SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tme'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		4 / 5 TYR 1  37
TYR 1 238
PHE 1 120
PRO 1 119
 None
 1.15A 1dfoB-1tme1:
undetectable		 1dfoB-1tme1:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		4 / 5 TYR 1  37
TYR 1 238
PHE 1 120
PRO 1 119
 None
 1.15A 1dfoA-1tme1:
undetectable		 1dfoA-1tme1:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		4 / 5 TYR 1  37
TYR 1 238
PHE 1 120
PRO 1 119
 None
 1.16A 1dfoD-1tme1:
undetectable		 1dfoD-1tme1:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		4 / 5 TYR 1  37
TYR 1 238
PHE 1 120
PRO 1 119
 None
 1.15A 1dfoC-1tme1:
undetectable		 1dfoC-1tme1:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		3 / 3 GLN 2 183
TYR 2 167
ARG 2 168
 None
 0.95A 1gtbA-1tme2:
undetectable		 1gtbA-1tme2:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		5 / 12 ALA 1 219
PHE 1 201
ASN 2 222
VAL 1 195
TYR 1 189
 None
 1.15A 1u72A-1tme1:
undetectable		 1u72A-1tme1:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		3 / 3 LYS 1 242
ARG 1  32
VAL 1  33
 None
 0.91A 2r2vC-1tme1:
0.0
2r2vD-1tme1:
0.0		 2r2vC-1tme1:
12.43
2r2vD-1tme1:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		4 / 6 TYR 1  37
TYR 1 238
PHE 1 120
PRO 1 119
 None
 1.19A 2vmyA-1tme1:
undetectable		 2vmyA-1tme1:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		5 / 11 LEU 2 194
ILE 2 193
PHE 2 230
SER 2 231
VAL 2 112
 None
 1.23A 3a9eB-1tme2:
undetectable		 3a9eB-1tme2:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		4 / 5 PRO 2 190
THR 2  29
VAL 2  30
GLY 2  31
 None
 1.14A 3elzA-1tme2:
undetectable		 3elzA-1tme2:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		3 / 3 GLY 2  90
PRO 2  85
LEU 2 100
 None
 0.62A 3hcpB-1tme2:
undetectable		 3hcpB-1tme2:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
(Cardiovirus
B) 		4 / 8 PHE 1 221
ILE 1  43
TYR 1 238
PHE 1 114
 None
 1.01A 3rqwI-1tme1:
undetectable
3rqwJ-1tme1:
undetectable		 3rqwI-1tme1:
21.86
3rqwJ-1tme1:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		3 / 3 PRO 1  72
LEU 1  73
HIS 2 180
 None
 0.68A 4pevA-1tme1:
undetectable		 4pevA-1tme1:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B) 		4 / 8 GLY 2  37
CYH 2  34
GLY 2  35
GLU 2 205
 None
 0.74A 5vw5A-1tme2:
undetectable		 5vw5A-1tme2:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP1)
THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)
(Cardiovirus
B;
Cardiovirus
B) 		4 / 6 GLU 2 146
LYS 1 211
PHE 1 213
VAL 1 215
 None
 1.24A 6fgdA-1tme2:
undetectable		 6fgdA-1tme2:
20.85