SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1to3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 ALA A 274
VAL A 255
TRP A 256
 None
 0.90A 1av2A-1to3A:
undetectable
1av2B-1to3A:
undetectable		 1av2A-1to3A:
6.40
1av2B-1to3A:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 TRP A 256
ALA A 274
VAL A 255
 None
 0.93A 1av2C-1to3A:
undetectable
1av2D-1to3A:
undetectable		 1av2C-1to3A:
6.40
1av2D-1to3A:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.70A 1hsgB-1to3A:
undetectable		 1hsgB-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 ASP A  91
LEU A 123
LEU A 125
 None
 0.78A 1ikeA-1to3A:
undetectable		 1ikeA-1to3A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 4 ALA A 176
ARG A 173
GLN A 175
GLU A 174
 BR  A 309 ( 4.1A)
None
PO4  A 303 ( 4.7A)
None
 1.14A 1lqtB-1to3A:
0.8		 1lqtB-1to3A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 4 ALA A 176
ARG A 173
GLN A 175
GLU A 174
 BR  A 309 ( 4.1A)
None
PO4  A 303 ( 4.7A)
None
 1.13A 1lquB-1to3A:
undetectable		 1lquB-1to3A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 ASP A  91
LEU A 123
LEU A 125
 None
 0.76A 1np1B-1to3A:
0.0		 1np1B-1to3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.72A 1ohrA-1to3A:
undetectable		 1ohrA-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 ARG A 138
LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 1.49A 1rl8B-1to3A:
undetectable		 1rl8B-1to3A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 ALA A 244
GLU A 243
LEU A 208
LEU A 198
ILE A 177
 None
 1.06A 1s9pA-1to3A:
undetectable		 1s9pA-1to3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 ALA A 244
GLU A 243
LEU A 208
LEU A 198
ILE A 177
 None
 1.09A 1s9pD-1to3A:
undetectable		 1s9pD-1to3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.66A 1sdtB-1to3A:
undetectable		 1sdtB-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.71A 1sduB-1to3A:
undetectable		 1sduB-1to3A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 ALA A 274
VAL A 255
TRP A 256
 None
 0.90A 1w5uA-1to3A:
undetectable
1w5uB-1to3A:
undetectable		 1w5uA-1to3A:
6.40
1w5uB-1to3A:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 TRP A 256
ALA A 274
VAL A 255
 None
 0.86A 1w5uA-1to3A:
undetectable
1w5uB-1to3A:
undetectable		 1w5uA-1to3A:
6.40
1w5uB-1to3A:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 4 LEU A  19
SER A  57
TYR A  59
LEU A 277
 None
 1.14A 1xz1A-1to3A:
undetectable		 1xz1A-1to3A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 4 LEU A  19
SER A  57
TYR A  59
LEU A 277
 None
 1.13A 1xz3A-1to3A:
undetectable		 1xz3A-1to3A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.67A 2aquA-1to3A:
undetectable		 2aquA-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.68A 2aquB-1to3A:
undetectable		 2aquB-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.69A 2avoB-1to3A:
undetectable		 2avoB-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.71A 2avvE-1to3A:
undetectable		 2avvE-1to3A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.86A 2avvE-1to3A:
undetectable		 2avvE-1to3A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.76A 2bpxB-1to3A:
undetectable		 2bpxB-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.65A 2f80A-1to3A:
undetectable		 2f80A-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.81A 2f80A-1to3A:
undetectable		 2f80A-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.68A 2f8gA-1to3A:
undetectable		 2f8gA-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.83A 2f8gA-1to3A:
undetectable		 2f8gA-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.90A 2f8gB-1to3A:
undetectable		 2f8gB-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.73A 2fxeA-1to3A:
undetectable		 2fxeA-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.76A 2fxeB-1to3A:
undetectable		 2fxeB-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 5 ASP A  42
LEU A  45
MET A  27
ARG A  28
 None
 1.39A 2gj5A-1to3A:
0.0		 2gj5A-1to3A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.68A 2hs2B-1to3A:
undetectable		 2hs2B-1to3A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.84A 2hs2B-1to3A:
undetectable		 2hs2B-1to3A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.92A 2idwB-1to3A:
undetectable		 2idwB-1to3A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.89A 2ienA-1to3A:
undetectable		 2ienA-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.77A 2ieoA-1to3A:
undetectable		 2ieoA-1to3A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 ALA A 274
VAL A 255
TRP A 256
 None
 0.96A 2izqA-1to3A:
undetectable
2izqB-1to3A:
undetectable		 2izqA-1to3A:
6.40
2izqB-1to3A:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.74A 2o4kB-1to3A:
undetectable		 2o4kB-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.86A 2o4lB-1to3A:
undetectable		 2o4lB-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.71A 2o4sA-1to3A:
undetectable		 2o4sA-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.69A 2o4sB-1to3A:
undetectable		 2o4sB-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.84A 2q63A-1to3A:
undetectable		 2q63A-1to3A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.81A 2q64A-1to3A:
undetectable		 2q64A-1to3A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.82A 2q64B-1to3A:
undetectable		 2q64B-1to3A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.82A 2qakA-1to3A:
undetectable		 2qakA-1to3A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.67A 2r5pB-1to3A:
undetectable		 2r5pB-1to3A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.67A 2r5pD-1to3A:
undetectable		 2r5pD-1to3A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.64A 2r5qB-1to3A:
undetectable		 2r5qB-1to3A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.78A 2rkfA-1to3A:
undetectable		 2rkfA-1to3A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.79A 2rkfB-1to3A:
undetectable		 2rkfB-1to3A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.78A 2rkgA-1to3A:
undetectable		 2rkgA-1to3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.78A 2rkgB-1to3A:
undetectable		 2rkgB-1to3A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.66A 2z54A-1to3A:
undetectable		 2z54A-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.68A 2z54B-1to3A:
undetectable		 2z54B-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.83A 3bvbA-1to3A:
undetectable		 3bvbA-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.81A 3bvbB-1to3A:
undetectable		 3bvbB-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.85A 3bvbB-1to3A:
undetectable		 3bvbB-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.67A 3d1xA-1to3A:
undetectable		 3d1xA-1to3A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.79A 3d1yA-1to3A:
undetectable		 3d1yA-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.74A 3ekyA-1to3A:
undetectable		 3ekyA-1to3A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.75A 3el1B-1to3A:
undetectable		 3el1B-1to3A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.81A 3em3A-1to3A:
undetectable		 3em3A-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.72A 3em4A-1to3A:
undetectable		 3em4A-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 ALA A 189
ASP A 190
LEU A 148
VAL A 127
ILE A 158
 None
 1.07A 3em4B-1to3A:
undetectable		 3em4B-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.71A 3em4U-1to3A:
undetectable		 3em4U-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 216
LEU A 214
GLN A 212
ILE A 178
ALA A 210
 None
 1.05A 3gwvA-1to3A:
undetectable		 3gwvA-1to3A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.81A 3jvyA-1to3A:
undetectable		 3jvyA-1to3A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.86A 3jvyB-1to3A:
undetectable		 3jvyB-1to3A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.85A 3jw2A-1to3A:
undetectable		 3jw2A-1to3A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.88A 3jw2B-1to3A:
undetectable		 3jw2B-1to3A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.88A 3k4vA-1to3A:
undetectable		 3k4vA-1to3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 TRP A 256
ALA A 274
VAL A 255
 None
 0.94A 3l8lC-1to3A:
undetectable
3l8lD-1to3A:
undetectable		 3l8lC-1to3A:
6.40
3l8lD-1to3A:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.78A 3lzsA-1to3A:
undetectable		 3lzsA-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.92A 3lzuB-1to3A:
undetectable		 3lzuB-1to3A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.90A 3lzvA-1to3A:
undetectable		 3lzvA-1to3A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.83A 3mwsA-1to3A:
undetectable		 3mwsA-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.89A 3ndtA-1to3A:
undetectable		 3ndtA-1to3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.80A 3ndtB-1to3A:
undetectable		 3ndtB-1to3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.81A 3nduA-1to3A:
undetectable		 3nduA-1to3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.80A 3nduB-1to3A:
undetectable		 3nduB-1to3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.68A 3ndwA-1to3A:
undetectable		 3ndwA-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.73A 3ndxB-1to3A:
undetectable		 3ndxB-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.78A 3nu5A-1to3A:
undetectable		 3nu5A-1to3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.81A 3oxvA-1to3A:
undetectable		 3oxvA-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.80A 3oxwA-1to3A:
undetectable		 3oxwA-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.76A 3oxwC-1to3A:
undetectable		 3oxwC-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.74A 3oxxC-1to3A:
undetectable		 3oxxC-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 LEU A 184
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.88A 3oxxD-1to3A:
undetectable		 3oxxD-1to3A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.91A 3oy4B-1to3A:
undetectable		 3oy4B-1to3A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 PRO A 197
LEU A 198
ALA A 210
THR A 209
LEU A 208
 None
 1.02A 3r9cA-1to3A:
undetectable		 3r9cA-1to3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 6 LEU A  19
SER A  57
TYR A  59
ALA A  81
LEU A 277
 None
 1.16A 3ravA-1to3A:
undetectable		 3ravA-1to3A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.88A 3s45B-1to3A:
undetectable		 3s45B-1to3A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 ALA A 189
VAL A 142
GLY A 185
ILE A 218
PRO A 160
 None
 0.91A 3spkA-1to3A:
undetectable		 3spkA-1to3A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.85A 3tkgA-1to3A:
undetectable		 3tkgA-1to3A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.77A 3tkwB-1to3A:
undetectable		 3tkwB-1to3A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.90A 3tl9A-1to3A:
undetectable		 3tl9A-1to3A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
VAL A 127
ILE A 158
 None
 0.80A 3tl9B-1to3A:
undetectable		 3tl9B-1to3A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.85A 4dqbB-1to3A:
undetectable		 4dqbB-1to3A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.86A 4dqeB-1to3A:
undetectable		 4dqeB-1to3A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.86A 4dqhB-1to3A:
undetectable		 4dqhB-1to3A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 6 PHE A  48
ALA A  52
GLY A 252
VAL A 255
 None
None
PO4  A 305 (-3.5A)
None
 0.92A 4dubA-1to3A:
undetectable		 4dubA-1to3A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 6 PHE A  48
ALA A  52
GLY A 252
VAL A 255
 None
None
PO4  A 305 (-3.5A)
None
 0.95A 4dubB-1to3A:
undetectable		 4dubB-1to3A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.77A 4hlaA-1to3A:
undetectable		 4hlaA-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.69A 4hlaB-1to3A:
undetectable		 4hlaB-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.76A 4hlaB-1to3A:
undetectable		 4hlaB-1to3A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		6 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.86A 4jecA-1to3A:
undetectable		 4jecA-1to3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 ALA A 189
VAL A 142
GLY A 185
ILE A 218
PRO A 160
 None
 0.95A 4njuB-1to3A:
undetectable		 4njuB-1to3A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 ALA A 189
VAL A 142
GLY A 185
ILE A 218
PRO A 160
 None
 0.96A 4njuD-1to3A:
undetectable		 4njuD-1to3A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.92A 4q1wA-1to3A:
undetectable		 4q1wA-1to3A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 11 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.89A 4q1xA-1to3A:
undetectable		 4q1xA-1to3A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 LEU A 184
GLY A 188
ALA A 189
ASP A 190
VAL A 127
 None
 0.88A 4q1yA-1to3A:
undetectable		 4q1yA-1to3A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 LEU A 106
LEU A 184
ARG A 138
LEU A 125
ILE A 158
 None
 1.09A 4ubsA-1to3A:
undetectable		 4ubsA-1to3A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.82A 5e5jA-1to3A:
undetectable		 5e5jA-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.80A 5e5kA-1to3A:
undetectable		 5e5kA-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 5 TRP A 129
LEU A 126
PRO A 160
LEU A 106
 None
 1.46A 5eshA-1to3A:
0.0		 5eshA-1to3A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A  27
GLN A  23
ARG A  24
 None
PO4  A 304 (-3.9A)
None
 0.97A 5ewzB-1to3A:
undetectable		 5ewzB-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A 141
GLN A 137
ARG A 138
 None
 1.04A 5ewzB-1to3A:
undetectable		 5ewzB-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 GLY A 188
ALA A 189
ASP A 190
VAL A 127
ILE A 158
 None
 0.73A 5kqxA-1to3A:
undetectable		 5kqxA-1to3A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A  27
GLN A  23
ARG A  24
 None
PO4  A 304 (-3.9A)
None
 0.86A 5m35B-1to3A:
0.0		 5m35B-1to3A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A 141
GLN A 137
ARG A 138
 None
 1.00A 5m35B-1to3A:
0.0		 5m35B-1to3A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A  27
GLN A  23
ARG A  24
 None
PO4  A 304 (-3.9A)
None
 0.84A 5m36A-1to3A:
undetectable		 5m36A-1to3A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A 141
GLN A 137
ARG A 138
 None
 0.99A 5m36A-1to3A:
undetectable		 5m36A-1to3A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		4 / 7 GLY A 153
LYS A 121
ALA A 120
ASP A   8
 None
 0.87A 5mvsA-1to3A:
undetectable		 5mvsA-1to3A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.89A 5t2zB-1to3A:
undetectable		 5t2zB-1to3A:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 LEU A 184
GLY A 188
ALA A 189
ASP A 190
ILE A 158
 None
 0.84A 5t8hA-1to3A:
undetectable		 5t8hA-1to3A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 ALA A 244
LEU A 208
LEU A 207
ILE A 177
LEU A 198
 None
 1.01A 5toaA-1to3A:
undetectable		 5toaA-1to3A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 9 ALA A  17
SER A  61
GLY A 281
ALA A  12
SER A  13
 None
None
None
BR  A 314 (-4.1A)
None
 1.22A 6bklE-1to3A:
undetectable
6bklF-1to3A:
undetectable
6bklG-1to3A:
undetectable
6bklH-1to3A:
undetectable		 6bklE-1to3A:
6.71
6bklF-1to3A:
6.71
6bklG-1to3A:
6.71
6bklH-1to3A:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 GLY A 188
ASP A 186
ILE A 218
 None
 0.56A 6dgxB-1to3A:
undetectable		 6dgxB-1to3A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A  27
GLN A  23
ARG A  24
 None
PO4  A 304 (-3.9A)
None
 0.81A 6fn9A-1to3A:
0.0		 6fn9A-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A 141
GLN A 137
ARG A 138
 None
 0.97A 6fn9A-1to3A:
0.0		 6fn9A-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A  27
GLN A  23
ARG A  24
 None
PO4  A 304 (-3.9A)
None
 0.83A 6fnaB-1to3A:
undetectable		 6fnaB-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A 141
GLN A 137
ARG A 138
 None
 1.02A 6fnaB-1to3A:
undetectable		 6fnaB-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A  27
GLN A  23
ARG A  24
 None
PO4  A 304 (-3.9A)
None
 0.83A 6fnbA-1to3A:
undetectable		 6fnbA-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		3 / 3 MET A 141
GLN A 137
ARG A 138
 None
 0.97A 6fnbA-1to3A:
undetectable		 6fnbA-1to3A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 10 PHE A  16
MET A  18
ALA A  17
TYR A  59
VAL A 284
 None
 1.33A 6hu9C-1to3A:
undetectable		 6hu9C-1to3A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 1to3 PUTATIVE ALDOLASE
YIHT
(Salmonella
enterica) 		5 / 12 PHE A  16
MET A  18
ALA A  17
TYR A  59
VAL A 284
 None
 1.35A 6hu9N-1to3A:
undetectable		 6hu9N-1to3A:
20.56