SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 8 SER A  86
VAL A  88
ALA A  81
TRP A  87
 None
 1.08A 1dmiA-1tj7A:
1.0
1dmiB-1tj7A:
0.0		 1dmiA-1tj7A:
21.98
1dmiB-1tj7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		3 / 3 MET A 246
LEU A 249
SER A 250
 None
 0.56A 1ee2A-1tj7A:
undetectable		 1ee2A-1tj7A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 6 MET A 341
LEU A 128
ALA A 131
LEU A 129
 None
 1.16A 1etb1-1tj7A:
undetectable		 1etb1-1tj7A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		3 / 3 THR A 124
LEU A 128
LEU A 135
 None
 0.58A 1mz9C-1tj7A:
undetectable		 1mz9C-1tj7A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 8 THR A 105
LEU A  44
VAL A  47
GLY A  48
 None
 0.84A 2a1oA-1tj7A:
undetectable		 2a1oA-1tj7A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		3 / 3 ARG A 109
GLU A 323
SER A 108
 PO4  A 601 (-3.7A)
None
PO4  A 601 (-3.1A)
 0.93A 2xkkA-1tj7A:
undetectable
2xkkC-1tj7A:
undetectable		 2xkkA-1tj7A:
23.17
2xkkC-1tj7A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 5 ALA A 242
GLY A 297
CYH A 296
LYS A 295
 None
 1.30A 2yldA-1tj7A:
2.9		 2yldA-1tj7A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 5 ALA A 242
GLY A 297
CYH A 296
LYS A 295
 None
 1.44A 2ylgA-1tj7A:
2.9		 2ylgA-1tj7A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.41A 2zj0A-1tj7A:
undetectable		 2zj0A-1tj7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.39A 3ce6A-1tj7A:
undetectable		 3ce6A-1tj7A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.38A 3ce6C-1tj7A:
undetectable		 3ce6C-1tj7A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		6 / 12 LEU A 103
GLY A 100
GLY A  97
ASP A  94
LEU A  58
LEU A  62
 None
 1.32A 3cjtO-1tj7A:
undetectable		 3cjtO-1tj7A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.42A 3glqA-1tj7A:
undetectable		 3glqA-1tj7A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		3 / 3 ARG A 109
ASP A 116
ASP A  83
 PO4  A 601 (-3.7A)
None
None
 0.81A 3jayA-1tj7A:
undetectable		 3jayA-1tj7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 3n58D-1tj7A:
undetectable		 3n58D-1tj7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 5 ALA A 242
GLY A 297
CYH A 296
LYS A 295
 None
 1.26A 3zwiA-1tj7A:
3.0		 3zwiA-1tj7A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.37A 4lvcA-1tj7A:
undetectable		 4lvcA-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.40A 4lvcC-1tj7A:
undetectable		 4lvcC-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 11 LEU A  62
SER A  41
VAL A  96
LEU A  99
LEU A 103
 None
 1.12A 4or0B-1tj7A:
1.6		 4or0B-1tj7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 11 LEU A  62
VAL A  96
LEU A  99
LEU A  65
LEU A 103
 None
 1.22A 4or0B-1tj7A:
1.6		 4or0B-1tj7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		3 / 3 PRO A 194
LEU A 195
HIS A 104
 None
 0.61A 4pevA-1tj7A:
undetectable		 4pevA-1tj7A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.39A 4pfjA-1tj7A:
undetectable		 4pfjA-1tj7A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 4 ILE A 257
ASN A 260
ILE A 349
VAL A 345
 None
 1.27A 4uy87-1tj7A:
undetectable		 4uy87-1tj7A:
5.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 9 LEU A 425
GLU A 403
THR A 368
VAL A 388
VAL A 392
 None
 1.41A 4wnvB-1tj7A:
0.0		 4wnvB-1tj7A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 10 ASP A 337
LEU A 336
LEU A 135
ALA A 131
LEU A 346
 None
 1.16A 4zbrA-1tj7A:
undetectable		 4zbrA-1tj7A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.41A 5axaA-1tj7A:
undetectable		 5axaA-1tj7A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.40A 5axaC-1tj7A:
undetectable		 5axaC-1tj7A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 9 THR A 142
GLN A 184
ASN A 132
LEU A 135
LEU A 346
 None
 1.11A 5fhzB-1tj7A:
undetectable		 5fhzB-1tj7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 10 THR A 142
GLN A 184
ASN A 132
LEU A 135
LEU A 346
 None
 1.10A 5fhzC-1tj7A:
1.6		 5fhzC-1tj7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8A-1tj7A:
undetectable		 5hm8A-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8B-1tj7A:
undetectable		 5hm8B-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8C-1tj7A:
undetectable		 5hm8C-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8D-1tj7A:
undetectable		 5hm8D-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8E-1tj7A:
undetectable		 5hm8E-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8F-1tj7A:
undetectable		 5hm8F-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8G-1tj7A:
undetectable		 5hm8G-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.47A 5hm8H-1tj7A:
undetectable		 5hm8H-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 4 CYH A 121
LEU A 238
LEU A 190
ALA A 186
 None
 0.78A 5hpuA-1tj7A:
undetectable
5hpuB-1tj7A:
undetectable		 5hpuA-1tj7A:
4.70
5hpuB-1tj7A:
5.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 5 ALA A 242
GLY A 297
CYH A 296
LYS A 295
 None
 1.35A 5jliA-1tj7A:
3.0		 5jliA-1tj7A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		4 / 5 ALA A 242
GLY A 297
CYH A 296
LYS A 295
 None
 1.29A 5jt4A-1tj7A:
3.0		 5jt4A-1tj7A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.42A 5m5kA-1tj7A:
undetectable		 5m5kA-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.42A 5m5kC-1tj7A:
undetectable		 5m5kC-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.38A 5m66A-1tj7A:
undetectable		 5m66A-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.41A 5m66B-1tj7A:
undetectable		 5m66B-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.46A 5utuH-1tj7A:
undetectable		 5utuH-1tj7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.40A 5v96A-1tj7A:
undetectable		 5v96A-1tj7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.40A 5v96B-1tj7A:
undetectable		 5v96B-1tj7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.39A 5v96C-1tj7A:
undetectable		 5v96C-1tj7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.39A 5v96D-1tj7A:
undetectable		 5v96D-1tj7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 9 VAL A  49
LEU A  50
GLY A 100
LEU A  99
GLN A  98
 None
 1.28A 6czmA-1tj7A:
undetectable
6czmB-1tj7A:
undetectable		 6czmA-1tj7A:
24.48
6czmB-1tj7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.43A 6exiC-1tj7A:
undetectable		 6exiC-1tj7A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.42A 6gbnA-1tj7A:
undetectable		 6gbnA-1tj7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.41A 6gbnC-1tj7A:
undetectable		 6gbnC-1tj7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 1tj7 ARGININOSUCCINATE
LYASE
(Escherichia
coli) 		5 / 12 LEU A 103
HIS A 104
ASP A  33
LEU A   3
HIS A  85
 None
 1.43A 6gbnD-1tj7A:
undetectable		 6gbnD-1tj7A:
23.96