SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1thx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 1thx THIOREDOXIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A   3
ILE A  42
ASN A  43
VAL A  25
LEU A  53
 None
 1.28A 3ay0B-1thxA:
undetectable		 3ay0B-1thxA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1thx THIOREDOXIN
(Nostoc
sp.
PCC
7120) 		4 / 7 PHE A 102
LEU A  80
LEU A  53
LEU A  24
 None
 0.68A 3bgdB-1thxA:
undetectable		 3bgdB-1thxA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 1thx THIOREDOXIN
(Nostoc
sp.
PCC
7120) 		5 / 12 MET A  38
LEU A  41
LEU A  44
ALA A  45
LEU A  78
 None
 0.81A 4pxmA-1thxA:
undetectable		 4pxmA-1thxA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1thx THIOREDOXIN
(Nostoc
sp.
PCC
7120) 		4 / 8 LEU A  99
LEU A 100
GLY A   3
TYR A  49
 None
 0.90A 6ce2A-1thxA:
undetectable		 6ce2A-1thxA:
23.53