SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		3 / 3 LYS A 101
ASP A 137
ASP A 133
 None
 0.91A 2br4D-1tjlA:
undetectable		 2br4D-1tjlA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		4 / 6 PHE A  82
HIS A  61
THR A  58
VAL A  59
 None
 1.24A 3lb3B-1tjlA:
1.8		 3lb3B-1tjlA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 112
VAL A 119
ALA A 132
LEU A  37
LEU A 126
 None
 0.94A 3mteA-1tjlA:
undetectable		 3mteA-1tjlA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 112
VAL A 119
ALA A 132
LEU A  37
LEU A 126
 None
 0.93A 3mteB-1tjlA:
undetectable		 3mteB-1tjlA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 112
VAL A 119
ALA A 132
LEU A  37
LEU A 126
 None
 0.96A 3p2kB-1tjlA:
undetectable		 3p2kB-1tjlA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 112
VAL A 119
ALA A 132
LEU A  37
LEU A 126
 None
 0.93A 3p2kC-1tjlA:
undetectable		 3p2kC-1tjlA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1tjl DNAK SUPPRESSOR
PROTEIN
(Escherichia
coli) 		5 / 12 GLY A 112
VAL A 119
ALA A 132
LEU A  37
LEU A 126
 None
 1.01A 3p2kD-1tjlA:
undetectable		 3p2kD-1tjlA:
23.30