SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tot'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 1tot CREB-BINDING PROTEIN
(Mus
musculus) 		4 / 6 GLY A  48
ASP A  52
TYR A   7
TRP A  47
 None
 1.20A 1kf6M-1totA:
undetectable
1kf6N-1totA:
0.0		 1kf6M-1totA:
5.02
1kf6N-1totA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1tot CREB-BINDING PROTEIN
(Mus
musculus) 		4 / 8 ASN A  33
LYS A   1
ASN A  10
THR A   8
 None
 1.44A 4d1yA-1totA:
undetectable
4d1yB-1totA:
undetectable		 4d1yA-1totA:
12.56
4d1yB-1totA:
12.56