SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tp6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  55
LEU A  58
ARG A  66
 None
 0.71A 3hcnB-1tp6A:
undetectable		 3hcnB-1tp6A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 7 GLU A  72
GLU A  92
TYR A  90
GLU A  76
 None
 1.32A 4r87I-1tp6A:
undetectable		 4r87I-1tp6A:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 123
PHE A  40
LEU A  55
PHE A  59
 None
 1.10A 5z84P-1tp6A:
undetectable
5z84W-1tp6A:
undetectable		 5z84P-1tp6A:
21.19
5z84W-1tp6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 123
PHE A  40
LEU A  55
PHE A  59
 None
 1.03A 5z86C-1tp6A:
undetectable
5z86J-1tp6A:
undetectable		 5z86C-1tp6A:
21.19
5z86J-1tp6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 123
PHE A  40
LEU A  55
PHE A  59
 None
 1.10A 5z86P-1tp6A:
undetectable
5z86W-1tp6A:
undetectable		 5z86P-1tp6A:
21.19
5z86W-1tp6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 123
PHE A  40
LEU A  55
PHE A  59
 None
 1.08A 5zcoP-1tp6A:
undetectable
5zcoW-1tp6A:
0.0		 5zcoP-1tp6A:
21.19
5zcoW-1tp6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 123
PHE A  40
LEU A  55
PHE A  59
 None
 1.01A 5zcpC-1tp6A:
undetectable
5zcpJ-1tp6A:
0.0		 5zcpC-1tp6A:
21.19
5zcpJ-1tp6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1tp6 HYPOTHETICAL PROTEIN
PA1314
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 123
PHE A  40
LEU A  55
PHE A  59
 None
 1.10A 5zcpP-1tp6A:
undetectable
5zcpW-1tp6A:
0.0		 5zcpP-1tp6A:
21.19
5zcpW-1tp6A:
19.35