SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 1k2rA-1tkiA:
undetectable
1k2rB-1tkiA:
undetectable		 1k2rA-1tkiA:
20.37
1k2rB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 1k2sA-1tkiA:
undetectable
1k2sB-1tkiA:
undetectable		 1k2sA-1tkiA:
20.37
1k2sB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 1k2sA-1tkiA:
0.0
1k2sB-1tkiA:
0.0		 1k2sA-1tkiA:
20.37
1k2sB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 1k2uA-1tkiA:
undetectable
1k2uB-1tkiA:
undetectable		 1k2uA-1tkiA:
20.37
1k2uB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 1k2uA-1tkiA:
0.0
1k2uB-1tkiA:
0.0		 1k2uA-1tkiA:
20.37
1k2uB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 1lzxA-1tkiA:
undetectable
1lzxB-1tkiA:
undetectable		 1lzxA-1tkiA:
20.37
1lzxB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 1lzzA-1tkiA:
undetectable
1lzzB-1tkiA:
undetectable		 1lzzA-1tkiA:
20.37
1lzzB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 1mmvA-1tkiA:
undetectable
1mmvB-1tkiA:
undetectable		 1mmvA-1tkiA:
20.37
1mmvB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 1mmvA-1tkiA:
undetectable
1mmvB-1tkiA:
undetectable		 1mmvA-1tkiA:
20.37
1mmvB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 1mmwA-1tkiA:
undetectable
1mmwB-1tkiA:
undetectable		 1mmwA-1tkiA:
20.37
1mmwB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 1mmwA-1tkiA:
undetectable
1mmwB-1tkiA:
undetectable		 1mmwA-1tkiA:
20.37
1mmwB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 1om4A-1tkiA:
undetectable
1om4B-1tkiA:
undetectable		 1om4A-1tkiA:
20.23
1om4B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.45A 1om5A-1tkiA:
undetectable
1om5B-1tkiA:
undetectable		 1om5A-1tkiA:
20.28
1om5B-1tkiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 1p6hA-1tkiA:
undetectable
1p6hB-1tkiA:
undetectable		 1p6hA-1tkiA:
20.28
1p6hB-1tkiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 1p6iA-1tkiA:
undetectable
1p6iB-1tkiA:
undetectable		 1p6iA-1tkiA:
20.28
1p6iB-1tkiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 1p6jA-1tkiA:
undetectable
1p6jB-1tkiA:
undetectable		 1p6jA-1tkiA:
20.28
1p6jB-1tkiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1tki TITIN
(Homo
sapiens) 		4 / 8 ALA A 269
ASP A 144
ILE A 145
ILE A 150
 None
 0.85A 1rg9B-1tkiA:
undetectable		 1rg9B-1tkiA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1tki TITIN
(Homo
sapiens) 		4 / 6 ARG A 323
ASP A 202
ASN A 139
GLU A 164
 None
 1.33A 1rjdC-1tkiA:
undetectable		 1rjdC-1tkiA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 8 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 1rs6A-1tkiA:
undetectable
1rs6B-1tkiA:
undetectable		 1rs6A-1tkiA:
20.28
1rs6B-1tkiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 ASP A  61
VAL A  65
GLY A  36
ILE A  37
 None
 0.75A 1t7iB-1tkiA:
undetectable		 1t7iB-1tkiA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 ASP A  61
VAL A  65
GLY A  36
ILE A  37
 None
 0.77A 1t7jB-1tkiA:
undetectable		 1t7jB-1tkiA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1tki TITIN
(Homo
sapiens) 		3 / 3 LEU A  72
PHE A 165
ARG A  78
 None
 0.87A 1xdkB-1tkiA:
undetectable		 1xdkB-1tkiA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1tki TITIN
(Homo
sapiens) 		4 / 6 ALA A 168
PHE A 165
ILE A 145
ASP A 202
 None
 0.97A 1yc2A-1tkiA:
undetectable		 1yc2A-1tkiA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1tki TITIN
(Homo
sapiens) 		4 / 5 ALA A 168
PHE A 165
ILE A 145
ASP A 202
 None
 1.02A 1yc2D-1tkiA:
undetectable		 1yc2D-1tkiA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.46A 1zvlA-1tkiA:
undetectable
1zvlB-1tkiA:
0.8		 1zvlA-1tkiA:
20.90
1zvlB-1tkiA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 1zzqA-1tkiA:
undetectable
1zzqB-1tkiA:
undetectable		 1zzqA-1tkiA:
20.46
1zzqB-1tkiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 1zzqA-1tkiA:
undetectable
1zzqB-1tkiA:
undetectable		 1zzqA-1tkiA:
20.46
1zzqB-1tkiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 1tki TITIN
(Homo
sapiens) 		5 / 12 ILE A 150
LEU A 209
THR A 208
LEU A 206
SER A 205
 None
 1.05A 2bdmA-1tkiA:
undetectable		 2bdmA-1tkiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1tki TITIN
(Homo
sapiens) 		5 / 11 GLY A 141
TYR A 187
ARG A 146
VAL A 191
GLU A 164
 None
 1.19A 2fl5A-1tkiA:
undetectable
2fl5B-1tkiA:
undetectable
2fl5F-1tkiA:
undetectable		 2fl5A-1tkiA:
20.12
2fl5B-1tkiA:
20.64
2fl5F-1tkiA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 2hx4A-1tkiA:
undetectable
2hx4B-1tkiA:
undetectable		 2hx4A-1tkiA:
20.23
2hx4B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TYR A 186
VAL A 210
TYR A 298
ILE A 105
 None
 1.30A 2xz5B-1tkiA:
undetectable
2xz5E-1tkiA:
undetectable		 2xz5B-1tkiA:
20.90
2xz5E-1tkiA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3b3mA-1tkiA:
undetectable
3b3mB-1tkiA:
undetectable		 3b3mA-1tkiA:
20.23
3b3mB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3b3mA-1tkiA:
undetectable
3b3mB-1tkiA:
undetectable		 3b3mA-1tkiA:
20.23
3b3mB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 3b3nA-1tkiA:
undetectable
3b3nB-1tkiA:
undetectable		 3b3nA-1tkiA:
20.23
3b3nB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 8 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 3b3pA-1tkiA:
undetectable
3b3pB-1tkiA:
undetectable		 3b3pA-1tkiA:
20.23
3b3pB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 1tki TITIN
(Homo
sapiens) 		3 / 3 GLU A 164
SER A 317
VAL A  38
 None
 0.83A 3eeoA-1tkiA:
undetectable		 3eeoA-1tkiA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3fc5A-1tkiA:
undetectable
3fc5B-1tkiA:
undetectable		 3fc5A-1tkiA:
20.46
3fc5B-1tkiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3fc5A-1tkiA:
undetectable
3fc5B-1tkiA:
undetectable		 3fc5A-1tkiA:
20.46
3fc5B-1tkiA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3hsoA-1tkiA:
undetectable
3hsoB-1tkiA:
undetectable		 3hsoA-1tkiA:
20.23
3hsoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 3hspA-1tkiA:
undetectable
3hspB-1tkiA:
undetectable		 3hspA-1tkiA:
20.23
3hspB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1tki TITIN
(Homo
sapiens) 		5 / 12 ASN A  79
GLU A 130
VAL A 285
ILE A 282
GLU A 283
 None
 1.46A 3jayA-1tkiA:
1.0		 3jayA-1tkiA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3jt3A-1tkiA:
undetectable
3jt3B-1tkiA:
undetectable		 3jt3A-1tkiA:
20.23
3jt3B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 3jt3A-1tkiA:
undetectable
3jt3B-1tkiA:
undetectable		 3jt3A-1tkiA:
20.23
3jt3B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3jt6A-1tkiA:
undetectable
3jt6B-1tkiA:
undetectable		 3jt6A-1tkiA:
20.23
3jt6B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 3jtaA-1tkiA:
undetectable
3jtaB-1tkiA:
undetectable		 3jtaA-1tkiA:
20.23
3jtaB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3jwsA-1tkiA:
undetectable
3jwsB-1tkiA:
undetectable		 3jwsA-1tkiA:
20.23
3jwsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3jwsA-1tkiA:
undetectable
3jwsB-1tkiA:
undetectable		 3jwsA-1tkiA:
20.23
3jwsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 3jwtA-1tkiA:
undetectable
3jwtB-1tkiA:
undetectable		 3jwtA-1tkiA:
20.23
3jwtB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 3jwuA-1tkiA:
undetectable
3jwuB-1tkiA:
undetectable		 3jwuA-1tkiA:
20.23
3jwuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3jwuA-1tkiA:
undetectable
3jwuB-1tkiA:
undetectable		 3jwuA-1tkiA:
20.23
3jwuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 3jwvA-1tkiA:
undetectable
3jwvB-1tkiA:
undetectable		 3jwvA-1tkiA:
20.23
3jwvB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 3jx0A-1tkiA:
undetectable
3jx0B-1tkiA:
undetectable		 3jx0A-1tkiA:
20.37
3jx0B-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3jx1A-1tkiA:
undetectable
3jx1B-1tkiA:
undetectable		 3jx1A-1tkiA:
20.37
3jx1B-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3n5yA-1tkiA:
undetectable
3n5yB-1tkiA:
undetectable		 3n5yA-1tkiA:
20.23
3n5yB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3n5yA-1tkiA:
undetectable
3n5yB-1tkiA:
undetectable		 3n5yA-1tkiA:
20.23
3n5yB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 3n5zA-1tkiA:
undetectable
3n5zB-1tkiA:
undetectable		 3n5zA-1tkiA:
20.23
3n5zB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 3n5zA-1tkiA:
undetectable
3n5zB-1tkiA:
undetectable		 3n5zA-1tkiA:
20.23
3n5zB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3nlnA-1tkiA:
undetectable
3nlnB-1tkiA:
undetectable		 3nlnA-1tkiA:
20.23
3nlnB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3nloA-1tkiA:
undetectable
3nloB-1tkiA:
undetectable		 3nloA-1tkiA:
20.23
3nloB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 3nlwA-1tkiA:
undetectable
3nlwB-1tkiA:
undetectable		 3nlwA-1tkiA:
20.23
3nlwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3nlxA-1tkiA:
undetectable
3nlxB-1tkiA:
undetectable		 3nlxA-1tkiA:
20.23
3nlxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.46A 3nlyA-1tkiA:
undetectable
3nlyB-1tkiA:
undetectable		 3nlyA-1tkiA:
20.23
3nlyB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3nnyA-1tkiA:
undetectable
3nnyB-1tkiA:
undetectable		 3nnyA-1tkiA:
20.23
3nnyB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3nnzA-1tkiA:
undetectable
3nnzB-1tkiA:
undetectable		 3nnzA-1tkiA:
20.23
3nnzB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 1tki TITIN
(Homo
sapiens) 		4 / 8 ASP A  61
VAL A  65
GLY A  36
ILE A  37
 None
 0.76A 3nu9A-1tkiA:
undetectable		 3nu9A-1tkiA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TYR A  50
ILE A  96
SER A  45
SER A  46
 None
 0.93A 3pmzD-1tkiA:
undetectable		 3pmzD-1tkiA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3pnfA-1tkiA:
undetectable
3pnfB-1tkiA:
undetectable		 3pnfA-1tkiA:
20.23
3pnfB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3pngA-1tkiA:
undetectable
3pngB-1tkiA:
undetectable		 3pngA-1tkiA:
20.23
3pngB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3rqjA-1tkiA:
undetectable
3rqjB-1tkiA:
0.0		 3rqjA-1tkiA:
20.23
3rqjB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3rqmA-1tkiA:
undetectable
3rqmB-1tkiA:
undetectable		 3rqmA-1tkiA:
20.23
3rqmB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3rqmA-1tkiA:
undetectable
3rqmB-1tkiA:
undetectable		 3rqmA-1tkiA:
20.23
3rqmB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3rqnA-1tkiA:
undetectable
3rqnB-1tkiA:
undetectable		 3rqnA-1tkiA:
20.23
3rqnB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3tymA-1tkiA:
undetectable
3tymB-1tkiA:
undetectable		 3tymA-1tkiA:
20.23
3tymB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3tynA-1tkiA:
undetectable
3tynB-1tkiA:
undetectable		 3tynA-1tkiA:
20.23
3tynB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3tyoA-1tkiA:
undetectable
3tyoB-1tkiA:
undetectable		 3tyoA-1tkiA:
20.23
3tyoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1tki TITIN
(Homo
sapiens) 		5 / 12 SER A 205
LEU A 171
PHE A 177
VAL A 197
HIS A 136
 None
 1.41A 3u9fD-1tkiA:
0.0
3u9fE-1tkiA:
0.0		 3u9fD-1tkiA:
19.81
3u9fE-1tkiA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3ufpA-1tkiA:
undetectable
3ufpB-1tkiA:
undetectable		 3ufpA-1tkiA:
20.23
3ufpB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 3ufqA-1tkiA:
undetectable
3ufqB-1tkiA:
undetectable		 3ufqA-1tkiA:
20.23
3ufqB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 3ufsA-1tkiA:
undetectable
3ufsB-1tkiA:
undetectable		 3ufsA-1tkiA:
20.23
3ufsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 3ufsA-1tkiA:
undetectable
3ufsB-1tkiA:
undetectable		 3ufsA-1tkiA:
20.23
3ufsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 3ufuA-1tkiA:
undetectable
3ufuB-1tkiA:
undetectable		 3ufuA-1tkiA:
20.23
3ufuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 3ufwA-1tkiA:
undetectable
3ufwB-1tkiA:
undetectable		 3ufwA-1tkiA:
20.23
3ufwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4c39A-1tkiA:
undetectable
4c39B-1tkiA:
undetectable		 4c39A-1tkiA:
20.23
4c39B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4c39A-1tkiA:
undetectable
4c39B-1tkiA:
undetectable		 4c39A-1tkiA:
20.23
4c39B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4camA-1tkiA:
undetectable
4camB-1tkiA:
undetectable		 4camA-1tkiA:
20.23
4camB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4camA-1tkiA:
undetectable
4camB-1tkiA:
undetectable		 4camA-1tkiA:
20.23
4camB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 4canA-1tkiA:
undetectable
4canB-1tkiA:
undetectable		 4canA-1tkiA:
20.23
4canB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 4canA-1tkiA:
undetectable
4canB-1tkiA:
undetectable		 4canA-1tkiA:
20.23
4canB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4caoA-1tkiA:
undetectable
4caoB-1tkiA:
undetectable		 4caoA-1tkiA:
20.23
4caoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4caqA-1tkiA:
undetectable
4caqB-1tkiA:
undetectable		 4caqA-1tkiA:
20.23
4caqB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4ctpA-1tkiA:
undetectable
4ctpB-1tkiA:
undetectable		 4ctpA-1tkiA:
20.23
4ctpB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 4ctqA-1tkiA:
undetectable
4ctqB-1tkiA:
undetectable		 4ctqA-1tkiA:
20.23
4ctqB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.45A 4ctrA-1tkiA:
undetectable
4ctrB-1tkiA:
undetectable		 4ctrA-1tkiA:
20.23
4ctrB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4ctrA-1tkiA:
undetectable
4ctrB-1tkiA:
undetectable		 4ctrA-1tkiA:
20.23
4ctrB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.45A 4cttA-1tkiA:
undetectable
4cttB-1tkiA:
undetectable		 4cttA-1tkiA:
20.23
4cttB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 4cttA-1tkiA:
undetectable
4cttB-1tkiA:
undetectable		 4cttA-1tkiA:
20.23
4cttB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4ctuA-1tkiA:
undetectable
4ctuB-1tkiA:
undetectable		 4ctuA-1tkiA:
20.23
4ctuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4ctuA-1tkiA:
undetectable
4ctuB-1tkiA:
undetectable		 4ctuA-1tkiA:
20.23
4ctuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 4ctvA-1tkiA:
undetectable
4ctvB-1tkiA:
undetectable		 4ctvA-1tkiA:
20.23
4ctvB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4ctvA-1tkiA:
undetectable
4ctvB-1tkiA:
undetectable		 4ctvA-1tkiA:
20.23
4ctvB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4ctwA-1tkiA:
undetectable
4ctwB-1tkiA:
undetectable		 4ctwA-1tkiA:
20.23
4ctwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4ctwA-1tkiA:
undetectable
4ctwB-1tkiA:
undetectable		 4ctwA-1tkiA:
20.23
4ctwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4ctxA-1tkiA:
undetectable
4ctxB-1tkiA:
undetectable		 4ctxA-1tkiA:
20.23
4ctxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4ctxA-1tkiA:
undetectable
4ctxB-1tkiA:
undetectable		 4ctxA-1tkiA:
20.23
4ctxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4cx5A-1tkiA:
undetectable
4cx5B-1tkiA:
undetectable		 4cx5A-1tkiA:
20.23
4cx5B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 4cx5A-1tkiA:
undetectable
4cx5B-1tkiA:
undetectable		 4cx5A-1tkiA:
20.23
4cx5B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4cx6A-1tkiA:
undetectable
4cx6B-1tkiA:
undetectable		 4cx6A-1tkiA:
20.23
4cx6B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4cx6A-1tkiA:
undetectable
4cx6B-1tkiA:
undetectable		 4cx6A-1tkiA:
20.23
4cx6B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4d2yA-1tkiA:
undetectable
4d2yB-1tkiA:
undetectable		 4d2yA-1tkiA:
20.23
4d2yB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4d2zA-1tkiA:
undetectable
4d2zB-1tkiA:
undetectable		 4d2zA-1tkiA:
20.23
4d2zB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4d30A-1tkiA:
undetectable
4d30B-1tkiA:
undetectable		 4d30A-1tkiA:
20.23
4d30B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 4d31A-1tkiA:
undetectable
4d31B-1tkiA:
undetectable		 4d31A-1tkiA:
20.23
4d31B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 4d32A-1tkiA:
undetectable
4d32B-1tkiA:
undetectable		 4d32A-1tkiA:
20.23
4d32B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4d3bA-1tkiA:
undetectable
4d3bB-1tkiA:
undetectable		 4d3bA-1tkiA:
20.23
4d3bB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4d7oA-1tkiA:
undetectable
4d7oB-1tkiA:
undetectable		 4d7oA-1tkiA:
20.23
4d7oB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4euxA-1tkiA:
undetectable
4euxB-1tkiA:
undetectable		 4euxA-1tkiA:
20.23
4euxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 1tki TITIN
(Homo
sapiens) 		3 / 3 PHE A 114
TYR A 124
TYR A 152
 None
 0.75A 4ffwA-1tkiA:
3.1		 4ffwA-1tkiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 4fvwA-1tkiA:
undetectable
4fvwB-1tkiA:
undetectable		 4fvwA-1tkiA:
20.23
4fvwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4fvxA-1tkiA:
undetectable
4fvxB-1tkiA:
undetectable		 4fvxA-1tkiA:
20.23
4fvxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4fvxA-1tkiA:
undetectable
4fvxB-1tkiA:
undetectable		 4fvxA-1tkiA:
20.23
4fvxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 4fvzA-1tkiA:
undetectable
4fvzB-1tkiA:
undetectable		 4fvzA-1tkiA:
20.23
4fvzB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 4fw0A-1tkiA:
undetectable
4fw0B-1tkiA:
undetectable		 4fw0A-1tkiA:
20.23
4fw0B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4imtA-1tkiA:
undetectable
4imtB-1tkiA:
undetectable		 4imtA-1tkiA:
20.23
4imtB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4imuA-1tkiA:
0.0
4imuB-1tkiA:
0.0		 4imuA-1tkiA:
20.23
4imuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4imuA-1tkiA:
0.0
4imuB-1tkiA:
0.0		 4imuA-1tkiA:
20.23
4imuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4jsgA-1tkiA:
undetectable
4jsgB-1tkiA:
undetectable		 4jsgA-1tkiA:
20.23
4jsgB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 4jsiA-1tkiA:
undetectable
4jsiB-1tkiA:
undetectable		 4jsiA-1tkiA:
20.23
4jsiB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 4jsiA-1tkiA:
undetectable
4jsiB-1tkiA:
undetectable		 4jsiA-1tkiA:
20.23
4jsiB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4jsjA-1tkiA:
undetectable
4jsjB-1tkiA:
undetectable		 4jsjA-1tkiA:
20.23
4jsjB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4k5dA-1tkiA:
undetectable
4k5dB-1tkiA:
undetectable		 4k5dA-1tkiA:
20.23
4k5dB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4k5fA-1tkiA:
undetectable
4k5fB-1tkiA:
undetectable		 4k5fA-1tkiA:
20.23
4k5fB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4k5fA-1tkiA:
undetectable
4k5fB-1tkiA:
undetectable		 4k5fA-1tkiA:
20.23
4k5fB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4k5gA-1tkiA:
undetectable
4k5gB-1tkiA:
undetectable		 4k5gA-1tkiA:
20.23
4k5gB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4kciA-1tkiA:
0.0
4kciB-1tkiA:
0.0		 4kciA-1tkiA:
20.23
4kciB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4kcmA-1tkiA:
undetectable
4kcmB-1tkiA:
undetectable		 4kcmA-1tkiA:
20.23
4kcmB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4kcmA-1tkiA:
undetectable
4kcmB-1tkiA:
undetectable		 4kcmA-1tkiA:
20.23
4kcmB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4kcoA-1tkiA:
undetectable
4kcoB-1tkiA:
undetectable		 4kcoA-1tkiA:
20.23
4kcoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1tki TITIN
(Homo
sapiens) 		4 / 8 ALA A 269
ASP A 144
ILE A 145
ILE A 150
 None
 0.81A 4kttB-1tkiA:
undetectable		 4kttB-1tkiA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1tki TITIN
(Homo
sapiens) 		4 / 8 ALA A 269
ASP A 144
ILE A 145
ILE A 150
 None
 0.82A 4kttD-1tkiA:
undetectable		 4kttD-1tkiA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 1tki TITIN
(Homo
sapiens) 		5 / 9 ASP A 144
VAL A 191
ALA A 188
TYR A 187
GLY A 141
 None
 1.30A 4mm5A-1tkiA:
undetectable		 4mm5A-1tkiA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 1tki TITIN
(Homo
sapiens) 		5 / 9 ASP A 144
VAL A 191
ALA A 188
TYR A 187
GLY A 141
 None
 1.31A 4mmbA-1tkiA:
undetectable		 4mmbA-1tkiA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 1tki TITIN
(Homo
sapiens) 		5 / 9 ASP A 144
VAL A 191
ALA A 188
TYR A 187
GLY A 141
 None
 1.25A 4mmeA-1tkiA:
undetectable		 4mmeA-1tkiA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1tki TITIN
(Homo
sapiens) 		5 / 9 ASP A 144
VAL A 191
ALA A 188
TYR A 187
GLY A 141
 None
 1.29A 4mmeB-1tkiA:
undetectable		 4mmeB-1tkiA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 1tki TITIN
(Homo
sapiens) 		5 / 9 ASP A 144
VAL A 191
ALA A 188
TYR A 187
GLY A 141
 None
 1.26A 4mmfA-1tkiA:
0.9		 4mmfA-1tkiA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 1tki TITIN
(Homo
sapiens) 		5 / 9 ASP A 144
VAL A 191
ALA A 188
TYR A 187
GLY A 141
 None
 1.30A 4mmfB-1tkiA:
undetectable		 4mmfB-1tkiA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 1tki TITIN
(Homo
sapiens) 		4 / 8 ILE A 150
ILE A 162
ASN A  79
ALA A 131
 None
 0.79A 4ou1A-1tkiA:
undetectable		 4ou1A-1tkiA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 4ugzA-1tkiA:
0.0
4ugzB-1tkiA:
0.0		 4ugzA-1tkiA:
20.23
4ugzB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 4ugzA-1tkiA:
undetectable
4ugzB-1tkiA:
undetectable		 4ugzA-1tkiA:
20.23
4ugzB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 4uh0A-1tkiA:
undetectable
4uh0B-1tkiA:
undetectable		 4uh0A-1tkiA:
20.23
4uh0B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4uh1A-1tkiA:
undetectable
4uh1B-1tkiA:
undetectable		 4uh1A-1tkiA:
20.23
4uh1B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 4uh2A-1tkiA:
undetectable
4uh2B-1tkiA:
undetectable		 4uh2A-1tkiA:
20.23
4uh2B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 4uh2A-1tkiA:
undetectable
4uh2B-1tkiA:
undetectable		 4uh2A-1tkiA:
20.23
4uh2B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4uh3A-1tkiA:
undetectable
4uh3B-1tkiA:
undetectable		 4uh3A-1tkiA:
20.23
4uh3B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4uh4A-1tkiA:
undetectable
4uh4B-1tkiA:
undetectable		 4uh4A-1tkiA:
20.23
4uh4B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4uh5A-1tkiA:
undetectable
4uh5B-1tkiA:
undetectable		 4uh5A-1tkiA:
20.51
4uh5B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 4uh6A-1tkiA:
undetectable
4uh6B-1tkiA:
undetectable		 4uh6A-1tkiA:
20.51
4uh6B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4upnA-1tkiA:
undetectable
4upnB-1tkiA:
undetectable		 4upnA-1tkiA:
20.23
4upnB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 4upoA-1tkiA:
undetectable
4upoB-1tkiA:
undetectable		 4upoA-1tkiA:
20.23
4upoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 4upoA-1tkiA:
undetectable
4upoB-1tkiA:
undetectable		 4upoA-1tkiA:
20.23
4upoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 4uppA-1tkiA:
undetectable
4uppB-1tkiA:
undetectable		 4uppA-1tkiA:
20.23
4uppB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4uppA-1tkiA:
undetectable
4uppB-1tkiA:
undetectable		 4uppA-1tkiA:
20.23
4uppB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 4v3vA-1tkiA:
undetectable
4v3vB-1tkiA:
undetectable		 4v3vA-1tkiA:
20.23
4v3vB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4v3wA-1tkiA:
0.0
4v3wB-1tkiA:
0.0		 4v3wA-1tkiA:
20.23
4v3wB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 4v3wA-1tkiA:
undetectable
4v3wB-1tkiA:
undetectable		 4v3wA-1tkiA:
20.23
4v3wB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 4v3xA-1tkiA:
undetectable
4v3xB-1tkiA:
undetectable		 4v3xA-1tkiA:
20.23
4v3xB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 4v3zA-1tkiA:
undetectable
4v3zB-1tkiA:
undetectable		 4v3zA-1tkiA:
20.23
4v3zB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 4v3zA-1tkiA:
undetectable
4v3zB-1tkiA:
undetectable		 4v3zA-1tkiA:
20.23
4v3zB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.46A 5ad4A-1tkiA:
undetectable
5ad4B-1tkiA:
undetectable		 5ad4A-1tkiA:
20.23
5ad4B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5ad5A-1tkiA:
undetectable
5ad5B-1tkiA:
undetectable		 5ad5A-1tkiA:
20.23
5ad5B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5ad5A-1tkiA:
0.0
5ad5B-1tkiA:
0.0		 5ad5A-1tkiA:
20.23
5ad5B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.46A 5ad6A-1tkiA:
undetectable
5ad6B-1tkiA:
undetectable		 5ad6A-1tkiA:
20.23
5ad6B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5ad7A-1tkiA:
0.0
5ad7B-1tkiA:
0.0		 5ad7A-1tkiA:
20.23
5ad7B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 5ad8A-1tkiA:
undetectable
5ad8B-1tkiA:
0.0		 5ad8A-1tkiA:
20.23
5ad8B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.46A 5ad9A-1tkiA:
undetectable
5ad9B-1tkiA:
undetectable		 5ad9A-1tkiA:
20.23
5ad9B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
HIS A 275
 None
 1.34A 5ad9A-1tkiA:
undetectable
5ad9B-1tkiA:
undetectable		 5ad9A-1tkiA:
20.23
5ad9B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5adaA-1tkiA:
undetectable
5adaB-1tkiA:
undetectable		 5adaA-1tkiA:
20.23
5adaB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5adbA-1tkiA:
0.0
5adbB-1tkiA:
0.0		 5adbA-1tkiA:
20.23
5adbB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5adcA-1tkiA:
undetectable
5adcB-1tkiA:
undetectable		 5adcA-1tkiA:
20.23
5adcB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 5adcA-1tkiA:
undetectable
5adcB-1tkiA:
undetectable		 5adcA-1tkiA:
20.23
5adcB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 5adfA-1tkiA:
undetectable
5adfB-1tkiA:
undetectable		 5adfA-1tkiA:
20.51
5adfB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5adgA-1tkiA:
undetectable
5adgB-1tkiA:
undetectable		 5adgA-1tkiA:
20.51
5adgB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 5adgA-1tkiA:
undetectable
5adgB-1tkiA:
undetectable		 5adgA-1tkiA:
20.51
5adgB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 5adiA-1tkiA:
undetectable
5adiB-1tkiA:
undetectable		 5adiA-1tkiA:
20.51
5adiB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5agkA-1tkiA:
undetectable
5agkB-1tkiA:
undetectable		 5agkA-1tkiA:
20.23
5agkB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5agkA-1tkiA:
undetectable
5agkB-1tkiA:
undetectable		 5agkA-1tkiA:
20.23
5agkB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 5aglA-1tkiA:
undetectable
5aglB-1tkiA:
undetectable		 5aglA-1tkiA:
20.23
5aglB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 5agmA-1tkiA:
undetectable
5agmB-1tkiA:
undetectable		 5agmA-1tkiA:
20.23
5agmB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5agnA-1tkiA:
undetectable
5agnB-1tkiA:
undetectable		 5agnA-1tkiA:
20.23
5agnB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5agoA-1tkiA:
undetectable
5agoB-1tkiA:
undetectable		 5agoA-1tkiA:
20.23
5agoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 5agoA-1tkiA:
undetectable
5agoB-1tkiA:
undetectable		 5agoA-1tkiA:
20.23
5agoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 5agpA-1tkiA:
undetectable
5agpB-1tkiA:
undetectable		 5agpA-1tkiA:
20.23
5agpB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.45A 5fvpA-1tkiA:
0.0
5fvpB-1tkiA:
0.0		 5fvpA-1tkiA:
20.23
5fvpB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5fvrA-1tkiA:
undetectable
5fvrB-1tkiA:
undetectable		 5fvrA-1tkiA:
20.23
5fvrB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 5fvrA-1tkiA:
undetectable
5fvrB-1tkiA:
undetectable		 5fvrA-1tkiA:
20.23
5fvrB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5fvsA-1tkiA:
undetectable
5fvsB-1tkiA:
undetectable		 5fvsA-1tkiA:
20.23
5fvsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5fvtA-1tkiA:
undetectable
5fvtB-1tkiA:
undetectable		 5fvtA-1tkiA:
20.23
5fvtB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 5fvtA-1tkiA:
undetectable
5fvtB-1tkiA:
undetectable		 5fvtA-1tkiA:
20.23
5fvtB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5fvuA-1tkiA:
undetectable
5fvuB-1tkiA:
0.9		 5fvuA-1tkiA:
20.51
5fvuB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5fw0A-1tkiA:
undetectable
5fw0B-1tkiA:
undetectable		 5fw0A-1tkiA:
20.23
5fw0B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 5g0nA-1tkiA:
undetectable
5g0nB-1tkiA:
undetectable		 5g0nA-1tkiA:
20.37
5g0nB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 5g0nA-1tkiA:
undetectable
5g0nB-1tkiA:
undetectable		 5g0nA-1tkiA:
20.37
5g0nB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5g0oA-1tkiA:
undetectable
5g0oB-1tkiA:
undetectable		 5g0oA-1tkiA:
20.37
5g0oB-1tkiA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 1tki TITIN
(Homo
sapiens) 		5 / 12 TYR A 152
PRO A 147
VAL A 128
LEU A 278
ILE A 290
 None
 1.21A 5hv1A-1tkiA:
undetectable		 5hv1A-1tkiA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 1tki TITIN
(Homo
sapiens) 		4 / 7 GLY A  31
GLY A  33
GLY A  36
VAL A  38
 None
 0.37A 5izjB-1tkiA:
25.4		 5izjB-1tkiA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 1tki TITIN
(Homo
sapiens) 		4 / 7 GLY A  31
GLY A  33
VAL A  38
LYS A  53
 None
 0.46A 5izjA-1tkiA:
19.6		 5izjA-1tkiA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J5X_B_AZ1B2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAL-DAR-DAR-
DAR-DAR)		 1tki TITIN
(Homo
sapiens) 		4 / 7 GLY A  31
GLY A  33
VAL A  38
LYS A  53
 None
 0.39A 5j5xA-1tkiA:
18.5		 5j5xA-1tkiA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 5unrA-1tkiA:
undetectable
5unrB-1tkiA:
undetectable		 5unrA-1tkiA:
20.23
5unrB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 5unsA-1tkiA:
0.0
5unsB-1tkiA:
0.0		 5unsA-1tkiA:
20.23
5unsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5unsA-1tkiA:
undetectable
5unsB-1tkiA:
undetectable		 5unsA-1tkiA:
20.23
5unsB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5untA-1tkiA:
undetectable
5untB-1tkiA:
0.0		 5untA-1tkiA:
20.23
5untB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5untA-1tkiA:
undetectable
5untB-1tkiA:
0.0		 5untA-1tkiA:
20.23
5untB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 5unuA-1tkiA:
undetectable
5unuB-1tkiA:
undetectable		 5unuA-1tkiA:
20.23
5unuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5unuA-1tkiA:
undetectable
5unuB-1tkiA:
undetectable		 5unuA-1tkiA:
20.23
5unuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.46A 5unwA-1tkiA:
undetectable
5unwB-1tkiA:
undetectable		 5unwA-1tkiA:
20.23
5unwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.45A 5unwA-1tkiA:
undetectable
5unwB-1tkiA:
undetectable		 5unwA-1tkiA:
20.23
5unwB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.44A 5unxA-1tkiA:
0.0
5unxB-1tkiA:
0.0		 5unxA-1tkiA:
20.23
5unxB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5unyA-1tkiA:
undetectable
5unyB-1tkiA:
undetectable		 5unyA-1tkiA:
20.23
5unyB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5unyA-1tkiA:
undetectable
5unyB-1tkiA:
undetectable		 5unyA-1tkiA:
20.23
5unyB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.44A 5unzA-1tkiA:
undetectable
5unzB-1tkiA:
undetectable		 5unzA-1tkiA:
20.23
5unzB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.43A 5uo0A-1tkiA:
undetectable
5uo0B-1tkiA:
undetectable		 5uo0A-1tkiA:
20.23
5uo0B-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5uo3A-1tkiA:
undetectable
5uo3B-1tkiA:
undetectable		 5uo3A-1tkiA:
20.51
5uo3B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5uo4A-1tkiA:
undetectable
5uo4B-1tkiA:
undetectable		 5uo4A-1tkiA:
20.51
5uo4B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5uo5A-1tkiA:
undetectable
5uo5B-1tkiA:
undetectable		 5uo5A-1tkiA:
20.51
5uo5B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.45A 5vuiA-1tkiA:
undetectable
5vuiB-1tkiA:
0.0		 5vuiA-1tkiA:
20.23
5vuiB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vuiA-1tkiA:
undetectable
5vuiB-1tkiA:
0.0		 5vuiA-1tkiA:
20.23
5vuiB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 5vujA-1tkiA:
undetectable
5vujB-1tkiA:
undetectable		 5vujA-1tkiA:
20.23
5vujB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.45A 5vujA-1tkiA:
undetectable
5vujB-1tkiA:
undetectable		 5vujA-1tkiA:
20.23
5vujB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.45A 5vukA-1tkiA:
undetectable
5vukB-1tkiA:
undetectable		 5vukA-1tkiA:
20.23
5vukB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vulA-1tkiA:
undetectable
5vulB-1tkiA:
undetectable		 5vulA-1tkiA:
20.23
5vulB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vumA-1tkiA:
undetectable
5vumB-1tkiA:
undetectable		 5vumA-1tkiA:
20.23
5vumB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vumA-1tkiA:
undetectable
5vumB-1tkiA:
undetectable		 5vumA-1tkiA:
20.23
5vumB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5vunA-1tkiA:
undetectable
5vunB-1tkiA:
undetectable		 5vunA-1tkiA:
20.23
5vunB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vuoA-1tkiA:
undetectable
5vuoB-1tkiA:
undetectable		 5vuoA-1tkiA:
20.23
5vuoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5vuoA-1tkiA:
undetectable
5vuoB-1tkiA:
undetectable		 5vuoA-1tkiA:
20.23
5vuoB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vupA-1tkiA:
undetectable
5vupB-1tkiA:
undetectable		 5vupA-1tkiA:
20.23
5vupB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vupA-1tkiA:
undetectable
5vupB-1tkiA:
undetectable		 5vupA-1tkiA:
20.23
5vupB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5vuqA-1tkiA:
undetectable
5vuqB-1tkiA:
undetectable		 5vuqA-1tkiA:
20.23
5vuqB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vuqA-1tkiA:
undetectable
5vuqB-1tkiA:
undetectable		 5vuqA-1tkiA:
20.23
5vuqB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.45A 5vurA-1tkiA:
undetectable
5vurB-1tkiA:
undetectable		 5vurA-1tkiA:
20.23
5vurB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 5vusA-1tkiA:
undetectable
5vusB-1tkiA:
undetectable		 5vusA-1tkiA:
20.23
5vusB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 5vusA-1tkiA:
undetectable
5vusB-1tkiA:
undetectable		 5vusA-1tkiA:
20.23
5vusB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vutA-1tkiA:
undetectable
5vutB-1tkiA:
undetectable		 5vutA-1tkiA:
20.23
5vutB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vuuA-1tkiA:
undetectable
5vuuB-1tkiA:
undetectable		 5vuuA-1tkiA:
20.23
5vuuB-1tkiA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 5vuvA-1tkiA:
undetectable
5vuvB-1tkiA:
undetectable		 5vuvA-1tkiA:
20.51
5vuvB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 5vuwA-1tkiA:
undetectable
5vuwB-1tkiA:
undetectable		 5vuwA-1tkiA:
20.51
5vuwB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 5vuxA-1tkiA:
undetectable
5vuxB-1tkiA:
undetectable		 5vuxA-1tkiA:
20.51
5vuxB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 5vuyA-1tkiA:
undetectable
5vuyB-1tkiA:
undetectable		 5vuyA-1tkiA:
20.51
5vuyB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.46A 5vuyA-1tkiA:
undetectable
5vuyB-1tkiA:
undetectable		 5vuyA-1tkiA:
20.51
5vuyB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vuzA-1tkiA:
undetectable
5vuzB-1tkiA:
undetectable		 5vuzA-1tkiA:
20.51
5vuzB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 5vuzA-1tkiA:
undetectable
5vuzB-1tkiA:
undetectable		 5vuzA-1tkiA:
20.51
5vuzB-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vv0A-1tkiA:
undetectable
5vv0B-1tkiA:
1.0		 5vv0A-1tkiA:
20.51
5vv0B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 5vv0A-1tkiA:
0.0
5vv0B-1tkiA:
0.0		 5vv0A-1tkiA:
20.51
5vv0B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vv1A-1tkiA:
undetectable
5vv1B-1tkiA:
undetectable		 5vv1A-1tkiA:
20.51
5vv1B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 5vv1A-1tkiA:
0.0
5vv1B-1tkiA:
0.0		 5vv1A-1tkiA:
20.51
5vv1B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 5vv2A-1tkiA:
undetectable
5vv2B-1tkiA:
undetectable		 5vv2A-1tkiA:
20.51
5vv2B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.50A 5vv2A-1tkiA:
undetectable
5vv2B-1tkiA:
undetectable		 5vv2A-1tkiA:
20.51
5vv2B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 5vv3A-1tkiA:
undetectable
5vv3B-1tkiA:
undetectable		 5vv3A-1tkiA:
20.51
5vv3B-1tkiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 6 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 6auqA-1tkiA:
undetectable
6auqB-1tkiA:
undetectable		 6auqA-1tkiA:
13.06
6auqB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 6auqA-1tkiA:
undetectable
6auqB-1tkiA:
undetectable		 6auqA-1tkiA:
13.06
6auqB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 6aurA-1tkiA:
undetectable
6aurB-1tkiA:
undetectable		 6aurA-1tkiA:
13.06
6aurB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 6aurA-1tkiA:
undetectable
6aurB-1tkiA:
undetectable		 6aurA-1tkiA:
13.06
6aurB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 6ausA-1tkiA:
undetectable
6ausB-1tkiA:
undetectable		 6ausA-1tkiA:
13.06
6ausB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 6autA-1tkiA:
undetectable
6autB-1tkiA:
undetectable		 6autA-1tkiA:
13.06
6autB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 6autA-1tkiA:
undetectable
6autB-1tkiA:
undetectable		 6autA-1tkiA:
13.06
6autB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.48A 6auuA-1tkiA:
undetectable
6auuB-1tkiA:
undetectable		 6auuA-1tkiA:
13.06
6auuB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 6auvA-1tkiA:
undetectable
6auvB-1tkiA:
undetectable		 6auvA-1tkiA:
13.06
6auvB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 6auwA-1tkiA:
undetectable
6auwB-1tkiA:
undetectable		 6auwA-1tkiA:
13.06
6auwB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 6auwA-1tkiA:
undetectable
6auwB-1tkiA:
undetectable		 6auwA-1tkiA:
13.06
6auwB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 6auxA-1tkiA:
undetectable
6auxB-1tkiA:
undetectable		 6auxA-1tkiA:
13.06
6auxB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.47A 6auxA-1tkiA:
undetectable
6auxB-1tkiA:
undetectable		 6auxA-1tkiA:
13.06
6auxB-1tkiA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 6auyA-1tkiA:
undetectable
6auyB-1tkiA:
undetectable		 6auyA-1tkiA:
13.38
6auyB-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 6auzA-1tkiA:
undetectable
6auzB-1tkiA:
undetectable		 6auzA-1tkiA:
13.38
6auzB-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 6av0A-1tkiA:
undetectable
6av0B-1tkiA:
undetectable		 6av0A-1tkiA:
13.38
6av0B-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.47A 6av1A-1tkiA:
undetectable
6av1B-1tkiA:
undetectable		 6av1A-1tkiA:
13.38
6av1B-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 6av2A-1tkiA:
undetectable
6av2B-1tkiA:
undetectable		 6av2A-1tkiA:
13.38
6av2B-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 6av3A-1tkiA:
undetectable
6av3B-1tkiA:
undetectable		 6av3A-1tkiA:
13.38
6av3B-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.48A 6av4A-1tkiA:
undetectable
6av4B-1tkiA:
undetectable		 6av4A-1tkiA:
13.38
6av4B-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1tki TITIN
(Homo
sapiens) 		3 / 3 HIS A  84
HIS A  82
ARG A  76
 None
 1.01A 6b58A-1tkiA:
undetectable		 6b58A-1tkiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.50A 6cicA-1tkiA:
undetectable
6cicB-1tkiA:
undetectable		 6cicA-1tkiA:
13.38
6cicB-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 VAL A 122
TRP A 277
PHE A 254
GLU A 250
 None
 1.49A 6cidA-1tkiA:
undetectable
6cidB-1tkiA:
undetectable		 6cidA-1tkiA:
13.38
6cidB-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1tki TITIN
(Homo
sapiens) 		4 / 7 TRP A 277
PHE A 254
GLU A 250
VAL A 122
 None
 1.49A 6cidA-1tkiA:
undetectable
6cidB-1tkiA:
undetectable		 6cidA-1tkiA:
13.38
6cidB-1tkiA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1tki TITIN
(Homo
sapiens) 		4 / 7 ALA A 269
ASP A 144
ILE A 145
ILE A 150
 None
 0.79A 6fbnA-1tkiA:
undetectable		 6fbnA-1tkiA:
21.72