SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tlg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 1t3rA-1tlgA:
undetectable		 1t3rA-1tlgA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 1t7iA-1tlgA:
undetectable		 1t7iA-1tlgA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 11 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.88A 1t7jA-1tlgA:
undetectable		 1t7jA-1tlgA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 9 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.86A 2idwB-1tlgA:
undetectable		 2idwB-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.89A 2ieoA-1tlgA:
undetectable		 2ieoA-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.84A 2nmzA-1tlgA:
undetectable		 2nmzA-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.86A 2q63A-1tlgA:
undetectable		 2q63A-1tlgA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 3bvbB-1tlgA:
undetectable		 3bvbB-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 9 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.86A 3ektA-1tlgA:
undetectable		 3ektA-1tlgA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 11 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.89A 3ektC-1tlgA:
undetectable		 3ektC-1tlgA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.83A 3ekvA-1tlgA:
undetectable		 3ekvA-1tlgA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		4 / 8 GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.58A 3em6A-1tlgA:
undetectable		 3em6A-1tlgA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 9 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.91A 3gguB-1tlgA:
undetectable		 3gguB-1tlgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 3jw2A-1tlgA:
undetectable		 3jw2A-1tlgA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.83A 3jw2B-1tlgA:
undetectable		 3jw2B-1tlgA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 3lzuB-1tlgA:
undetectable		 3lzuB-1tlgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.90A 3lzvA-1tlgA:
undetectable		 3lzvA-1tlgA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.86A 3ndtA-1tlgA:
undetectable		 3ndtA-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.87A 3oxwA-1tlgA:
undetectable		 3oxwA-1tlgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.88A 3oxwC-1tlgA:
undetectable		 3oxwC-1tlgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 3oy4B-1tlgA:
undetectable		 3oy4B-1tlgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		4 / 8 GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.49A 3so9A-1tlgA:
undetectable		 3so9A-1tlgA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 3tl9A-1tlgA:
undetectable		 3tl9A-1tlgA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 4dqbB-1tlgA:
undetectable		 4dqbB-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 9 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.87A 4dqcB-1tlgA:
undetectable		 4dqcB-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.87A 4dqeB-1tlgA:
undetectable		 4dqeB-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.90A 4dqfB-1tlgA:
undetectable		 4dqfB-1tlgA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 4dqhB-1tlgA:
undetectable		 4dqhB-1tlgA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.87A 4ll3B-1tlgA:
undetectable		 4ll3B-1tlgA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.89A 4ll3A-1tlgA:
undetectable		 4ll3A-1tlgA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.89A 4njtB-1tlgA:
undetectable		 4njtB-1tlgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 9 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.84A 4q1wA-1tlgA:
undetectable		 4q1wA-1tlgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 11 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 4q1xA-1tlgA:
undetectable		 4q1xA-1tlgA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 10 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 4q1yA-1tlgA:
undetectable		 4q1yA-1tlgA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		4 / 8 PHE A  67
SER A  88
ASP A  52
TYR A 103
 None
GAL  A 126 ( 3.1A)
None
None
 1.10A 4qb9D-1tlgA:
undetectable		 4qb9D-1tlgA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		4 / 7 GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.59A 5kqyB-1tlgA:
undetectable		 5kqyB-1tlgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		4 / 8 GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.61A 5kr1B-1tlgA:
undetectable		 5kr1B-1tlgA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LOG_A_LDPA1004_1
(PUTATIVE
O-METHYLTRANSFERASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		4 / 6 ASP A 107
ASP A 108
ASN A  89
TRP A  93
 GAL  A 126 (-2.5A)
CA  A 201 (-3.0A)
CA  A 201 (-3.2A)
None
 1.26A 5logA-1tlgA:
undetectable		 5logA-1tlgA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1tlg POLYANDROCARPA
LECTIN
(Polyandrocarpa
misakiensis) 		5 / 12 LEU A  81
GLY A  56
ALA A  57
ASP A  58
GLY A  72
 None
 0.85A 5t2zB-1tlgA:
undetectable		 5t2zB-1tlgA:
18.66