SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 1tn3 TETRANECTIN
(Homo
sapiens) 		4 / 6 LEU A 112
ASN A 135
SER A  85
PHE A  61
 None
 1.49A 3i9jB-1tn3A:
undetectable		 3i9jB-1tn3A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 1tn3 TETRANECTIN
(Homo
sapiens) 		5 / 10 GLY A 105
GLU A 107
LEU A 172
SER A 156
ALA A 159
 None
 1.23A 4wnuD-1tn3A:
undetectable		 4wnuD-1tn3A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1tn3 TETRANECTIN
(Homo
sapiens) 		3 / 3 GLY A 147
THR A 149
GLU A 150
 CA  A 182 ( 4.1A)
None
CA  A 183 ( 3.1A)
 0.54A 6b58A-1tn3A:
undetectable		 6b58A-1tn3A:
13.20