SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VPO_H_TESH1010_1 (ANTI-TESTOSTERONE (HEAVY CHAIN) ANTI-TESTOSTERONE (LIGHT CHAIN))	1tmf	THEILER'S MURINE ENCEPHALOMYELITIS VIRUS (SUBUNIT VP3) (Cardiovirus B)	5 / 12	SER 3 206 GLY 3 123 LEU 3 196 PHE 3 125 VAL 3 114	None	1.24A	1vpoH-1tmf3: 0.9 1vpoL-1tmf3: 1.1	1vpoH-1tmf3: 21.34 1vpoL-1tmf3: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CCF_A_BEZA261_0 (CYCLOPROPANE-FATTY-A CYL-PHOSPHOLIPID SYNTHASE)	1tmf	THEILER'S MURINE ENCEPHALOMYELITIS VIRUS (SUBUNIT VP3) (Cardiovirus B)	4 / 8	GLY 3 55 ASN 3 56 PHE 3 113 TYR 3 81	None	1.42A	3ccfA-1tmf3: undetectable	3ccfA-1tmf3: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5SYJ_B_NIZB809_1 (CATALASE-PEROXIDASE)	1tmf	THEILER'S MURINE ENCEPHALOMYELITIS VIRUS (SUBUNIT VP3) (Cardiovirus B)	4 / 8	GLY 3 123 GLN 3 192 LEU 3 196 THR 3 194	None	0.90A	5syjB-1tmf3: undetectable	5syjB-1tmf3: 14.56