SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tpy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D8C_A_SORA4000_0 (MALATE SYNTHASE G)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	3 / 3	GLN A 204 HIS A 144 PRO A 206	None	0.58A	1d8cA-1tpyA: undetectable	1d8cA-1tpyA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J36_A_LPRA801_1 (ANGIOTENSIN CONVERTING ENZYME)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLN A 49 HIS A 167 GLU A 140 LYS A 52 VAL A 134	None CO3 A 902 (-3.9A) CO3 A 902 ( 3.3A) SAH A1900 ( 4.8A) None	1.37A	1j36A-1tpyA: undetectable	1j36A-1tpyA: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J36_B_LPRB802_1 (ANGIOTENSIN CONVERTING ENZYME)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLN A 49 HIS A 167 GLU A 140 LYS A 52 VAL A 134	None CO3 A 902 (-3.9A) CO3 A 902 ( 3.3A) SAH A1900 ( 4.8A) None	1.37A	1j36B-1tpyA: undetectable	1j36B-1tpyA: 17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHQ_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 8	THR A 168 GLY A 137 GLY A 143 PHE A 139 GLY A 203	None CO3 A 902 (-3.1A) None None 16A A1901 ( 3.7A)	1.39A	1jhqA-1tpyA: undetectable	1jhqA-1tpyA: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHV_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 8	THR A 168 GLY A 137 GLY A 143 PHE A 139 GLY A 203	None CO3 A 902 (-3.1A) None None 16A A1901 ( 3.7A)	1.36A	1jhvA-1tpyA: undetectable	1jhvA-1tpyA: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_A_SAMA302_0 (HYPOTHETICAL PROTEIN PH0226)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	TYR A 16 GLY A 74 ILE A 136 HIS A 141 PHE A 142	SAH A1900 ( 4.1A) SAH A1900 (-3.3A) SAH A1900 (-3.6A) 16A A1901 ( 4.2A) SAH A1900 (-4.6A)	1.11A	1ve3A-1tpyA: 17.0	1ve3A-1tpyA: 25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_IMNA2001_1 (SERUM ALBUMIN)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 10	PHE A 150 ALA A 154 LEU A 158 LEU A 164 LEU A 5	None	1.08A	2bxqA-1tpyA: undetectable	2bxqA-1tpyA: 19.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2FK8_A_SAMA302_0 (METHOXY MYCOLIC ACID SYNTHASE 4)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	12 / 12	THR A 32 TYR A 33 ILE A 71 GLY A 72 GLY A 74 LEU A 95 GLY A 122 TRP A 123 GLU A 124 ILE A 136 ALA A 138 HIS A 141	SAH A1900 (-4.1A) 16A A1901 ( 3.5A) None SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-4.3A) SAH A1900 (-3.1A) SAH A1900 (-4.5A) SAH A1900 (-3.1A) SAH A1900 (-3.6A) SAH A1900 (-3.1A) 16A A1901 ( 4.2A)	0.52A	2fk8A-1tpyA: 39.7	2fk8A-1tpyA: 51.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2FK8_A_SAMA302_1 (METHOXY MYCOLIC ACID SYNTHASE 4)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	3 / 3	SER A 34 THR A 94 GLN A 99	SAH A1900 ( 2.7A) SAH A1900 (-4.1A) SAH A1900 (-3.0A)	0.17A	2fk8A-1tpyA: 39.7	2fk8A-1tpyA: 51.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_A_SAMA301_0 (YCGJ)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 THR A 78 GLU A 124 HIS A 141	SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-3.1A) 16A A1901 ( 4.2A)	0.89A	2gluA-1tpyA: 18.2	2gluA-1tpyA: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 ALA A 138 HIS A 141 PHE A 142	SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-3.1A) 16A A1901 ( 4.2A) SAH A1900 (-4.6A)	0.72A	2gluB-1tpyA: 18.2	2gluB-1tpyA: 21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PFG_A_SAMA264_0 (N-METHYLTRANSFERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	TYR A 16 GLY A 74 LEU A 95 SER A 96 HIS A 141	SAH A1900 ( 4.1A) SAH A1900 (-3.3A) SAH A1900 (-4.3A) None 16A A1901 ( 4.2A)	0.70A	3pfgA-1tpyA: 14.9	3pfgA-1tpyA: 23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_B_ACTB4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	3 / 3	GLY A 74 GLY A 76 THR A 78	SAH A1900 (-3.3A) None None	0.23A	3si7B-1tpyA: undetectable	3si7B-1tpyA: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW7_A_VPXA2001_1 (PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	TYR A 33 HIS A 15 LEU A 243 LEU A 266 ALA A 250	16A A1901 ( 3.5A) None None None None	1.09A	3vw7A-1tpyA: undetectable	3vw7A-1tpyA: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F84_A_SAMA501_0 (GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERAS E)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 THR A 94 LEU A 95 GLN A 99	SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-4.1A) SAH A1900 (-4.3A) SAH A1900 (-3.0A)	0.47A	4f84A-1tpyA: 25.5	4f84A-1tpyA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	6 / 12	TYR A 16 GLY A 72 GLY A 74 LEU A 95 SER A 96 HIS A 141	SAH A1900 ( 4.1A) SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-4.3A) None 16A A1901 ( 4.2A)	0.80A	4krhA-1tpyA: 27.5	4krhA-1tpyA: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	6 / 12	TYR A 16 GLY A 72 GLY A 74 LEU A 95 SER A 96 HIS A 141	SAH A1900 ( 4.1A) SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-4.3A) None 16A A1901 ( 4.2A)	0.81A	4krhB-1tpyA: 27.6	4krhB-1tpyA: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M51_A_BEZA501_0 (AMIDOHYDROLASE FAMILY PROTEIN)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 6	ILE A 169 ILE A 195 PHE A 273 LEU A 236	CO3 A 902 ( 4.6A) 16A A1901 (-4.3A) None 16A A1901 (-4.8A)	0.98A	4m51A-1tpyA: undetectable	4m51A-1tpyA: 19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 6	THR A 168 GLU A 140 THR A 170 LEU A 166	None CO3 A 902 ( 3.3A) None None	1.13A	4pgfA-1tpyA: 4.4	4pgfA-1tpyA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QDJ_A_SAMA301_0 (MAGNESIUM-PROTOPORPH YRIN O-METHYLTRANSFERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	VAL A 12 GLY A 72 GLY A 74 SER A 96 HIS A 141	SAH A1900 (-4.8A) SAH A1900 (-3.2A) SAH A1900 (-3.3A) None 16A A1901 ( 4.2A)	0.85A	4qdjA-1tpyA: 18.1	4qdjA-1tpyA: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_B_SAMB301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 SER A 96 ILE A 136 ALA A 138	SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-3.6A) SAH A1900 (-3.1A)	0.48A	4qtuB-1tpyA: 17.2	4qtuB-1tpyA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 SER A 96 ILE A 136 ALA A 138	SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-3.6A) SAH A1900 (-3.1A)	0.40A	4qtuD-1tpyA: 17.1	4qtuD-1tpyA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 GLY A 76 LEU A 95 ALA A 138	SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-4.3A) SAH A1900 (-3.1A)	0.93A	4uciA-1tpyA: 6.3	4uciA-1tpyA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 GLY A 76 LEU A 95 ALA A 138	SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-4.3A) SAH A1900 (-3.1A)	0.93A	4uciB-1tpyA: 6.6	4uciB-1tpyA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 GLY A 76 LEU A 95 ALA A 138	SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-4.3A) SAH A1900 (-3.1A)	0.96A	4uckA-1tpyA: 6.6	4uckA-1tpyA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 5	GLU A 140 THR A 170 HIS A 155 LEU A 164	CO3 A 902 ( 3.3A) None None None	1.17A	5axaA-1tpyA: 5.5	5axaA-1tpyA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXA_C_ADNC502_2 (ADENOSYLHOMOCYSTEINA SE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 5	GLU A 140 THR A 170 HIS A 155 LEU A 164	CO3 A 902 ( 3.3A) None None None	1.17A	5axaC-1tpyA: 3.6	5axaC-1tpyA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBS_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 8	LEU A 222 LEU A 166 THR A 170 GLN A 229	None	1.13A	5hbsA-1tpyA: undetectable	5hbsA-1tpyA: 17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JKV_A_ASDA602_1 (AROMATASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	ILE A 71 ILE A 157 ALA A 154 LEU A 57 LEU A 68	None	0.99A	5jkvA-1tpyA: undetectable	5jkvA-1tpyA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	GLY A 72 GLY A 74 THR A 94 GLN A 99 VAL A 134	SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-4.1A) SAH A1900 (-3.0A) None	0.96A	5kocB-1tpyA: 27.7	5kocB-1tpyA: 22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	6 / 12	SER A 34 GLY A 72 GLY A 74 THR A 94 GLN A 99 HIS A 141	SAH A1900 ( 2.7A) SAH A1900 (-3.2A) SAH A1900 (-3.3A) SAH A1900 (-4.1A) SAH A1900 (-3.0A) 16A A1901 ( 4.2A)	0.69A	5kocB-1tpyA: 27.7	5kocB-1tpyA: 22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 12	SER A 34 GLY A 72 GLY A 74 SER A 96 GLN A 99	SAH A1900 ( 2.7A) SAH A1900 (-3.2A) SAH A1900 (-3.3A) None SAH A1900 (-3.0A)	0.77A	5kpcB-1tpyA: 27.9	5kpcB-1tpyA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6D8P_A_ACTA814_0 (UNCHARACTERIZED PROTEIN)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	4 / 5	TYR A 16 GLN A 99 THR A 94 LEU A 95	SAH A1900 ( 4.1A) SAH A1900 (-3.0A) SAH A1900 (-4.1A) SAH A1900 (-4.3A)	1.19A	6d8pA-1tpyA: undetectable	6d8pA-1tpyA: 18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EFN_A_SAMA501_0 (SPORULATION KILLING FACTOR MATURATION PROTEIN SKFB)	1tpy	METHOXY MYCOLIC ACID SYNTHASE 2 (Mycobacterium tuberculosis)	5 / 11	PHE A 142 SER A 135 ALA A 138 THR A 168 THR A 170	SAH A1900 (-4.6A) None SAH A1900 (-3.1A) None None	1.47A	6efnA-1tpyA: undetectable	6efnA-1tpyA: 22.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D8C_A_SORA4000_0","MALATE SYNTHASE G","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",3,"GLN A 204;HIS A 144;PRO A 206","None","0.58A","1d8cA-1tpyA:undetectable","1d8cA-1tpyA:17.78"],["1J36_A_LPRA801_1","ANGIOTENSIN CONVERTING ENZYME","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLN A  49;HIS A 167;GLU A 140;LYS A  52;VAL A 134","None;CO3 A 902 (-3.9A);CO3 A 902 ( 3.3A);SAH A1900 ( 4.8A);None","1.37A","1j36A-1tpyA:undetectable","1j36A-1tpyA:17.67"],["1J36_B_LPRB802_1","ANGIOTENSIN CONVERTING ENZYME","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLN A  49;HIS A 167;GLU A 140;LYS A  52;VAL A 134","None;CO3 A 902 (-3.9A);CO3 A 902 ( 3.3A);SAH A1900 ( 4.8A);None","1.37A","1j36B-1tpyA:undetectable","1j36B-1tpyA:17.67"],["1JHQ_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"THR A 168;GLY A 137;GLY A 143;PHE A 139;GLY A 203","None;CO3 A 902 (-3.1A);None;None;16A A1901 ( 3.7A)","1.39A","1jhqA-1tpyA:undetectable","1jhqA-1tpyA:23.45"],["1JHV_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"THR A 168;GLY A 137;GLY A 143;PHE A 139;GLY A 203","None;CO3 A 902 (-3.1A);None;None;16A A1901 ( 3.7A)","1.36A","1jhvA-1tpyA:undetectable","1jhvA-1tpyA:23.45"],["1VE3_A_SAMA302_0","HYPOTHETICAL PROTEIN PH0226","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"TYR A  16;GLY A  74;ILE A 136;HIS A 141;PHE A 142","SAH A1900 ( 4.1A);SAH A1900 (-3.3A);SAH A1900 (-3.6A);16A A1901 ( 4.2A);SAH A1900 (-4.6A)","1.11A","1ve3A-1tpyA:17.0","1ve3A-1tpyA:25.08"],["2BXQ_A_IMNA2001_1","SERUM ALBUMIN","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"PHE A 150;ALA A 154;LEU A 158;LEU A 164;LEU A   5","None","1.08A","2bxqA-1tpyA:undetectable","2bxqA-1tpyA:19.16"],["2FK8_A_SAMA302_0","METHOXY MYCOLIC ACID SYNTHASE 4","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",12,"THR A  32;TYR A  33;ILE A  71;GLY A  72;GLY A  74;LEU A  95;GLY A 122;TRP A 123;GLU A 124;ILE A 136;ALA A 138;HIS A 141","SAH A1900 (-4.1A);16A A1901 ( 3.5A);None;SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-4.3A);SAH A1900 (-3.1A);SAH A1900 (-4.5A);SAH A1900 (-3.1A);SAH A1900 (-3.6A);SAH A1900 (-3.1A);16A A1901 ( 4.2A)","0.52A","2fk8A-1tpyA:39.7","2fk8A-1tpyA:51.57"],["2FK8_A_SAMA302_1","METHOXY MYCOLIC ACID SYNTHASE 4","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",3,"SER A  34;THR A  94;GLN A  99","SAH A1900 ( 2.7A);SAH A1900 (-4.1A);SAH A1900 (-3.0A)","0.17A","2fk8A-1tpyA:39.7","2fk8A-1tpyA:51.57"],["2GLU_A_SAMA301_0","YCGJ","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;THR A  78;GLU A 124;HIS A 141","SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-3.1A);16A A1901 ( 4.2A)","0.89A","2gluA-1tpyA:18.2","2gluA-1tpyA:21.04"],["2GLU_B_SAMB302_0","YCGJ","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;ALA A 138;HIS A 141;PHE A 142","SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-3.1A);16A A1901 ( 4.2A);SAH A1900 (-4.6A)","0.72A","2gluB-1tpyA:18.2","2gluB-1tpyA:21.04"],["3PFG_A_SAMA264_0","N-METHYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"TYR A  16;GLY A  74;LEU A  95;SER A  96;HIS A 141","SAH A1900 ( 4.1A);SAH A1900 (-3.3A);SAH A1900 (-4.3A);None;16A A1901 ( 4.2A)","0.70A","3pfgA-1tpyA:14.9","3pfgA-1tpyA:23.00"],["3SI7_B_ACTB4_0","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",3,"GLY A  74;GLY A  76;THR A  78","SAH A1900 (-3.3A);None;None","0.23A","3si7B-1tpyA:undetectable","3si7B-1tpyA:22.30"],["3VW7_A_VPXA2001_1","PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"TYR A  33;HIS A  15;LEU A 243;LEU A 266;ALA A 250","16A A1901 ( 3.5A);None;None;None;None","1.09A","3vw7A-1tpyA:undetectable","3vw7A-1tpyA:19.24"],["4F84_A_SAMA501_0","GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;THR A  94;LEU A  95;GLN A  99","SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-4.1A);SAH A1900 (-4.3A);SAH A1900 (-3.0A)","0.47A","4f84A-1tpyA:25.5","4f84A-1tpyA:23.42"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",6,"TYR A  16;GLY A  72;GLY A  74;LEU A  95;SER A  96;HIS A 141","SAH A1900 ( 4.1A);SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-4.3A);None;16A A1901 ( 4.2A)","0.80A","4krhA-1tpyA:27.5","4krhA-1tpyA:20.53"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",6,"TYR A  16;GLY A  72;GLY A  74;LEU A  95;SER A  96;HIS A 141","SAH A1900 ( 4.1A);SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-4.3A);None;16A A1901 ( 4.2A)","0.81A","4krhB-1tpyA:27.6","4krhB-1tpyA:20.53"],["4M51_A_BEZA501_0","AMIDOHYDROLASE FAMILY PROTEIN","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",4,"ILE A 169;ILE A 195;PHE A 273;LEU A 236","CO3 A 902 ( 4.6A);16A A1901 (-4.3A);None;16A A1901 (-4.8A)","0.98A","4m51A-1tpyA:undetectable","4m51A-1tpyA:19.96"],["4PGF_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",4,"THR A 168;GLU A 140;THR A 170;LEU A 166","None;CO3 A 902 ( 3.3A);None;None","1.13A","4pgfA-1tpyA:4.4","4pgfA-1tpyA:19.32"],["4QDJ_A_SAMA301_0","MAGNESIUM-PROTOPORPHYRIN O-METHYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"VAL A  12;GLY A  72;GLY A  74;SER A  96;HIS A 141","SAH A1900 (-4.8A);SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;16A A1901 ( 4.2A)","0.85A","4qdjA-1tpyA:18.1","4qdjA-1tpyA:20.86"],["4QTU_B_SAMB301_0","PUTATIVE METHYLTRANSFERASE BUD23","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;SER A  96;ILE A 136;ALA A 138","SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-3.6A);SAH A1900 (-3.1A)","0.48A","4qtuB-1tpyA:17.2","4qtuB-1tpyA:21.43"],["4QTU_D_SAMD301_0","PUTATIVE METHYLTRANSFERASE BUD23","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;SER A  96;ILE A 136;ALA A 138","SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-3.6A);SAH A1900 (-3.1A)","0.40A","4qtuD-1tpyA:17.1","4qtuD-1tpyA:21.43"],["4UCI_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;GLY A  76;LEU A  95;ALA A 138","SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-4.3A);SAH A1900 (-3.1A)","0.93A","4uciA-1tpyA:6.3","4uciA-1tpyA:22.46"],["4UCI_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;GLY A  76;LEU A  95;ALA A 138","SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-4.3A);SAH A1900 (-3.1A)","0.93A","4uciB-1tpyA:6.6","4uciB-1tpyA:22.46"],["4UCK_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;GLY A  76;LEU A  95;ALA A 138","SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-4.3A);SAH A1900 (-3.1A)","0.96A","4uckA-1tpyA:6.6","4uckA-1tpyA:22.46"],["5AXA_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",4,"GLU A 140;THR A 170;HIS A 155;LEU A 164","CO3 A 902 ( 3.3A);None;None;None","1.17A","5axaA-1tpyA:5.5","5axaA-1tpyA:18.64"],["5AXA_C_ADNC502_2","ADENOSYLHOMOCYSTEINASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",4,"GLU A 140;THR A 170;HIS A 155;LEU A 164","CO3 A 902 ( 3.3A);None;None;None","1.17A","5axaC-1tpyA:3.6","5axaC-1tpyA:18.64"],["5HBS_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",4,"LEU A 222;LEU A 166;THR A 170;GLN A 229","None","1.13A","5hbsA-1tpyA:undetectable","5hbsA-1tpyA:17.12"],["5JKV_A_ASDA602_1","AROMATASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"ILE A  71;ILE A 157;ALA A 154;LEU A  57;LEU A  68","None","0.99A","5jkvA-1tpyA:undetectable","5jkvA-1tpyA:21.26"],["5KOC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"GLY A  72;GLY A  74;THR A  94;GLN A  99;VAL A 134","SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-4.1A);SAH A1900 (-3.0A);None","0.96A","5kocB-1tpyA:27.7","5kocB-1tpyA:22.72"],["5KOC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",6,"SER A  34;GLY A  72;GLY A  74;THR A  94;GLN A  99;HIS A 141","SAH A1900 ( 2.7A);SAH A1900 (-3.2A);SAH A1900 (-3.3A);SAH A1900 (-4.1A);SAH A1900 (-3.0A);16A A1901 ( 4.2A)","0.69A","5kocB-1tpyA:27.7","5kocB-1tpyA:22.72"],["5KPC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"SER A  34;GLY A  72;GLY A  74;SER A  96;GLN A  99","SAH A1900 ( 2.7A);SAH A1900 (-3.2A);SAH A1900 (-3.3A);None;SAH A1900 (-3.0A)","0.77A","5kpcB-1tpyA:27.9","5kpcB-1tpyA:22.41"],["6D8P_A_ACTA814_0","UNCHARACTERIZED PROTEIN","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",4,"TYR A  16;GLN A  99;THR A  94;LEU A  95","SAH A1900 ( 4.1A);SAH A1900 (-3.0A);SAH A1900 (-4.1A);SAH A1900 (-4.3A)","1.19A","6d8pA-1tpyA:undetectable","6d8pA-1tpyA:18.93"],["6EFN_A_SAMA501_0","SPORULATION KILLING FACTOR MATURATION PROTEIN SKFB","1tpy","METHOXY MYCOLIC ACID SYNTHASE 2","Mycobacterium tuberculosis",5,"PHE A 142;SER A 135;ALA A 138;THR A 168;THR A 170","SAH A1900 (-4.6A);None;SAH A1900 (-3.1A);None;None","1.47A","6efnA-1tpyA:undetectable","6efnA-1tpyA:22.80"]]