SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1to6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.80A 1c6yB-1to6A:
undetectable		 1c6yB-1to6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.89A 1hshC-1to6A:
undetectable		 1hshC-1to6A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 8 ALA A 334
GLY A 317
ILE A 337
PRO A   7
ILE A 283
 None
 1.29A 1hshD-1to6A:
undetectable		 1hshD-1to6A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A 188
GLY A 244
ALA A 135
SER A 136
GLY A  45
 None
SO4  A 373 (-3.5A)
None
None
None
 1.16A 1nbiA-1to6A:
3.3		 1nbiA-1to6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A 188
GLY A 244
ALA A 135
SER A 136
GLY A  44
 None
SO4  A 373 (-3.5A)
None
None
None
 1.14A 1nbiB-1to6A:
undetectable		 1nbiB-1to6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 140
ALA A 241
PHE A 227
PHE A 254
 None
 1.30A 1nw3A-1to6A:
undetectable		 1nw3A-1to6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 GLY A 132
GLU A  46
GLY A 133
ILE A 247
LEU A 119
 SO4  A 373 (-3.2A)
None
SO4  A 373 (-4.0A)
None
None
 1.16A 1p91A-1to6A:
undetectable		 1p91A-1to6A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 ALA A 144
GLY A 140
ASP A 138
ILE A 141
VAL A 131
 None
 1.18A 1pg2A-1to6A:
undetectable		 1pg2A-1to6A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.86A 1sdtB-1to6A:
undetectable		 1sdtB-1to6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.92A 1sduB-1to6A:
undetectable		 1sduB-1to6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.85A 1sdvB-1to6A:
undetectable		 1sdvB-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 8 ALA A 241
ILE A 224
GLY A 139
GLY A 140
ILE A 143
 None
 1.03A 1sguA-1to6A:
undetectable		 1sguA-1to6A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 8 ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 ( 4.2A)
None
None
None
 0.67A 1sh9A-1to6A:
undetectable		 1sh9A-1to6A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.81A 2f81B-1to6A:
undetectable		 2f81B-1to6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 ILE A 224
GLY A 142
THR A 109
LEU A 105
GLY A 139
 None
 1.21A 2fn1A-1to6A:
undetectable		 2fn1A-1to6A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.80A 2ienB-1to6A:
undetectable		 2ienB-1to6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.81A 2nmzA-1to6A:
undetectable		 2nmzA-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.92A 2q5kA-1to6A:
undetectable		 2q5kA-1to6A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.98A 2q64A-1to6A:
undetectable		 2q64A-1to6A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 7 ILE A  23
CYH A  36
LEU A 366
ILE A  31
 None
 0.75A 2q83A-1to6A:
undetectable		 2q83A-1to6A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 6 ILE A  23
CYH A  36
LEU A 366
ILE A  31
 None
 0.82A 2q83B-1to6A:
undetectable		 2q83B-1to6A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 1.02A 2qhcA-1to6A:
undetectable		 2qhcA-1to6A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.94A 2r5qD-1to6A:
undetectable		 2r5qD-1to6A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		3 / 3 GLY A 242
GLY A 250
GLY A 246
 None
 0.32A 3bogC-1to6A:
undetectable		 3bogC-1to6A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.78A 3d1zB-1to6A:
undetectable		 3d1zB-1to6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 8 GLY A 244
GLY A 246
GLY A 139
THR A 109
 SO4  A 373 (-3.5A)
None
None
None
 0.69A 3d41A-1to6A:
undetectable		 3d41A-1to6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.81A 3ekqA-1to6A:
undetectable		 3ekqA-1to6A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.83A 3ekvA-1to6A:
undetectable		 3ekvA-1to6A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.92A 3ekwA-1to6A:
undetectable		 3ekwA-1to6A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.99A 3ekyA-1to6A:
undetectable		 3ekyA-1to6A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 243
LEU A 196
THR A 109
ILE A 141
LEU A 166
 SO4  A 373 ( 4.2A)
None
None
None
None
 1.12A 3hj3D-1to6A:
undetectable		 3hj3D-1to6A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 317
GLY A 287
LEU A  14
SER A 352
ALA A 314
 None
SO4  A 374 (-3.0A)
None
None
None
 1.14A 3i5uB-1to6A:
4.0		 3i5uB-1to6A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.87A 3nduD-1to6A:
undetectable		 3nduD-1to6A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.97A 3ndwB-1to6A:
undetectable		 3ndwB-1to6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.87A 3nu4B-1to6A:
undetectable		 3nu4B-1to6A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 7 TYR A 128
GLN A  79
GLU A  81
ARG A 187
 None
 1.24A 3s3oA-1to6A:
undetectable		 3s3oA-1to6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 ILE A 315
GLY A 363
ILE A  31
ILE A   5
ILE A 283
 None
 0.99A 3s43A-1to6A:
undetectable		 3s43A-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.86A 3s43B-1to6A:
undetectable		 3s43B-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 ILE A 315
GLY A 363
ILE A  31
ILE A   5
ILE A 283
 None
 0.93A 3s45A-1to6A:
undetectable		 3s45A-1to6A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.90A 3s45B-1to6A:
undetectable		 3s45B-1to6A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.86A 3s53A-1to6A:
undetectable		 3s53A-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.88A 3s56A-1to6A:
undetectable		 3s56A-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.83A 3tkgC-1to6A:
undetectable		 3tkgC-1to6A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.96A 3ttpA-1to6A:
undetectable		 3ttpA-1to6A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.96A 3ttpB-1to6A:
undetectable		 3ttpB-1to6A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.95A 3uboB-1to6A:
6.0		 3uboB-1to6A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.81A 3ucbA-1to6A:
undetectable		 3ucbA-1to6A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.86A 3ucbB-1to6A:
undetectable		 3ucbB-1to6A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 8 GLY A 245
GLY A 246
SER A 136
ILE A 112
VAL A  92
 None
 0.96A 3v1nA-1to6A:
undetectable		 3v1nA-1to6A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A 141
GLY A 244
ALA A 243
GLY A 250
LEU A 251
 None
SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
 1.06A 4e1gB-1to6A:
undetectable		 4e1gB-1to6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.92A 4e3aA-1to6A:
5.5		 4e3aA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		3 / 3 PHE A 254
VAL A  88
ILE A 129
 None
 0.43A 4emaA-1to6A:
undetectable		 4emaA-1to6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 LEU A 251
ILE A 259
ILE A 247
GLY A 246
GLY A 242
 None
 0.99A 4fakA-1to6A:
2.9		 4fakA-1to6A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 249
GLY A 250
ILE A 247
VAL A 192
ILE A 188
 None
 0.92A 4fglA-1to6A:
5.9
4fglB-1to6A:
2.9		 4fglA-1to6A:
22.22
4fglB-1to6A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.91A 4hlaB-1to6A:
undetectable		 4hlaB-1to6A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4jksA-1to6A:
5.7		 4jksA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4jksB-1to6A:
5.5		 4jksB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4jkuA-1to6A:
6.1		 4jkuA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4jkuB-1to6A:
undetectable		 4jkuB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4k8cA-1to6A:
6.4		 4k8cA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4k8cB-1to6A:
undetectable		 4k8cB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.95A 4k8kA-1to6A:
undetectable		 4k8kA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.95A 4k8kB-1to6A:
5.7		 4k8kB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4k8pA-1to6A:
5.4		 4k8pA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4k8pB-1to6A:
5.6		 4k8pB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4k8tA-1to6A:
5.5		 4k8tA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4k8tB-1to6A:
5.7		 4k8tB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4k93A-1to6A:
6.4		 4k93A-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.95A 4k93B-1to6A:
5.4		 4k93B-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4k9cA-1to6A:
5.8		 4k9cA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4k9cB-1to6A:
5.7		 4k9cB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.95A 4k9iA-1to6A:
5.5		 4k9iA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.96A 4k9iB-1to6A:
5.6		 4k9iB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4kadA-1to6A:
6.4		 4kadA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.95A 4kadB-1to6A:
6.4		 4kadB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4kahA-1to6A:
6.1		 4kahA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4kahB-1to6A:
5.7		 4kahB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4kalA-1to6A:
undetectable		 4kalA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4kalB-1to6A:
5.7		 4kalB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4kanA-1to6A:
6.4		 4kanA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4kanB-1to6A:
5.5		 4kanB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4kbeA-1to6A:
6.3		 4kbeA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4kbeB-1to6A:
6.4		 4kbeB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 7 SER A 293
GLY A  42
GLY A  44
GLU A  87
 None
 0.87A 4koeA-1to6A:
undetectable
4koeB-1to6A:
undetectable
4koeD-1to6A:
4.8		 4koeA-1to6A:
21.51
4koeB-1to6A:
21.51
4koeD-1to6A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4lbgA-1to6A:
undetectable		 4lbgA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4lbgB-1to6A:
5.7		 4lbgB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4lbxA-1to6A:
undetectable		 4lbxA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4lbxB-1to6A:
undetectable		 4lbxB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4lc4A-1to6A:
undetectable		 4lc4A-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4lc4B-1to6A:
5.6		 4lc4B-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.93A 4lcaA-1to6A:
5.6		 4lcaA-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ASP A 138
GLY A 139
GLY A 246
SER A 136
THR A 134
 None
None
None
None
SO4  A 373 (-3.1A)
 0.94A 4lcaB-1to6A:
undetectable		 4lcaB-1to6A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.88A 4ll3A-1to6A:
undetectable		 4ll3A-1to6A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 9 ASP A 264
VAL A  41
GLY A 296
SER A 261
GLY A  44
 None
 1.35A 4mmeB-1to6A:
undetectable		 4mmeB-1to6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 LEU A 238
GLY A 240
VAL A 260
ILE A 247
VAL A  88
 None
 1.01A 4ok1A-1to6A:
0.0		 4ok1A-1to6A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 11 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.90A 4q1xA-1to6A:
undetectable		 4q1xA-1to6A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 10 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.89A 4q1yA-1to6A:
undetectable		 4q1yA-1to6A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 SER A 136
GLY A 244
ILE A 186
ALA A 255
GLY A 250
 None
SO4  A 373 (-3.5A)
None
None
None
 1.11A 4r29D-1to6A:
undetectable		 4r29D-1to6A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 8 ILE A 143
CYH A 252
LEU A 189
ILE A 129
 None
 0.94A 4xtaB-1to6A:
undetectable		 4xtaB-1to6A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 LEU A 119
ILE A 143
LEU A 147
VAL A  88
VAL A  92
 None
 1.00A 4y0qA-1to6A:
undetectable		 4y0qA-1to6A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		3 / 5 GLY A  42
GLY A  45
GLU A  87
 None
 0.43A 4z2eA-1to6A:
undetectable
4z2eD-1to6A:
undetectable		 4z2eA-1to6A:
20.24
4z2eD-1to6A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 7 GLY A  42
GLY A  44
GLU A  87
SER A 293
 None
 0.88A 4z53A-1to6A:
3.1
4z53B-1to6A:
2.6		 4z53A-1to6A:
19.52
4z53B-1to6A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 139
GLY A 246
GLY A 244
ALA A 223
LEU A 105
 None
None
SO4  A 373 (-3.5A)
None
None
 0.97A 5c0oF-1to6A:
2.6		 5c0oF-1to6A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 202
GLY A 249
GLY A 242
GLY A 240
LEU A 238
 None
 1.01A 5c0oH-1to6A:
undetectable		 5c0oH-1to6A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 5 PHE A  27
ILE A 315
GLY A 363
ILE A 283
 None
 0.78A 5dzkB-1to6A:
2.1
5dzkI-1to6A:
undetectable
5dzkW-1to6A:
undetectable		 5dzkB-1to6A:
19.30
5dzkI-1to6A:
19.57
5dzkW-1to6A:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A 112
GLY A 249
GLY A 142
GLY A 130
VAL A 131
 None
 0.98A 5i73A-1to6A:
undetectable		 5i73A-1to6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 THR A 109
ARG A 110
ILE A 112
GLY A 113
ILE A 116
 None
 0.40A 5ifuA-1to6A:
2.5		 5ifuA-1to6A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A 247
GLU A 114
PHE A 254
ALA A 253
ILE A 127
 None
 1.31A 5iwuA-1to6A:
0.0		 5iwuA-1to6A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 THR A  66
GLU A 114
PHE A 254
ALA A 253
ILE A 127
 None
 1.44A 5iwuA-1to6A:
0.0		 5iwuA-1to6A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		4 / 7 GLY A 146
ALA A 145
GLY A 140
ILE A 247
 None
 0.70A 5kqyB-1to6A:
undetectable		 5kqyB-1to6A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A  23
ALA A 334
VAL A 284
ILE A 315
CYH A 316
 None
 1.34A 5mlmA-1to6A:
2.9		 5mlmA-1to6A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		3 / 3 VAL A 172
TYR A 149
GLN A 150
 None
 0.53A 5qgkA-1to6A:
0.0		 5qgkA-1to6A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		3 / 3 VAL A 172
TYR A 149
GLN A 150
 None
 0.52A 5qgrA-1to6A:
0.0		 5qgrA-1to6A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		3 / 3 VAL A 172
TYR A 149
GLN A 150
 None
 0.54A 5qgtA-1to6A:
0.0		 5qgtA-1to6A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.84A 5t8hA-1to6A:
undetectable		 5t8hA-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 GLY A 244
ALA A 243
ILE A 259
GLY A 250
ILE A 143
 SO4  A 373 (-3.5A)
SO4  A 373 ( 4.2A)
None
None
None
 0.90A 5t8hA-1to6A:
undetectable		 5t8hA-1to6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 SER A  55
THR A  15
ALA A  20
ILE A  23
GLY A 285
 None
 1.02A 5veuB-1to6A:
undetectable		 5veuB-1to6A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 7 GLY A  93
LEU A  94
LEU A 105
GLY A 132
ILE A 224
 None
None
None
SO4  A 373 (-3.2A)
None
 1.34A 5vkqA-1to6A:
undetectable
5vkqB-1to6A:
undetectable		 5vkqA-1to6A:
11.83
5vkqB-1to6A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 7 GLY A  93
LEU A  94
LEU A 212
GLY A 132
ILE A 224
 None
None
None
SO4  A 373 (-3.2A)
None
 1.25A 5vkqA-1to6A:
undetectable
5vkqB-1to6A:
undetectable		 5vkqA-1to6A:
11.83
5vkqB-1to6A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		6 / 12 LEU A 189
GLY A 130
SER A 261
ILE A 263
GLY A  45
GLY A  44
 None
 1.46A 5zhmB-1to6A:
2.0		 5zhmB-1to6A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ILE A 247
TYR A 228
CYH A 197
LEU A 196
GLY A 249
 None
 1.11A 6bp4B-1to6A:
undetectable		 6bp4B-1to6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.93A 6dgxA-1to6A:
undetectable		 6dgxA-1to6A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 1to6 GLYCERATE KINASE
(Neisseria
meningitidis) 		5 / 12 ALA A 190
ASP A 191
GLY A 244
ILE A 247
ILE A 259
 None
None
SO4  A 373 (-3.5A)
None
None
 0.91A 6dh3A-1to6A:
undetectable		 6dh3A-1to6A:
13.74