SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tg5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.79A 1a7yA-1tg5A:
undetectable		 1a7yA-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.88A 1a7yB-1tg5A:
undetectable		 1a7yB-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.80A 1i3wE-1tg5A:
undetectable		 1i3wE-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.84A 1i3wE-1tg5A:
undetectable		 1i3wE-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.77A 1i3wF-1tg5A:
undetectable		 1i3wF-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.83A 1i3wG-1tg5A:
undetectable		 1i3wG-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.83A 1i3wG-1tg5A:
undetectable		 1i3wG-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.84A 1i3wH-1tg5A:
undetectable		 1i3wH-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IHI_A_IU5A326_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 VAL A 169
TYR A 171
HIS A  27
ILE A  99
LEU A  68
 None
 1.24A 1ihiA-1tg5A:
0.0		 1ihiA-1tg5A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.81A 1mnvD-1tg5A:
undetectable		 1mnvD-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.74A 1mnvD-1tg5A:
undetectable		 1mnvD-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.84A 1ovfB-1tg5A:
undetectable		 1ovfB-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 8 GLY A 345
GLU A 343
SER A 316
ILE A 359
 None
 0.76A 1pk7B-1tg5A:
undetectable		 1pk7B-1tg5A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.77A 1qfiA-1tg5A:
undetectable		 1qfiA-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.83A 1unjF-1tg5A:
undetectable		 1unjF-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.78A 1unjF-1tg5A:
undetectable		 1unjF-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.86A 1unjL-1tg5A:
undetectable		 1unjL-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.82A 1unjR-1tg5A:
undetectable		 1unjR-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.87A 1unjX-1tg5A:
undetectable		 1unjX-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.87A 1unmF-1tg5A:
undetectable		 1unmF-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  94
THR A  95
PRO A  93
 None
 0.83A 1unmF-1tg5A:
undetectable		 1unmF-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 ILE A  29
ARG A 377
LEU A  47
ILE A 374
PHE A  31
 None
 1.45A 1y0xX-1tg5A:
undetectable		 1y0xX-1tg5A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 6 GLY A 184
SER A  55
LEU A 149
ILE A  99
HIS A  64
 None
 1.37A 1yajF-1tg5A:
undetectable		 1yajF-1tg5A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 4 GLY A 184
SER A  55
ILE A  99
HIS A  64
 None
 1.13A 1yajJ-1tg5A:
undetectable		 1yajJ-1tg5A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 PRO A 318
ILE A 359
GLY A 345
TYR A 322
 None
 1.13A 2jkjD-1tg5A:
undetectable		 2jkjD-1tg5A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 PRO A 318
ILE A 359
GLY A 345
TYR A 322
 None
 1.13A 2jkjF-1tg5A:
undetectable		 2jkjF-1tg5A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 GLY A 208
GLN A 286
HIS A 287
VAL A 121
VAL A 118
 None
645  A 501 (-3.4A)
FE2  A 500 ( 3.4A)
None
None
 1.38A 3fhjB-1tg5A:
undetectable		 3fhjB-1tg5A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 THR A  95
PRO A  93
THR A  94
 None
 0.86A 4hivD-1tg5A:
undetectable		 4hivD-1tg5A:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 8 VAL A 169
TYR A 171
HIS A  27
ILE A  99
LEU A  68
 None
 1.18A 4jq1B-1tg5A:
undetectable		 4jq1B-1tg5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQA_A_ID8A401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 VAL A 169
TYR A 171
HIS A  27
ILE A  99
LEU A  68
 None
 1.20A 4jqaA-1tg5A:
0.0		 4jqaA-1tg5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQA_B_ID8B401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 VAL A 169
TYR A 171
HIS A  27
ILE A  99
LEU A  68
 None
 1.18A 4jqaB-1tg5A:
0.0		 4jqaB-1tg5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 VAL A 169
TYR A 171
HIS A  27
ILE A  99
LEU A  68
 None
 1.31A 4jtqA-1tg5A:
undetectable		 4jtqA-1tg5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_B_FLPB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 VAL A 169
TYR A 171
HIS A  27
ILE A  99
LEU A  68
 None
 1.19A 4jtqB-1tg5A:
0.0		 4jtqB-1tg5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 8 TYR A 168
VAL A  23
LEU A 160
LEU A 258
 None
 1.04A 4jtrA-1tg5A:
undetectable		 4jtrA-1tg5A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 MET A  49
SER A  71
ARG A 202
ILE A 375
LEU A 203
 None
 1.42A 4xk8B-1tg5A:
undetectable		 4xk8B-1tg5A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		6 / 12 GLY A 117
PHE A  31
LEU A  47
ILE A 372
THR A 361
GLY A 365
 None
 1.48A 5hieA-1tg5A:
undetectable		 5hieA-1tg5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 5 GLU A 373
GLY A 399
ARG A 377
GLY A 396
 645  A 501 ( 2.8A)
645  A 501 (-4.2A)
None
None
 1.01A 5kprA-1tg5A:
undetectable		 5kprA-1tg5A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 116
ILE A 374
THR A 361
ILE A 370
LEU A  47
 None
 1.09A 5ljdA-1tg5A:
0.0		 5ljdA-1tg5A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 10 MET A  49
SER A  71
ARG A 202
ILE A 375
LEU A 203
 None
 1.31A 5oy0b-1tg5A:
undetectable		 5oy0b-1tg5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  39
THR A  79
PHE A 185
THR A  59
SER A  98
 None
 1.25A 5xipA-1tg5A:
undetectable		 5xipA-1tg5A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_C_HFGC1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		5 / 12 VAL A  39
THR A  79
PHE A 185
THR A  59
SER A  98
 None
 1.37A 5xiqC-1tg5A:
undetectable		 5xiqC-1tg5A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 7 ILE A 200
PHE A  43
LEU A  47
ILE A 346
 None
 0.88A 6b5vA-1tg5A:
undetectable
6b5vB-1tg5A:
undetectable		 6b5vA-1tg5A:
10.86
6b5vB-1tg5A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		3 / 3 ILE A 155
THR A 154
PRO A 100
 None
 0.58A 6ncsA-1tg5A:
undetectable		 6ncsA-1tg5A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE
(Arabidopsis
thaliana) 		4 / 6 ILE A 370
LEU A 364
ARG A 119
THR A  79
 None
 1.08A 6nmfN-1tg5A:
undetectable
6nmfW-1tg5A:
undetectable		 6nmfN-1tg5A:
21.26
6nmfW-1tg5A:
9.44