SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1th7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
1th7 SMALL NUCLEAR
RIBOPROTEIN PROTEIN

(Sulfolobus
solfataricus)
4 / 5 LEU A  45
ILE A  65
SER A  50
GLY A  34
None
0.98A 2otfA-1th7A:
undetectable
2otfA-1th7A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)
1th7 SMALL NUCLEAR
RIBOPROTEIN PROTEIN

(Sulfolobus
solfataricus)
4 / 8 GLY A  69
ASN A  44
MET A   3
ILE A  75
None
0.92A 4j4vC-1th7A:
undetectable
4j4vC-1th7A:
17.87