SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1tq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 1tq8 HYPOTHETICAL PROTEIN
RV1636
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 125
ILE A 155
VAL A 112
VAL A 108
 None
 0.83A 3ufnB-1tq8A:
undetectable		 3ufnB-1tq8A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1tq8 HYPOTHETICAL PROTEIN
RV1636
(Mycobacterium
tuberculosis) 		4 / 6 LEU A 123
VAL A 125
LEU A 111
GLU A  99
 None
 0.81A 5tudD-1tq8A:
undetectable		 5tudD-1tq8A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 1tq8 HYPOTHETICAL PROTEIN
RV1636
(Mycobacterium
tuberculosis) 		3 / 3 LEU A  47
VAL A  34
ASP A  35
 None
 0.59A 5x23A-1tq8A:
undetectable		 5x23A-1tq8A:
17.44