SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.95A 1c9sN-1tnuB:
undetectable
1c9sO-1tnuB:
undetectable		 1c9sN-1tnuB:
12.68
1c9sO-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1c9sP-1tnuB:
0.0
1c9sQ-1tnuB:
0.0		 1c9sP-1tnuB:
12.68
1c9sQ-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 9 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.98A 1c9sQ-1tnuB:
0.0
1c9sR-1tnuB:
undetectable		 1c9sQ-1tnuB:
12.68
1c9sR-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.97A 1c9sL-1tnuB:
undetectable
1c9sV-1tnuB:
undetectable		 1c9sL-1tnuB:
12.68
1c9sV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 5 PHE B 224
TYR B 176
LEU B 232
VAL B 340
 None
 1.44A 1dz6A-1tnuB:
0.0		 1dz6A-1tnuB:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 8 TYR B 272
VAL B 276
GLY B 221
GLY B 220
 None
None
MGM  B 379 ( 3.9A)
None
 0.84A 1ekjE-1tnuB:
undetectable
1ekjF-1tnuB:
undetectable		 1ekjE-1tnuB:
20.78
1ekjF-1tnuB:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 9 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.98A 1gtfD-1tnuB:
0.0
1gtfE-1tnuB:
0.0		 1gtfD-1tnuB:
12.68
1gtfE-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 1gtfJ-1tnuB:
undetectable
1gtfK-1tnuB:
undetectable		 1gtfJ-1tnuB:
12.68
1gtfK-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1gtfQ-1tnuB:
0.0
1gtfR-1tnuB:
undetectable		 1gtfQ-1tnuB:
12.68
1gtfR-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 9 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1gtfR-1tnuB:
undetectable
1gtfS-1tnuB:
undetectable		 1gtfR-1tnuB:
12.68
1gtfS-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1gtfS-1tnuB:
undetectable
1gtfT-1tnuB:
undetectable		 1gtfS-1tnuB:
12.68
1gtfT-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 7 LEU B 354
LEU B 135
GLY B 136
LEU B 139
 None
 0.95A 1gtiA-1tnuB:
1.8		 1gtiA-1tnuB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.97A 1gtnT-1tnuB:
undetectable
1gtnU-1tnuB:
undetectable		 1gtnT-1tnuB:
12.68
1gtnU-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.95A 1gtnL-1tnuB:
undetectable
1gtnV-1tnuB:
undetectable		 1gtnL-1tnuB:
12.68
1gtnV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 CYH B 271
THR B 127
SER B  56
VAL B 346
ALA B 319
 ZN  B 378 (-2.2A)
MGM  B 379 ( 4.6A)
None
None
None
 1.23A 1nw5A-1tnuB:
undetectable		 1nw5A-1tnuB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 1.02A 1utdE-1tnuB:
undetectable
1utdF-1tnuB:
0.0		 1utdE-1tnuB:
12.68
1utdF-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 1.03A 1utdH-1tnuB:
undetectable
1utdI-1tnuB:
0.0		 1utdH-1tnuB:
12.68
1utdI-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.95A 1utdL-1tnuB:
undetectable
1utdM-1tnuB:
undetectable		 1utdL-1tnuB:
12.68
1utdM-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.99A 1utdO-1tnuB:
undetectable
1utdP-1tnuB:
undetectable		 1utdO-1tnuB:
12.68
1utdP-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.96A 1utdP-1tnuB:
undetectable
1utdQ-1tnuB:
undetectable		 1utdP-1tnuB:
12.68
1utdQ-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.98A 1utdS-1tnuB:
undetectable
1utdT-1tnuB:
undetectable		 1utdS-1tnuB:
12.68
1utdT-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 209
HIS B 219
THR B 223
ILE B 248
GLY B 262
 None
MGM  B 379 (-3.7A)
None
None
None
 0.94A 1utdU-1tnuB:
undetectable
1utdV-1tnuB:
undetectable		 1utdU-1tnuB:
12.68
1utdV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 11 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 0.97A 1utdL-1tnuB:
undetectable
1utdV-1tnuB:
undetectable		 1utdL-1tnuB:
12.68
1utdV-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 4 GLY B 226
SER B 203
VAL B 175
LEU B 230
 None
 1.17A 1yajB-1tnuB:
undetectable		 1yajB-1tnuB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 7 THR B 350
TYR B 176
PHE B  52
LEU B 232
 None
 1.05A 2hzqA-1tnuB:
undetectable		 2hzqA-1tnuB:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		3 / 3 GLY B 159
ASP B 158
SER B 198
 None
 0.74A 2qhfA-1tnuB:
undetectable		 2qhfA-1tnuB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 6 LEU B 344
LEU B 232
SER B 229
CYH B 180
 None
 0.87A 3aiaA-1tnuB:
undetectable		 3aiaA-1tnuB:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 7 LEU B  58
ARG B  27
ARG B  31
GLY B 308
 None
 0.95A 3hcrB-1tnuB:
undetectable		 3hcrB-1tnuB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 MET B 233
LEU B 230
ALA B 228
LEU B 210
ILE B 197
 None
 1.21A 3olsB-1tnuB:
undetectable		 3olsB-1tnuB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 5 PHE B  20
ILE B 337
GLY B 325
HIS B  25
 None
 0.74A 3r0lD-1tnuB:
undetectable		 3r0lD-1tnuB:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 VAL B 340
ILE B 227
GLY B 277
ALA B 343
ALA B 228
 None
 0.90A 3sufD-1tnuB:
undetectable		 3sufD-1tnuB:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 PHE B  20
PHE B  29
ILE B 326
GLY B 325
PHE B  28
 None
 1.33A 3t3rD-1tnuB:
0.0		 3t3rD-1tnuB:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 8 TYR B 183
HIS B 341
TYR B 176
LEU B 282
 None
 1.22A 3uzzB-1tnuB:
undetectable		 3uzzB-1tnuB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 7 ILE B 298
GLY B 325
SER B 273
PHE B 286
LEU B 331
 None
 1.33A 3v7pA-1tnuB:
undetectable		 3v7pA-1tnuB:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 6 GLU B 334
ILE B 337
HIS B 321
VAL B 268
 None
None
ZN  B 378 (-3.4A)
None
 1.24A 4a97I-1tnuB:
undetectable		 4a97I-1tnuB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 CYH B 225
ALA B 278
PHE B 274
LEU B  48
PHE B  52
 MGM  B 379 ( 3.9A)
None
None
None
None
 1.43A 4iaqA-1tnuB:
undetectable		 4iaqA-1tnuB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		3 / 3 VAL B 346
SER B 347
THR B 350
 None
 0.44A 4luhA-1tnuB:
undetectable		 4luhA-1tnuB:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		3 / 3 ASP B 269
TYR B 272
TRP B 312
 ZN  B 378 (-2.1A)
None
None
 1.32A 4p7nA-1tnuB:
undetectable		 4p7nA-1tnuB:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.04A 5eevA-1tnuB:
undetectable
5eevB-1tnuB:
undetectable		 5eevA-1tnuB:
12.68
5eevB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.04A 5eewA-1tnuB:
undetectable
5eewB-1tnuB:
undetectable		 5eewA-1tnuB:
12.68
5eewB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.04A 5eexA-1tnuB:
undetectable
5eexB-1tnuB:
undetectable		 5eexA-1tnuB:
12.68
5eexB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5eeyA-1tnuB:
undetectable
5eeyB-1tnuB:
undetectable		 5eeyA-1tnuB:
12.68
5eeyB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5eezA-1tnuB:
0.0
5eezB-1tnuB:
undetectable		 5eezA-1tnuB:
12.68
5eezB-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef0A-1tnuB:
undetectable
5ef0B-1tnuB:
undetectable		 5ef0A-1tnuB:
12.68
5ef0B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef1A-1tnuB:
undetectable
5ef1B-1tnuB:
undetectable		 5ef1A-1tnuB:
12.68
5ef1B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef2A-1tnuB:
undetectable
5ef2B-1tnuB:
undetectable		 5ef2A-1tnuB:
12.68
5ef2B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B 262
GLY B 209
HIS B 219
THR B 223
ILE B 248
 None
None
MGM  B 379 (-3.7A)
None
None
 1.03A 5ef3A-1tnuB:
undetectable
5ef3B-1tnuB:
undetectable		 5ef3A-1tnuB:
12.68
5ef3B-1tnuB:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 5 SER B 108
GLN B  80
LEU B 132
PHE B  95
 None
 1.44A 5evyX-1tnuB:
undetectable		 5evyX-1tnuB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 8 ILE B 133
VAL B  26
ILE B 326
ILE B 337
ASP B  62
 None
 1.21A 5hi2A-1tnuB:
undetectable		 5hi2A-1tnuB:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B  94
GLY B 120
SER B 119
ARG B  92
GLU B 166
 None
 1.16A 5hwkA-1tnuB:
0.0		 5hwkA-1tnuB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 10 GLY B  94
GLY B 120
SER B 119
ARG B  92
GLU B 166
 None
 1.16A 5hwkB-1tnuB:
undetectable		 5hwkB-1tnuB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 4 LEU B 101
GLY B 102
SER B  99
SER B  98
 None
 0.96A 5uunA-1tnuB:
undetectable		 5uunA-1tnuB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 4 LEU B 101
GLY B 102
SER B  99
SER B  98
 None
 0.95A 5uunB-1tnuB:
undetectable		 5uunB-1tnuB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		4 / 7 GLN B 155
GLY B 190
ILE B 181
GLN B  80
 None
 1.07A 5vlmC-1tnuB:
0.8		 5vlmC-1tnuB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT
(Rattus
norvegicus) 		5 / 12 PHE B 324
GLY B 328
CYH B 327
ILE B 337
TYR B 176
 None
 1.00A 6md4A-1tnuB:
0.0		 6md4A-1tnuB:
12.36