SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tis'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AXW_B_MTXB733_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 11	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.16A	1axwB-1tisA: 32.1	1axwB-1tisA: 45.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1B02_A_C2FA281_0 (PROTEIN (THYMIDYLATE SYNTHASE))	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 11	ALA A 51 LEU A 153 ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	1.27A	1b02A-1tisA: 28.1	1b02A-1tisA: 35.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_A_DVAA8_0 (GRAMICIDIN A)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	3 / 4	VAL A 140 TRP A 173 TRP A 113	None	1.19A	1gmkA-1tisA: undetectable 1gmkB-1tisA: undetectable	1gmkA-1tisA: 7.47 1gmkB-1tisA: 7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_C_DVAC8_0 (GRAMICIDIN A)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	3 / 4	VAL A 140 TRP A 173 TRP A 113	None	1.02A	1gmkC-1tisA: undetectable 1gmkD-1tisA: undetectable	1gmkC-1tisA: 7.47 1gmkD-1tisA: 7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_A_DVAA6_0 (GRAMICIDIN A)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	3 / 3	ALA A 189 VAL A 45 TRP A 36	None	0.95A	1grmA-1tisA: undetectable	1grmA-1tisA: 7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_B_DVAB6_0 (GRAMICIDIN A)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	3 / 3	ALA A 189 VAL A 45 TRP A 36	None	0.95A	1grmB-1tisA: undetectable	1grmB-1tisA: 7.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_A_D16A414_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.08A	1hvyA-1tisA: 30.6	1hvyA-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_A_D16A414_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 12	GLU A 58 ASN A 90 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	1.09A	1hvyA-1tisA: 30.6	1hvyA-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_B_D16B415_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.13A	1hvyB-1tisA: 30.6	1hvyB-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_C_D16C416_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 11	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.03A	1hvyC-1tisA: 30.7	1hvyC-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_C_D16C416_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 11	GLU A 58 ASN A 90 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.96A	1hvyC-1tisA: 30.7	1hvyC-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.94A	1hvyD-1tisA: 30.6	1hvyD-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	GLU A 58 ASN A 90 GLY A 183 PHE A 186 TYR A 219	None	1.07A	1hvyD-1tisA: 30.6	1hvyD-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1HVY_D_D16D417_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	GLU A 58 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.83A	1hvyD-1tisA: 30.6	1hvyD-1tisA: 43.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I00_A_D16A315_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	GLU A 58 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.70A	1i00A-1tisA: 29.8	1i00A-1tisA: 43.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I00_A_D16A315_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	GLU A 58 TRP A 87 ASP A 179 PHE A 186 TYR A 219	None	0.60A	1i00A-1tisA: 29.8	1i00A-1tisA: 43.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I00_B_D16B409_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	ASP A 179 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.69A	1i00B-1tisA: 29.9	1i00B-1tisA: 43.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_D_VDYD1001_5 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	3 / 3	THR A 254 LEU A 258 VAL A 261	None	0.49A	1mz9E-1tisA: undetectable	1mz9E-1tisA: 10.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_A_D16A309_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.60A	1rtsA-1tisA: 30.5	1rtsA-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_A_D16A309_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.59A	1rtsA-1tisA: 30.5	1rtsA-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_B_D16B409_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.48A	1rtsB-1tisA: 30.8	1rtsB-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RTS_B_D16B409_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.52A	1rtsB-1tisA: 30.8	1rtsB-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2KCE_B_D16B568_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.00A	2kceB-1tisA: 31.7	2kceB-1tisA: 45.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_A_D16A309_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.46A	2tsrA-1tisA: 30.8	2tsrA-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_A_D16A309_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.46A	2tsrA-1tisA: 30.8	2tsrA-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_B_D16B409_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 8	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.97A	2tsrB-1tisA: 30.6	2tsrB-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_C_D16C509_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 10	GLU A 58 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.63A	2tsrC-1tisA: 30.7	2tsrC-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_D_D16D609_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.90A	2tsrD-1tisA: 30.7	2tsrD-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2TSR_D_D16D609_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	ASP A 179 LEU A 182 GLY A 183 TYR A 219 THR A 47	None	1.29A	2tsrD-1tisA: 30.7	2tsrD-1tisA: 41.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XFH_A_CL6A1414_1 (ERYTHROMYCIN B/D C-12 HYDROXYLASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 8	MET A 201 LEU A 59 ILE A 60 LEU A 63 LEU A 194	None	1.33A	2xfhA-1tisA: undetectable	2xfhA-1tisA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_A_LYAA513_1 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ALA A 51 ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.92A	3k2hA-1tisA: 29.8	3k2hA-1tisA: 25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_B_LYAB513_1 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ALA A 51 ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.88A	3k2hB-1tisA: 30.2	3k2hB-1tisA: 25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPC_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 11	ILE A 197 THR A 193 TRP A 52 VAL A 261 ILE A 60	None	0.87A	3kpcA-1tisA: undetectable	3kpcA-1tisA: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NRR_A_D16A530_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ALA A 51 ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	1.09A	3nrrA-1tisA: 9.3	3nrrA-1tisA: 25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NRR_B_D16B530_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ALA A 51 ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	1.13A	3nrrB-1tisA: 9.2	3nrrB-1tisA: 25.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UWL_B_FOZB316_0 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	HIS A 157 LEU A 182 GLY A 183 ASN A 187 TYR A 219	None	0.72A	3uwlB-1tisA: 30.4	3uwlB-1tisA: 41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3UWL_D_FOZD316_0 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	HIS A 157 LEU A 182 GLY A 183 ASN A 187 TYR A 219	None	0.73A	3uwlD-1tisA: 29.7	3uwlD-1tisA: 41.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BBO_B_ACTB1114_0 (BLR5658 PROTEIN)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	3 / 3	TRP A 87 TRP A 61 THR A 67	None	1.49A	4bboB-1tisA: undetectable	4bboB-1tisA: 17.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.74A	4eb4A-1tisA: 30.1	4eb4A-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.02A	4eb4A-1tisA: 30.1	4eb4A-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.75A	4eb4B-1tisA: 30.2	4eb4B-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.04A	4eb4B-1tisA: 30.2	4eb4B-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_C_D16C402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	ASP A 179 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.71A	4eb4C-1tisA: 30.2	4eb4C-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 10	ASP A 179 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.69A	4eb4D-1tisA: 30.2	4eb4D-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EB4_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 10	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.93A	4eb4D-1tisA: 30.2	4eb4D-1tisA: 41.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FOG_D_C2FD302_0 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 11	LEU A 153 ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.93A	4fogD-1tisA: 31.1	4fogD-1tisA: 46.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.52A	4iqqA-1tisA: 30.4	4iqqA-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.57A	4iqqA-1tisA: 30.4	4iqqA-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.55A	4iqqB-1tisA: 29.9	4iqqB-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.57A	4iqqB-1tisA: 29.9	4iqqB-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_C_D16C402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.48A	4iqqC-1tisA: 30.1	4iqqC-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_C_D16C402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.37A	4iqqC-1tisA: 30.1	4iqqC-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IQQ_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 8	LYS A 48 ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	1.32A	4iqqD-1tisA: 30.3	4iqqD-1tisA: 39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZDZ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ILE A 210 GLY A 213 THR A 216 LEU A 184	None	0.83A	4zdzA-1tisA: undetectable	4zdzA-1tisA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CP3_A_YTZA301_1 (LIGHT CHAIN OF ANTIGEN-BINDING FRAGMENT OF MONOCLONAL ANTIBODY OF 4C7 HEAVY CHAIN OF ANTIGEN-BINDING FRAGMENT OF MONOCLONAL ANTIBODY OF 4C7)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 11	HIS A 217 ASN A 215 ALA A 28 TYR A 219 GLY A 25	None	1.37A	5cp3A-1tisA: undetectable 5cp3H-1tisA: undetectable	5cp3A-1tisA: 22.51 5cp3H-1tisA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESE_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ILE A 210 GLY A 213 THR A 216 LEU A 184	None	0.87A	5eseA-1tisA: undetectable	5eseA-1tisA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESF_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ILE A 210 GLY A 213 THR A 216 LEU A 184	None	0.82A	5esfA-1tisA: 1.1	5esfA-1tisA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESH_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ALA A 54 ILE A 210 GLY A 213 THR A 216 LEU A 184	None	1.08A	5eshA-1tisA: undetectable	5eshA-1tisA: 17.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H3A_A_D16A401_1 (ORF70)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.45A	5h3aA-1tisA: 30.3	5h3aA-1tisA: 40.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H3A_B_D16B401_1 (ORF70)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.49A	5h3aB-1tisA: 30.5	5h3aB-1tisA: 40.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5H3A_B_D16B401_1 (ORF70)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.48A	5h3aB-1tisA: 30.5	5h3aB-1tisA: 40.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0T_A_SAMA501_1 (PEPTIDE N-METHYLTRANSFERASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 5	TYR A 160 SER A 141 ALA A 142 GLN A 175	None	1.21A	5n0tA-1tisA: undetectable	5n0tA-1tisA: 20.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.53A	5nooA-1tisA: 30.2	5nooA-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_A_D16A402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.60A	5nooA-1tisA: 30.2	5nooA-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.57A	5nooB-1tisA: 30.2	5nooB-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.57A	5nooB-1tisA: 30.2	5nooB-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_C_D16C402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 6	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.95A	5nooC-1tisA: 29.8	5nooC-1tisA: 39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5NOO_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 8	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.92A	5nooD-1tisA: 30.2	5nooD-1tisA: 39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM2_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 9	VAL A 261 LEU A 63 ASP A 120 VAL A 198 ILE A 197	None	0.89A	5om2A-1tisA: undetectable 5om2B-1tisA: undetectable	5om2A-1tisA: 13.19 5om2B-1tisA: 9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_C_CVIC301_1 (REGULATORY PROTEIN TETR)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	GLN A 175 GLY A 183 ILE A 188 GLN A 5	None	1.11A	5vlmC-1tisA: 0.0	5vlmC-1tisA: 20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.95A	5x5qB-1tisA: 31.0	5x5qB-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_B_D16B402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	GLU A 58 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.69A	5x5qB-1tisA: 31.0	5x5qB-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.55A	5x5qC-1tisA: 30.7	5x5qC-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_C_D16C402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 7	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.54A	5x5qC-1tisA: 30.7	5x5qC-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.54A	5x5qD-1tisA: 30.7	5x5qD-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_D_D16D402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 8	LYS A 48 ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	1.12A	5x5qD-1tisA: 30.7	5x5qD-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_E_D16E402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 6	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.54A	5x5qE-1tisA: 30.7	5x5qE-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_F_D16F402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ASP A 179 GLY A 183 PHE A 186 TYR A 219	None	0.53A	5x5qF-1tisA: 30.6	5x5qF-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X5Q_F_D16F402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	4 / 8	ASP A 179 LEU A 182 GLY A 183 TYR A 219	None	0.53A	5x5qF-1tisA: 30.6	5x5qF-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_A_MTXA402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.80A	5x66A-1tisA: 31.0 5x66B-1tisA: 31.0	5x66A-1tisA: 43.41 5x66B-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_C_MTXC402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 9	ASP A 179 LEU A 182 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.87A	5x66C-1tisA: 31.1	5x66C-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_D_MTXD402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 10	ASP A 179 GLY A 183 PHE A 186 ASN A 187 TYR A 219	None	0.68A	5x66D-1tisA: 31.1	5x66D-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5X66_F_MTXF402_1 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASP A 179 LEU A 182 GLY A 183 PHE A 186 TYR A 219	None	0.73A	5x66F-1tisA: 31.1	5x66F-1tisA: 43.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 12	ASN A 90 TYR A 109 LEU A 153 GLY A 183 ASN A 187 ALA A 285	None	1.50A	6r2eE-1tisA: 30.3	6r2eE-1tisA: 38.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_E_FFOE403_0 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	6 / 12	TRP A 87 ASN A 90 TYR A 109 LEU A 153 ASN A 187 ALA A 285	None	1.31A	6r2eE-1tisA: 30.3	6r2eE-1tisA: 38.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6R2E_H_FFOH403_0 (THYMIDYLATE SYNTHASE)	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	5 / 12	ASN A 90 TYR A 109 LEU A 153 ASN A 187 ALA A 285	None	1.26A	6r2eH-1tisA: 30.5	6r2eH-1tisA: 38.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AXW_B_MTXB733_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.16A","1axwB-1tisA:32.1","1axwB-1tisA:45.73"],["1B02_A_C2FA281_0","PROTEIN (THYMIDYLATE SYNTHASE)","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",6,"ALA A  51;LEU A 153;ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","1.27A","1b02A-1tisA:28.1","1b02A-1tisA:35.53"],["1GMK_A_DVAA8_0","GRAMICIDIN A","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",3,"VAL A 140;TRP A 173;TRP A 113","None","1.19A","1gmkA-1tisA:undetectable;1gmkB-1tisA:undetectable","1gmkA-1tisA:7.47;1gmkB-1tisA:7.47"],["1GMK_C_DVAC8_0","GRAMICIDIN A","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",3,"VAL A 140;TRP A 173;TRP A 113","None","1.02A","1gmkC-1tisA:undetectable;1gmkD-1tisA:undetectable","1gmkC-1tisA:7.47;1gmkD-1tisA:7.47"],["1GRM_A_DVAA6_0","GRAMICIDIN A","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",3,"ALA A 189;VAL A  45;TRP A  36","None","0.95A","1grmA-1tisA:undetectable","1grmA-1tisA:7.47"],["1GRM_B_DVAB6_0","GRAMICIDIN A","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",3,"ALA A 189;VAL A  45;TRP A  36","None","0.95A","1grmB-1tisA:undetectable","1grmB-1tisA:7.47"],["1HVY_A_D16A414_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.08A","1hvyA-1tisA:30.6","1hvyA-1tisA:43.23"],["1HVY_A_D16A414_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",6,"GLU A  58;ASN A  90;ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","1.09A","1hvyA-1tisA:30.6","1hvyA-1tisA:43.23"],["1HVY_B_D16B415_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.13A","1hvyB-1tisA:30.6","1hvyB-1tisA:43.23"],["1HVY_C_D16C416_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.03A","1hvyC-1tisA:30.7","1hvyC-1tisA:43.23"],["1HVY_C_D16C416_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",6,"GLU A  58;ASN A  90;ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.96A","1hvyC-1tisA:30.7","1hvyC-1tisA:43.23"],["1HVY_D_D16D417_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","0.94A","1hvyD-1tisA:30.6","1hvyD-1tisA:43.23"],["1HVY_D_D16D417_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"GLU A  58;ASN A  90;GLY A 183;PHE A 186;TYR A 219","None","1.07A","1hvyD-1tisA:30.6","1hvyD-1tisA:43.23"],["1HVY_D_D16D417_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"GLU A  58;ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.83A","1hvyD-1tisA:30.6","1hvyD-1tisA:43.23"],["1I00_A_D16A315_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"GLU A  58;ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.70A","1i00A-1tisA:29.8","1i00A-1tisA:43.27"],["1I00_A_D16A315_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"GLU A  58;TRP A  87;ASP A 179;PHE A 186;TYR A 219","None","0.60A","1i00A-1tisA:29.8","1i00A-1tisA:43.27"],["1I00_B_D16B409_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;GLY A 183;PHE A 186;ASN A 187;TYR A 219","None","0.69A","1i00B-1tisA:29.9","1i00B-1tisA:43.27"],["1MZ9_D_VDYD1001_5","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",3,"THR A 254;LEU A 258;VAL A 261","None","0.49A","1mz9E-1tisA:undetectable","1mz9E-1tisA:10.14"],["1RTS_A_D16A309_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.60A","1rtsA-1tisA:30.5","1rtsA-1tisA:41.10"],["1RTS_A_D16A309_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.59A","1rtsA-1tisA:30.5","1rtsA-1tisA:41.10"],["1RTS_B_D16B409_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.48A","1rtsB-1tisA:30.8","1rtsB-1tisA:41.10"],["1RTS_B_D16B409_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.52A","1rtsB-1tisA:30.8","1rtsB-1tisA:41.10"],["2KCE_B_D16B568_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.00A","2kceB-1tisA:31.7","2kceB-1tisA:45.73"],["2TSR_A_D16A309_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.46A","2tsrA-1tisA:30.8","2tsrA-1tisA:41.10"],["2TSR_A_D16A309_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.46A","2tsrA-1tisA:30.8","2tsrA-1tisA:41.10"],["2TSR_B_D16B409_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","0.97A","2tsrB-1tisA:30.6","2tsrB-1tisA:41.10"],["2TSR_C_D16C509_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"GLU A  58;ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.63A","2tsrC-1tisA:30.7","2tsrC-1tisA:41.10"],["2TSR_D_D16D609_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","0.90A","2tsrD-1tisA:30.7","2tsrD-1tisA:41.10"],["2TSR_D_D16D609_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;TYR A 219;THR A  47","None","1.29A","2tsrD-1tisA:30.7","2tsrD-1tisA:41.10"],["2XFH_A_CL6A1414_1","ERYTHROMYCIN B\/D C-12 HYDROXYLASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"MET A 201;LEU A  59;ILE A  60;LEU A  63;LEU A 194","None","1.33A","2xfhA-1tisA:undetectable","2xfhA-1tisA:21.35"],["3K2H_A_LYAA513_1","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ALA A  51;ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.92A","3k2hA-1tisA:29.8","3k2hA-1tisA:25.29"],["3K2H_B_LYAB513_1","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ALA A  51;ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.88A","3k2hB-1tisA:30.2","3k2hB-1tisA:25.29"],["3KPC_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ILE A 197;THR A 193;TRP A  52;VAL A 261;ILE A  60","None","0.87A","3kpcA-1tisA:undetectable","3kpcA-1tisA:17.96"],["3NRR_A_D16A530_1","DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ALA A  51;ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","1.09A","3nrrA-1tisA:9.3","3nrrA-1tisA:25.29"],["3NRR_B_D16B530_1","DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ALA A  51;ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","1.13A","3nrrB-1tisA:9.2","3nrrB-1tisA:25.29"],["3UWL_B_FOZB316_0","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"HIS A 157;LEU A 182;GLY A 183;ASN A 187;TYR A 219","None","0.72A","3uwlB-1tisA:30.4","3uwlB-1tisA:41.90"],["3UWL_D_FOZD316_0","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"HIS A 157;LEU A 182;GLY A 183;ASN A 187;TYR A 219","None","0.73A","3uwlD-1tisA:29.7","3uwlD-1tisA:41.90"],["4BBO_B_ACTB1114_0","BLR5658 PROTEIN","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",3,"TRP A  87;TRP A  61;THR A  67","None","1.49A","4bboB-1tisA:undetectable","4bboB-1tisA:17.71"],["4EB4_A_D16A402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;GLY A 183;PHE A 186;ASN A 187;TYR A 219","None","0.74A","4eb4A-1tisA:30.1","4eb4A-1tisA:41.10"],["4EB4_A_D16A402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.02A","4eb4A-1tisA:30.1","4eb4A-1tisA:41.10"],["4EB4_B_D16B402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;GLY A 183;PHE A 186;ASN A 187;TYR A 219","None","0.75A","4eb4B-1tisA:30.2","4eb4B-1tisA:41.10"],["4EB4_B_D16B402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 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183;TYR A 219","None","0.37A","4iqqC-1tisA:30.1","4iqqC-1tisA:39.29"],["4IQQ_D_D16D402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",6,"LYS A  48;ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","1.32A","4iqqD-1tisA:30.3","4iqqD-1tisA:39.29"],["4ZDZ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ILE A 210;GLY A 213;THR A 216;LEU A 184","None","0.83A","4zdzA-1tisA:undetectable","4zdzA-1tisA:17.39"],["5CP3_A_YTZA301_1","LIGHT CHAIN OF ANTIGEN-BINDING FRAGMENT OF MONOCLONAL ANTIBODY OF 4C7;HEAVY CHAIN OF ANTIGEN-BINDING FRAGMENT OF MONOCLONAL ANTIBODY OF 4C7","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"HIS A 217;ASN A 215;ALA A  28;TYR A 219;GLY A  25","None","1.37A","5cp3A-1tisA:undetectable;5cp3H-1tisA:undetectable","5cp3A-1tisA:22.51;5cp3H-1tisA:22.76"],["5ESE_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ILE A 210;GLY A 213;THR A 216;LEU A 184","None","0.87A","5eseA-1tisA:undetectable","5eseA-1tisA:17.39"],["5ESF_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ILE A 210;GLY A 213;THR A 216;LEU A 184","None","0.82A","5esfA-1tisA:1.1","5esfA-1tisA:17.39"],["5ESH_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ALA A  54;ILE A 210;GLY A 213;THR A 216;LEU A 184","None","1.08A","5eshA-1tisA:undetectable","5eshA-1tisA:17.39"],["5H3A_A_D16A401_1","ORF70","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.45A","5h3aA-1tisA:30.3","5h3aA-1tisA:40.79"],["5H3A_B_D16B401_1","ORF70","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.49A","5h3aB-1tisA:30.5","5h3aB-1tisA:40.79"],["5H3A_B_D16B401_1","ORF70","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.48A","5h3aB-1tisA:30.5","5h3aB-1tisA:40.79"],["5N0T_A_SAMA501_1","PEPTIDE N-METHYLTRANSFERASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"TYR A 160;SER A 141;ALA A 142;GLN A 175","None","1.21A","5n0tA-1tisA:undetectable","5n0tA-1tisA:20.75"],["5NOO_A_D16A402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.53A","5nooA-1tisA:30.2","5nooA-1tisA:39.29"],["5NOO_A_D16A402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.60A","5nooA-1tisA:30.2","5nooA-1tisA:39.29"],["5NOO_B_D16B402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;GLY A 183;PHE A 186;TYR A 219","None","0.57A","5nooB-1tisA:30.2","5nooB-1tisA:39.29"],["5NOO_B_D16B402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"ASP A 179;LEU A 182;GLY A 183;TYR A 219","None","0.57A","5nooB-1tisA:30.2","5nooB-1tisA:39.29"],["5NOO_C_D16C402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","0.95A","5nooC-1tisA:29.8","5nooC-1tisA:39.29"],["5NOO_D_D16D402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","0.92A","5nooD-1tisA:30.2","5nooD-1tisA:39.29"],["5OM2_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"VAL A 261;LEU A  63;ASP A 120;VAL A 198;ILE A 197","None","0.89A","5om2A-1tisA:undetectable;5om2B-1tisA:undetectable","5om2A-1tisA:13.19;5om2B-1tisA:9.23"],["5VLM_C_CVIC301_1","REGULATORY PROTEIN TETR","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",4,"GLN A 175;GLY A 183;ILE A 188;GLN A   5","None","1.11A","5vlmC-1tisA:0.0","5vlmC-1tisA:20.96"],["5X5Q_B_D16B402_1","THYMIDYLATE 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219","None","0.80A","5x66A-1tisA:31.0;5x66B-1tisA:31.0","5x66A-1tisA:43.41;5x66B-1tisA:43.41"],["5X66_C_MTXC402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",6,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;ASN A 187;TYR A 219","None","0.87A","5x66C-1tisA:31.1","5x66C-1tisA:43.41"],["5X66_D_MTXD402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;GLY A 183;PHE A 186;ASN A 187;TYR A 219","None","0.68A","5x66D-1tisA:31.1","5x66D-1tisA:43.41"],["5X66_F_MTXF402_1","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",5,"ASP A 179;LEU A 182;GLY A 183;PHE A 186;TYR A 219","None","0.73A","5x66F-1tisA:31.1","5x66F-1tisA:43.41"],["6R2E_E_FFOE403_0","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE SYNTHASE","Escherichia virus T4",6,"ASN A  90;TYR A 109;LEU A 153;GLY A 183;ASN A 187;ALA A 285","None","1.50A","6r2eE-1tisA:30.3","6r2eE-1tisA:38.90"],["6R2E_E_FFOE403_0","THYMIDYLATE SYNTHASE","1tis","THYMIDYLATE 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