SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		5 / 12 GLU A 219
ILE A 222
PHE A 217
ILE A 171
PHE A 180
 None
 1.14A 1c9hA-1tq4A:
undetectable		 1c9hA-1tq4A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		4 / 6 TYR A 140
GLU A 148
ILE A 153
GLY A  76
 None
 1.08A 1maaB-1tq4A:
undetectable
1maaD-1tq4A:
undetectable		 1maaB-1tq4A:
21.88
1maaD-1tq4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		4 / 7 ALA A 289
PHE A  20
ARG A  45
ASN A  55
 None
 1.28A 1t9wA-1tq4A:
undetectable		 1t9wA-1tq4A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		5 / 12 PHE A 124
VAL A  72
ILE A 248
VAL A 270
LEU A  89
 None
 1.17A 2ft9A-1tq4A:
undetectable		 2ft9A-1tq4A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		3 / 3 ARG A 329
ARG A 332
ILE A  92
 None
 0.89A 4b7qA-1tq4A:
undetectable		 4b7qA-1tq4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		3 / 3 ARG A 329
ARG A 332
ILE A  92
 None
 0.84A 4b7qC-1tq4A:
undetectable		 4b7qC-1tq4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		3 / 3 MET A 144
ASP A 126
PHE A 124
 None
MG  A 501 (-2.8A)
None
 1.01A 4xeyA-1tq4A:
0.0		 4xeyA-1tq4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		3 / 3 MET A 144
ASP A 126
PHE A 124
 None
MG  A 501 (-2.8A)
None
 1.02A 4xeyB-1tq4A:
undetectable		 4xeyB-1tq4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		5 / 12 GLU A 219
ILE A 222
PHE A 217
ILE A 171
PHE A 180
 None
 1.18A 5hkgA-1tq4A:
undetectable		 5hkgA-1tq4A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1tq4 INTERFERON-INDUCIBLE
GTPASE
(Mus
musculus) 		5 / 12 ILE A 165
PHE A 160
LEU A 229
PHE A 240
VAL A 185
 None
 0.95A 5mueA-1tq4A:
undetectable		 5mueA-1tq4A:
21.67