 3fl9H-1tfpA:
17.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		8 / 9 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.60A 3ozkA-1tfpA:
19.8		 3ozkA-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		7 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.45A 3ozkB-1tfpA:
19.7		 3ozkB-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.32A 4d7bB-1tfpA:
19.6		 4d7bB-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 1.02A 4d7bB-1tfpA:
19.6		 4d7bB-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.67A 4d7bA-1tfpA:
19.6		 4d7bA-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.97A 4d7bA-1tfpA:
19.6		 4d7bA-1tfpA:
73.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.68A 4i89A-1tfpA:
19.8		 4i89A-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.89A 4i89A-1tfpA:
19.8		 4i89A-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 8 LEU A  17
GLU A  54
THR A 106
ALA A 108
LEU A 110
 None
 0.78A 4iizB-1tfpA:
18.9		 4iizB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 8 LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.60A 4iizB-1tfpA:
18.9		 4iizB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 8 LYS A  15
LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.98A 4iizB-1tfpA:
18.9		 4iizB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 8 MET A  13
THR A 106
ALA A 108
VAL A 121
 None
 0.68A 4iizB-1tfpA:
18.9		 4iizB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 8 LEU A  17
GLU A  54
ALA A 108
LEU A 110
 None
 0.74A 4ik6B-1tfpA:
18.9		 4ik6B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 8 LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.54A 4ik6B-1tfpA:
18.9		 4ik6B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
THR A 106
ALA A 108
THR A 119
VAL A 121
 None
 0.66A 4ik7A-1tfpA:
19.6		 4ik7A-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		7 / 8 LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
THR A 119
VAL A 121
 None
 0.48A 4ik7B-1tfpA:
19.1		 4ik7B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		7 / 8 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
VAL A 121
 None
 0.50A 4ik7B-1tfpA:
19.1		 4ik7B-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		3 / 3 LYS A  15
LEU A  17
ALA A 108
 None
 0.33A 4ikiA-1tfpA:
19.7		 4ikiA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.52A 4ikiB-1tfpA:
19.0		 4ikiB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.60A 4ikjA-1tfpA:
19.7
4ikjB-1tfpA:
19.1		 4ikjA-1tfpA:
73.85
4ikjB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 8 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.47A 4ikjA-1tfpA:
19.7
4ikjB-1tfpA:
19.1		 4ikjA-1tfpA:
73.85
4ikjB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 8 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.64A 4ikkA-1tfpA:
19.6
4ikkB-1tfpA:
19.1		 4ikkA-1tfpA:
73.85
4ikkB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.47A 4ikkA-1tfpA:
19.6
4ikkB-1tfpA:
19.1		 4ikkA-1tfpA:
73.85
4ikkB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.78A 4iklA-1tfpA:
19.9
4iklB-1tfpA:
19.2		 4iklA-1tfpA:
73.85
4iklB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 8 LEU A  17
ALA A 108
LEU A 110
SER A 117
THR A 119
 None
 0.44A 4iklA-1tfpA:
19.9
4iklB-1tfpA:
19.2		 4iklA-1tfpA:
73.85
4iklB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 8 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.42A 4iklA-1tfpA:
19.9
4iklB-1tfpA:
19.2		 4iklA-1tfpA:
73.85
4iklB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.83A 4pwjA-1tfpA:
19.4		 4pwjA-1tfpA:
72.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
 None
 0.46A 4pwjA-1tfpA:
19.4		 4pwjA-1tfpA:
72.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 7 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.79A 4pwjB-1tfpA:
19.2		 4pwjB-1tfpA:
72.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
 None
 0.42A 4pwjB-1tfpA:
19.2		 4pwjB-1tfpA:
72.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LEU A  17
ALA A 108
LEU A 110
SER A 117
VAL A 121
 None
 0.45A 5a6iA-1tfpA:
20.1		 5a6iA-1tfpA:
72.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.82A 5a6iA-1tfpA:
20.1		 5a6iA-1tfpA:
72.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.72A 5bojA-1tfpA:
19.6		 5bojA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 0.89A 5bojA-1tfpA:
19.6		 5bojA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		6 / 7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
THR A 119
 None
 0.65A 5bojB-1tfpA:
18.9		 5bojB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		5 / 5 LYS A  15
LEU A  17
ALA A 108
LEU A 110
VAL A 121
 None
 0.44A 5cr1A-1tfpA:
19.7		 5cr1A-1tfpA:
78.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.33A 5l4iA-1tfpA:
19.6		 5l4iA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.84A 5l4iA-1tfpA:
19.6		 5l4iA-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LEU A  17
ALA A 108
LEU A 110
THR A 119
 None
 0.33A 5l4iB-1tfpA:
18.8		 5l4iB-1tfpA:
73.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 LYS A  15
LEU A  17
LEU A 110
SER A 117
 None
 1.11A 5l4iB-1tfpA:
18.8		 5l4iB-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 6 GLU A  89
PHE A  73
THR A 118
TYR A 116
 None
 1.32A 5lrbA-1tfpA:
undetectable		 5lrbA-1tfpA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 8 VAL A  71
VAL A  32
LEU A  58
THR A  59
 None
 0.77A 5tt3F-1tfpA:
undetectable		 5tt3F-1tfpA:
18.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.18A 6gnrA-1tfpA:
18.7		 6gnrA-1tfpA:
61.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 1tfp TRANSTHYRETIN
(Gallus
gallus) 		4 / 4 LYS A  15
LEU A  17
ALA A 108
LEU A 110
 None
 0.21A 6gnrB-1tfpA:
18.9		 6gnrB-1tfpA:
61.19