SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 1tlv TRANSCRIPTION
ANTITERMINATOR LICT
(Bacillus
subtilis) 		4 / 6 ILE A 175
TYR A 249
TYR A 254
PHE A 216
 None
 0.94A 4g10A-1tlvA:
undetectable		 4g10A-1tlvA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1tlv TRANSCRIPTION
ANTITERMINATOR LICT
(Bacillus
subtilis) 		4 / 4 LEU A 158
ILE A 160
GLY A 154
ILE A 132
 None
 0.89A 5dzk3-1tlvA:
undetectable
5dzkm-1tlvA:
undetectable		 5dzk3-1tlvA:
20.00
5dzkm-1tlvA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1tlv TRANSCRIPTION
ANTITERMINATOR LICT
(Bacillus
subtilis) 		4 / 5 ILE A 160
GLY A 154
ILE A 132
LEU A 158
 None
 0.86A 5dzkB-1tlvA:
undetectable
5dzkI-1tlvA:
undetectable
5dzkW-1tlvA:
undetectable		 5dzkB-1tlvA:
20.59
5dzkI-1tlvA:
23.14
5dzkW-1tlvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1tlv TRANSCRIPTION
ANTITERMINATOR LICT
(Bacillus
subtilis) 		4 / 4 ILE A 160
GLY A 154
ILE A 132
LEU A 158
 None
 0.85A 5dzkl-1tlvA:
undetectable
5dzkz-1tlvA:
undetectable		 5dzkl-1tlvA:
23.14
5dzkz-1tlvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1tlv TRANSCRIPTION
ANTITERMINATOR LICT
(Bacillus
subtilis) 		3 / 3 PHE A 210
ARG A 214
GLN A 213
 None
 1.15A 6g1pB-1tlvA:
0.0		 6g1pB-1tlvA:
21.27