SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1thg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 8 GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.64A 1ax9A-1thgA:
37.3		 1ax9A-1thgA:
31.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		3 / 3 LEU A 313
PRO A 314
LEU A 317
 None
 0.51A 1hrkA-1thgA:
3.6		 1hrkA-1thgA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 5 TYR A 273
PRO A 168
LEU A 172
THR A 278
 None
 1.25A 1i2wA-1thgA:
undetectable		 1i2wA-1thgA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 8 GLY A 215
GLY A 464
LEU A 467
GLY A 131
 None
 0.75A 1jhaA-1thgA:
2.0		 1jhaA-1thgA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 5 SER A 137
SER A 138
VAL A  99
PHE A  57
 None
 1.20A 1oipA-1thgA:
1.9		 1oipA-1thgA:
20.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 130
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.61A 1qtiA-1thgA:
37.3		 1qtiA-1thgA:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 130
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.82A 1qtiA-1thgA:
37.3		 1qtiA-1thgA:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 131
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.88A 1qtiA-1thgA:
37.3		 1qtiA-1thgA:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 11 ASP A 353
GLY A 464
SER A 217
PHE A 133
PHE A 358
 None
 1.28A 1w76A-1thgA:
37.2		 1w76A-1thgA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 10 ASP A 353
GLY A 464
SER A 217
PHE A 133
PHE A 358
 None
 1.27A 1w76B-1thgA:
37.2		 1w76B-1thgA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 10 GLY A 130
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.54A 1w76B-1thgA:
37.2		 1w76B-1thgA:
31.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 10 GLY A 131
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.79A 1w76B-1thgA:
37.2		 1w76B-1thgA:
31.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 8 TYR A 333
ALA A 224
HIS A 225
LEU A 253
 None
 1.16A 1x8vA-1thgA:
undetectable		 1x8vA-1thgA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 ALA A 382
SER A 386
PHE A 379
ASP A 539
 None
 0.99A 1yc2A-1thgA:
undetectable		 1yc2A-1thgA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 5 TYR A 481
SER A 449
THR A 461
ASN A 465
 None
 1.25A 1yvpA-1thgA:
undetectable		 1yvpA-1thgA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 TYR A 481
SER A 449
THR A 461
ASN A 465
 None
 1.14A 1yvpB-1thgA:
undetectable		 1yvpB-1thgA:
23.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 7 GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.61A 2ackA-1thgA:
37.5		 2ackA-1thgA:
31.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 7 GLY A 131
SER A 217
PHE A 358
HIS A 463
 None
 1.09A 2ackA-1thgA:
37.5		 2ackA-1thgA:
31.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 ILE A 228
ALA A 229
LEU A 187
ILE A 128
PHE A 336
 None
 1.16A 2h77A-1thgA:
undetectable		 2h77A-1thgA:
18.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 8 TYR A 141
GLU A 216
PHE A 358
HIS A 463
GLY A 464
 None
 0.53A 2ha4A-1thgA:
36.4		 2ha4A-1thgA:
30.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 7 TYR A 141
GLU A 216
HIS A 463
GLY A 464
 None
 0.44A 2ha4B-1thgA:
36.5		 2ha4B-1thgA:
30.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 PHE A 358
ASN A 350
LEU A 448
ALA A 420
SER A 402
 None
 1.33A 2iyfB-1thgA:
2.5		 2iyfB-1thgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 ALA A 218
GLY A 170
PRO A 321
GLY A 320
LEU A 106
 None
 1.05A 2plwA-1thgA:
undetectable		 2plwA-1thgA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 5 LEU A 313
PRO A 314
LEU A 317
ILE A 378
 None
 0.86A 2qd4A-1thgA:
3.1		 2qd4A-1thgA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 8 ILE A 327
PHE A 336
GLY A 231
GLY A 232
 None
 0.81A 2qx4A-1thgA:
2.6
2qx4B-1thgA:
undetectable		 2qx4A-1thgA:
19.60
2qx4B-1thgA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 10 TYR A 135
ALA A 140
ALA A 139
SER A 138
TYR A 129
 None
 1.43A 2r2vC-1thgA:
undetectable
2r2vF-1thgA:
undetectable
2r2vG-1thgA:
undetectable		 2r2vC-1thgA:
6.21
2r2vF-1thgA:
6.21
2r2vG-1thgA:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 8 PHE A 319
ALA A 300
LEU A 297
PHE A  39
 None
 0.85A 2vcvP-1thgA:
undetectable		 2vcvP-1thgA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 476
ILE A 516
LEU A 452
LEU A 455
VAL A 456
 None
 0.90A 2yqzB-1thgA:
3.0		 2yqzB-1thgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 THR A 356
PHE A 462
LEU A  77
LEU A  73
 None
 1.18A 3bgdA-1thgA:
undetectable		 3bgdA-1thgA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		3 / 3 GLY A 215
GLY A 130
GLY A 219
 None
 0.43A 3bogC-1thgA:
undetectable		 3bogC-1thgA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 11 GLN A 470
SER A 222
TRP A 127
GLY A 215
GLY A 219
 None
 1.15A 3gy3A-1thgA:
undetectable		 3gy3A-1thgA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 GLU A 466
ASN A 465
SER A 217
PHE A 428
 None
 1.40A 3i9jB-1thgA:
undetectable		 3i9jB-1thgA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1thg LIPASE 2
(Galactomyces
candidus) 		3 / 3 ASN A 499
ASN A 479
GLU A 149
 None
 0.82A 3kpdB-1thgA:
undetectable		 3kpdB-1thgA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 LEU A  91
ALA A 218
GLY A 355
ALA A 357
LEU A 459
 None
 1.08A 3ln1D-1thgA:
1.2		 3ln1D-1thgA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 5 TYR A 146
GLN A 470
LEU A 467
PHE A 471
 None
 1.23A 3ls4L-1thgA:
undetectable		 3ls4L-1thgA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		6 / 10 LEU A 297
ALA A 271
ASN A 268
ILE A 265
GLY A 174
ILE A 177
 None
 1.44A 3lzvA-1thgA:
undetectable		 3lzvA-1thgA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 7 GLY A 131
GLY A 130
SER A 217
PHE A 428
HIS A 463
 None
 1.49A 3o9mA-1thgA:
36.8		 3o9mA-1thgA:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 LEU A 297
LEU A 172
ARG A  38
PRO A 168
GLY A 173
 None
 1.29A 3okxB-1thgA:
undetectable		 3okxB-1thgA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 PHE A 358
LEU A 467
VAL A 134
ALA A 218
HIS A 463
 None
 1.45A 3u9fD-1thgA:
0.0
3u9fE-1thgA:
0.0		 3u9fD-1thgA:
17.57
3u9fE-1thgA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 PHE A 358
LEU A 467
VAL A 134
ALA A 218
HIS A 463
 None
 1.46A 3u9fG-1thgA:
0.0
3u9fH-1thgA:
0.0		 3u9fG-1thgA:
17.57
3u9fH-1thgA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 4 PRO A 321
LEU A 187
ILE A 327
ARG A 191
 None
 1.36A 3w1wA-1thgA:
3.4		 3w1wA-1thgA:
21.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BDS_A_THAA701_1
(CHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 9 GLU A 216
SER A 217
ALA A 357
HIS A 463
GLY A 464
 None
 0.39A 4bdsA-1thgA:
37.2		 4bdsA-1thgA:
30.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 PHE A 204
ALA A   5
PRO A  28
LEU A   7
 None
 0.91A 4dubB-1thgA:
undetectable		 4dubB-1thgA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 PHE A 242
TYR A 447
GLY A 219
ALA A 220
LEU A 227
 None
 0.93A 4e1gA-1thgA:
0.0		 4e1gA-1thgA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 PHE A 242
TYR A 447
GLY A 219
ALA A 220
LEU A 227
 None
 0.92A 4e1gB-1thgA:
undetectable		 4e1gB-1thgA:
21.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 130
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.49A 4ey6B-1thgA:
37.0		 4ey6B-1thgA:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 130
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.93A 4ey6B-1thgA:
37.0		 4ey6B-1thgA:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 GLY A 131
GLU A 216
SER A 217
PHE A 358
HIS A 463
 None
 0.87A 4ey6B-1thgA:
37.0		 4ey6B-1thgA:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 11 GLY A 130
GLU A 216
SER A 217
HIS A 463
GLY A 464
 None
 1.27A 4ey7A-1thgA:
37.0		 4ey7A-1thgA:
31.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 11 GLY A 130
GLU A 216
SER A 217
HIS A 463
GLY A 464
 None
 1.27A 4ey7B-1thgA:
36.8		 4ey7B-1thgA:
31.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 4 LEU A 313
PRO A 314
LEU A 317
ILE A 378
 None
 0.92A 4f4dB-1thgA:
3.1		 4f4dB-1thgA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 ALA A 382
ASN A 541
LEU A 542
VAL A 540
 None
 1.08A 4g24A-1thgA:
undetectable		 4g24A-1thgA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 7 PRO A 252
VAL A 434
MET A 435
ALA A 438
 None
 0.63A 4lb2A-1thgA:
1.9		 4lb2A-1thgA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 11 PHE A 358
ASN A 350
LEU A 448
ALA A 420
SER A 402
 None
 1.35A 4m83A-1thgA:
undetectable		 4m83A-1thgA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 1thg LIPASE 2
(Galactomyces
candidus) 		3 / 3 SER A 217
MET A 221
ASP A 425
 None
 0.84A 4mm4B-1thgA:
0.0		 4mm4B-1thgA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		3 / 3 SER A 487
ASP A 493
GLN A 502
 None
 0.93A 4oltA-1thgA:
undetectable
4oltB-1thgA:
undetectable		 4oltA-1thgA:
19.56
4oltB-1thgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		3 / 3 GLN A 502
SER A 487
ASP A 493
 None
 0.91A 4qwpA-1thgA:
undetectable
4qwpB-1thgA:
undetectable		 4qwpA-1thgA:
19.56
4qwpB-1thgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 ALA A 245
SER A 244
VAL A 344
VAL A 157
HIS A 492
 None
 1.50A 4zj8A-1thgA:
0.8		 4zj8A-1thgA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 7 VAL A 126
ILE A 213
PHE A 242
VAL A 211
ILE A 201
 None
 1.43A 5bmvC-1thgA:
2.4		 5bmvC-1thgA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 5 PRO A  90
HIS A 451
TYR A 146
PHE A 485
 None
 1.46A 5igjA-1thgA:
undetectable		 5igjA-1thgA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 8 TYR A 273
THR A 278
PRO A 263
ILE A 265
 None
 1.08A 5jhdE-1thgA:
undetectable
5jhdG-1thgA:
undetectable		 5jhdE-1thgA:
18.63
5jhdG-1thgA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 LEU A  91
ALA A 218
GLY A 355
ALA A 357
LEU A 459
 None
 1.07A 5jw1B-1thgA:
0.0		 5jw1B-1thgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 LEU A  91
ASP A  65
GLY A  67
LEU A  73
ALA A 357
 None
 1.39A 5kc4E-1thgA:
undetectable		 5kc4E-1thgA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 6 TYR A 164
PRO A 168
LEU A 172
PHE A 171
 None
 1.12A 5tl8A-1thgA:
undetectable		 5tl8A-1thgA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1thg LIPASE 2
(Galactomyces
candidus) 		4 / 9 VAL A 371
HIS A 370
LEU A 393
ASP A 388
 None
NAG  A 990 (-3.4A)
None
None
 0.84A 6c2mD-1thgA:
undetectable		 6c2mD-1thgA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 1thg LIPASE 2
(Galactomyces
candidus) 		5 / 12 LEU A 335
PRO A 329
HIS A 188
THR A 178
GLY A 181
 None
 1.31A 6mn8A-1thgA:
undetectable		 6mn8A-1thgA:
21.42