SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A  31
VAL A  90
TRP A 115
 None
 0.94A 1c4dA-1tjyA:
undetectable
1c4dB-1tjyA:
undetectable		 1c4dA-1tjyA:
5.63
1c4dB-1tjyA:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 TRP A 115
ALA A  31
VAL A  90
 None
 0.86A 1c4dA-1tjyA:
undetectable
1c4dB-1tjyA:
undetectable		 1c4dA-1tjyA:
5.63
1c4dB-1tjyA:
5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A  94
VAL A  70
ASN A  78
LYS A 103
 None
 1.09A 1hwiB-1tjyA:
undetectable		 1hwiB-1tjyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A  94
VAL A  70
ASN A  78
LYS A 103
 None
 1.13A 1hwkA-1tjyA:
undetectable		 1hwkA-1tjyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A  94
VAL A  70
ASN A  78
LYS A 103
 None
 1.09A 1hwkC-1tjyA:
undetectable		 1hwkC-1tjyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A  94
VAL A  70
ASN A  78
LYS A 103
 None
 1.08A 1hwkD-1tjyA:
undetectable		 1hwkD-1tjyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 GLU A 262
HIS A 146
ASP A 333
 None
 0.85A 1i9gA-1tjyA:
5.4		 1i9gA-1tjyA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 MET A 139
ASN A 129
GLN A 271
 None
 0.88A 1xoqB-1tjyA:
undetectable		 1xoqB-1tjyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ASP A 118
ILE A 128
GLY A 320
ASN A 319
ILE A 321
 None
 1.04A 2e7fA-1tjyA:
2.2		 2e7fA-1tjyA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A  31
ASN A 280
VAL A  90
LEU A 113
ASP A  86
 None
 1.04A 2f8lA-1tjyA:
3.8		 2f8lA-1tjyA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O7O_A_DXTA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 SER A 305
PRO A 325
THR A 303
VAL A 302
ILE A 128
 None
 1.28A 2o7oA-1tjyA:
0.1		 2o7oA-1tjyA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 VAL A 278
TYR A 126
VAL A 304
ASP A 292
 None
 1.33A 2x45A-1tjyA:
undetectable		 2x45A-1tjyA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 VAL A 278
TYR A 126
VAL A 304
ASP A 292
 None
 1.29A 2x45C-1tjyA:
0.0		 2x45C-1tjyA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 SER A 305
PRO A 325
THR A 303
VAL A 302
ILE A 128
 None
 1.23A 2xpvA-1tjyA:
0.2		 2xpvA-1tjyA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 ASP A 118
ILE A 128
GLY A 320
ASN A 319
ILE A 321
 None
 0.98A 2ycjA-1tjyA:
2.7		 2ycjA-1tjyA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 4 SER A 161
GLY A  97
GLU A 122
 None
 0.50A 3raeA-1tjyA:
undetectable
3raeC-1tjyA:
3.5		 3raeA-1tjyA:
21.04
3raeC-1tjyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 225
ALA A 227
PHE A 158
ASN A 195
 None
 1.47A 3uq6A-1tjyA:
4.7		 3uq6A-1tjyA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 4 LEU A 225
ALA A 227
PHE A 158
ASN A 195
 None
 1.50A 3vasA-1tjyA:
4.6		 3vasA-1tjyA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 6 THR A 303
ARG A 327
ILE A 128
LEU A 294
 None
 1.03A 4acbC-1tjyA:
4.6		 4acbC-1tjyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 THR A 198
ASP A 196
TYR A 194
PHE A 192
 None
 0.93A 4drjB-1tjyA:
undetectable		 4drjB-1tjyA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 GLY A 320
VAL A 304
PRO A 306
ASN A 307
 None
 0.42A 4forA-1tjyA:
2.4		 4forA-1tjyA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 ILE A 207
ALA A 156
VAL A 155
ALA A 228
 None
 0.76A 4g77A-1tjyA:
2.4		 4g77A-1tjyA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 4 SER A 161
GLY A  97
GLU A 122
 None
 0.55A 4juoA-1tjyA:
undetectable
4juoC-1tjyA:
3.2		 4juoA-1tjyA:
21.04
4juoC-1tjyA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 7 ASN A 238
LYS A 236
TYR A 254
PHE A 263
 None
 1.23A 4yv5B-1tjyA:
undetectable		 4yv5B-1tjyA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		3 / 3 ILE A 296
PRO A 297
ILE A 299
 None
 0.40A 5hw8F-1tjyA:
undetectable		 5hw8F-1tjyA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 ILE A 242
ALA A 228
ILE A 207
ILE A 208
 None
 0.72A 5mvmA-1tjyA:
undetectable
5mvmB-1tjyA:
undetectable		 5mvmA-1tjyA:
13.36
5mvmB-1tjyA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 GLU A 142
GLY A 137
GLN A 135
LEU A 136
 None
 0.94A 5sxtA-1tjyA:
undetectable		 5sxtA-1tjyA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		4 / 8 GLU A 142
GLY A 137
GLN A 135
LEU A 136
 None
 0.94A 5sxtB-1tjyA:
undetectable		 5sxtB-1tjyA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1tjy SUGAR TRANSPORT
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 137
PHE A  32
ILE A  89
GLY A 272
LEU A 324
 None
 1.23A 6e8qA-1tjyA:
undetectable		 6e8qA-1tjyA:
14.24